Mon May 04 – 10 Stories of The Day!

1 – New NICE Coronavirus Rapid Guidelines

• COVID-19 rapid guideline: antibiotics for pneumonia in adults in hospital – National Institute for Health and Care Excellence
• COVID-19 rapid guideline: gastrointestinal and liver conditions treated with drugs affecting the immune response – National Institute for Health and Care Excellence
• COVID-19 rapid guideline: children and young people who are immunocompromised – National Institute for Health and Care Excellence

See Previous NICE Coronavirus Guidelines: Rapid guidelines and evidence summaries – National Institute for Health and Care Excellence

2 – Restarting planned surgery in the context of the COVID-19 pandemic: A strategy document from the Royal College of Anaesthetists, Association of Anaesthetists, Intensive Care Society and Faculty of Intensive Care Medicine

Related: New Scoring System to Prioritize Medically Necessary Operations (report and commentary)

3 – COVID-19: The CIDRAP Viewpoint Part 1: The Future of the COVID-19 Pandemic: Lessons Learned from Pandemic Influenza – Center for Infectious Disease Research and Policy

News Release: COVID-19: The CIDRAP Viewpoint

Commentary: Three potential futures for Covid-19: recurring small outbreaks, a monster wave, or a persistent crisis – STAT

4 – New Observational Studies Confirm the Safety of Renin–Angiotensin–Aldosterone System Blockers in Patients with Covid-19

Editorial: Inhibitors of the Renin–Angiotensin–Aldosterone System and Covid-19 – New England Journal of Medicine

Study 1: Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19 – New England Journal of Medicine

Study 2: Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19 – New England Journal of Medicine

Study 3: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19 – New England Journal of Medicine

Study 4: Effects Of ARBs And ACEIs On Virus Infection, Inflammatory Status And Clinical Outcomes In COVID-19 Patients With Hypertension: A Single Center Retrospective Study – Hypertension

Commentary: Blood Pressure Drugs Don’t Increase Coronavirus Risk, Studies Find – The New York Times

See also: Observational Study: Renin-Angiotensin System Inhibitors are Not Associated with Severity or Mortality in Hospitalized Patients with Coronavirus Disease (2 other studies on the subject)

5 – Children with Covid-19 in Pediatric Emergency Departments in Italy – New England Journal of Medicine

Related Systematic Review: SARS-CoV-2 Infection in Children and Adolescents (study and commentaries)

6 – Respiratory Pathophysiology of Mechanically Ventilated Patients with COVID-19: A Cohort Study – American Journal of Respiratory and Critical Care Medicine

Commentary: PulmCrit – Is COVID-19 ARDS, pseudoARDS, L, or H? Physiology data from Boston – PulmCrit

7 – Public Health Measures and the Reproduction Number of SARS-CoV-2 – JAMA

Related Editorial: Public Health Interventions for COVID-19: Emerging Evidence and Implications for an Evolving Public Health Crisis – JAMA

8 – COVID-19 – exploring the implications of long-term condition type and extent of multimorbidity on years of life lost: a modelling study – Wellcome Open Research (via @EricTopol see Tweet – Thread)

Commentary: Coronavirus deaths ‘result in more than 10 years of life lost per person’ – Express & Star

9 – Characteristics of ischaemic stroke associated with COVID-19 – Journal of Neurology, Neurosurgery, and Psychiatry

Commentary: Expert reaction to study looking at COVID-19, ischaemic stroke and blood clots – Science media Centre

Related: Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young – New England Journal of Medicine AND Coronavirus’s new mystery: It’s causing strokes in healthy people – Vox AND What’s Behind the Sharp Increase in Large-Vessel Stroke Risk in Young, Healthy COVID-19 Patients? – Neurology Today

10 – Coronavirus Disease (COVID-19) Updates / 04 May 2020 Edition

04 May 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)