Mon, April 1 – 10 Stories of The Day!

1 – 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus – Annals of Rheumatic Diseases (free)

Related Guidelines: Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology – Reumatología Clinica (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus – The Journal of Rheumatology (free PDF)

2 – Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics and the French Society of Anaesthesia and Intensive Care Medicine – Critical Care (free)

Related: Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients – Critical Care (free) AND Extended antibiotic infusions could save lives: Here’s how to do it – PulmCCM (free) AND Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams (link to abstract and commentary)

3 – Efficacy and safety of adjunctive corticosteroids therapy for patients with severe community-acquired pneumonia: A systematic review and meta-analysis – Medicine (free)

Related Meta-analysis: Efficacy and Safety of Adjunctive Corticosteroids Therapy for Severe Community-Acquired Pneumonia in Adults: An Updated Systematic Review and Meta-Analysis – PLOS One (free) AND Adjunctive Systemic Corticosteroids for Hospitalized Community-Acquired Pneumonia: Systematic Review and Meta-Analysis 2015 Update – Scientific Reports (free)

Related Cochrane Review: Is Treatment With Corticosteroids Beneficial for People With Pneumonia? (free)

4 – Prediction of premature all-cause mortality: A prospective general population cohort study comparing machine-learning and standard epidemiological approaches – PLOS One (free)

Commentaries: Artificial intelligence can predict premature death, study finds – University of Nottingham (free) AND Using artificial intelligence to predict mortality – Medical News Today (free)

5 – Report: A Heavy Burden: The Productivity Cost of Illness in Africa – World Health Organization (free)

News Release: Diseases cost the African Region $2.4 trillion a year, says WHO – World Health Organization (free)

6 – Valproate Use In Women and Girls Of Childbearing Years (free PDF)

News Release: Thirteen UK healthcare bodies launch ‘pragmatic’ guidance on valproate use – Royal College of General Practitioners (free)

Commentary: New guidance on valproate use in women – OnMedica (free)

7 – Preventive drugs in the last year of life of older adults with cancer: Is there room for deprescribing? – Cancer (free)

Commentary: Are preventive drugs overused at the end of life in older adults with cancer? – Wiley (free)

8 – Screening for ‘hidden’ pancreatic cancer can put people in jeopardy – STAT (free)

Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free reviews and opinions)

9 – Obesity Hypoventilation Syndrome – European Respiratory Review (free)

Related Review: Obesity hypoventilation syndrome: a current review – Jornal Brasileiro de Pneumologia (free)

10 – Maternal and perinatal mortality and complications associated with caesarean section in low-income and middle-income countries: a systematic review and meta-analysis – The Lancet (free registration required)

Commentaries: Death rates from caesarean section far higher in developing countries, finds major global study – Queen Mary, University of London (free) AND C-section death rates highest in low-income countries – OnMedica (free)