Meta-analysis: Efficacy and safety of tranexamic acid in acute traumatic brain injury

Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials – Intensive Care Medicine

Commentary on Twitter

Tranexamic acid in acute TBI
➡️ 9 RCTs/14,747 pts
➡️ probably NO effect on mortality or disability
➡️ may decrease hematoma expansion on subsequent imaging (likely of minor importance to pts)
➡️ probably NO increased risk of adverse events#FOAMcc @yourICM https://t.co/sqn80NfNv4 pic.twitter.com/dMf8rYowC2

— Intens Care Med (@yourICM) October 21, 2020