M-A | Risk of bias in randomized clinical trials comparing transcatheter and surgical aortic valve replacement

Risk of Bias in Randomized Clinical Trials Comparing Transcatheter and Surgical Aortic Valve Replacement: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Major TAVI Studies Have ‘Methodological Issues,’ INTEGRITTY Group Contends – TCTMD

Commentary on Twitter

Trials comparing TAVI vs SAVR show substantial proportions of deviation from assigned treatment, loss to follow-up, and additional procedures, as well as systematic selective imbalance favoring TAVI that might affect internal validity. https://t.co/n7hwTMEPGu

— JAMA Network Open (@JAMANetworkOpen) January 3, 2023