M-A | Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections.

Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections: a systematic review, GRADE assessment, and network meta-analysis – The Lancet Microbe

Related:

Antiseptic Skin Agents to Prevent Surgical Site Infection After Incisional Surgery: A Randomized, Three-armed Combined Non-inferiority and Superiority Clinical Trial (NEWSkin Prep Study) – Annals of Surgery (link to abstract – $ for full-text)

Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomised controlled trials – The Lancet Infectious Diseases

Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial – The Lancet

Commentary on Twitter

To reduce risk of surgical site infections.
? chlorhexidine in alcohol better than iodine (esp non-clean surgery)
? but only at 2-2.5%. Higher concentration not better!
? olanexidine possible alternative but only 1x RCT@LancetMicrobehttps://t.co/C8FHtEdYlf pic.twitter.com/FXwEOIg4Pf

— Gabriele Pollara (@gpollara) August 22, 2022

Illustrations under a Creative Commons Attribution (CC BY 4.0) license