Intensive glucose control and microvascular outcomes

Effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a meta-analysis of individual participant data from randomised controlled trials – The Lancet Diabetes & Endocrinology (RT @EricTopol see Tweet with interest discussion) (link to abstract – $ required for full-text)

Contradicting the analysis above, a recent report found no significant impact of tight glycemic control on the risk of dialysis / transplantation / renal death, blindness, or neuropathy: Glycemic Control for Patients With Type 2 Diabetes Mellitus: Our Evolving Faith in the Face of Evidence – Circulation (free)

Benefits of intensive glucose control on microvascular outcomes in patients with type 2 diabetes remains controversial.