Fri March 20 – 10 Stories of The Day!

1 – Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists – American Journal of Health-System Pharmacy (free)

2 – Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the Coronavirus Disease 2019 (COVID-19) Pandemic – Journal of the American College of Cardiology (free)

Commentary: CVD in the Setting of COVID-19: Considerations to Prepare Patients, Providers, Health Systems – American College of Cardiology (free)

3 – Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention (free)

4 – COVID-19 Prioritization of Diagnostic Testing – Infectious Diseases Society of America (free PDF)

Summary: IDSA Statement On COVID-19 Testing Recommendations – Infectious Diseases Society of America (free)

5 – New Preliminary Studies with Hydroxychloroquine:

New Clinical Trial: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial – International Journal of Antimicrobial Agents (free PDF)

This was an open-label study with only 42 patients without patient-relevant endpoints. The 6 patients that received Hydroxychloroquine + Azithromycin achieved more efficient virus elimination than control patients.

New in Vitro Study: Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro – Cell Discovery (free)

Related Articles: In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) – Clinical Infectious Diseases (free PDF) AND New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? – International Journal of Antimicrobial Agents (free) AND A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 – Journal of Critical Care (free) AND Of chloroquine and COVID-19 – Antiviral Research (free)

6 – Management of Kidney Stones in 2020 – JAMA (free for a limited period)

Related Guidelines: Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence (free) AND Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians (free) AND Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement – Journal of Nephrology (free) AND Medical Management of Kidney Stones: AUA Guideline (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART II (free) AND The Urological Association of Asia clinical guideline for urinary stone disease – International Journal of Urology (free)

7 – FDA Approves Label Changes to SGLT2 Inhibitors Regarding Temporary Discontinuation of Medication Before Scheduled Surgery – U.S. Food & Drug Administration (free)

Commentary: FDA advises stopping SGLT2 inhibitor treatment prior to surgery – The Hospitalist (free)

“- Canagliflozin, dapagliflozin, and empagliflozin should each be discontinued at least three days before scheduled surgery.

– Ertugliflozin should be discontinued at least four days before scheduled surgery.

– Blood glucose levels should be carefully monitored after discontinuation of the SGLT2 inhibitor and appropriately managed before surgery.”

8 – Association between suicide reporting in the media and suicide: systematic review and meta-analysis – The BMJ (free)

Editorial: Suicide and the media: reporting could cost lives (free)

Commentaries: Responsible communication on suicide in the media is essential if we want to be serious about tackling the stigma surrounding suicide – The BMJ Opinion (free) AND Suicide and the media: reporting could cost lives – University of Bristol (free) AND Media reports of celebrity suicide linked to increased suicide rates – BMJ (free)

9 – Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants – The BMJ (free)

10 – Coronavirus Disease (COVID-19) Updates / 20 March 2020 Edition

20 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)