Fri April 17 – 10 Stories of The Day!

1 – Hydroxychloroquine fails first meaningful RCT – PulmCrit

Original Study: Hydroxychloroquine for Covid-19: No Benefit in New Open-label, Randomized Trial

Related Commentary: Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base – The Lancet Respiratory Medicine

2 – Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 – Journal of Thrombosis and Haemostasis

We congratulate the authors for this significant contribution to the understanding of this disease. 

3 – Coronavirus: Nine in 10 dying have existing illness – BBC

Original Report: Deaths involving COVID-19, England and Wales: deaths occurring in March 2020 – Office for National Statistics

4 – Key Strategies to Prepare for COVID-19 in Long-term Care Facilities (LTCFs) – Centers for Disease Control and Prevention

5 – Estimating the Maximum Capacity of COVID-19 Cases Manageable per Day Given a Health Care System’s Constrained Resources – Annals of Internal Medicine

Editorial: Pandemic Surge Models in the Time of Severe Acute Respiratory Syndrome Coronavirus-2: Wrong or Useful? – Annals of Internal Medicine

6 – Predictive Mathematical Models of the COVID-19 Pandemic: Underlying Principles and Value of Projections – JAMA

Related: The Mathematics of Predicting the Course of the Coronavirus – Wired AND Mathematics of life and death: How disease models shape national shutdowns and other pandemic policies – Science AND How to model a pandemic – The Conversation AND Coronavirus exposes the problems and pitfalls of modelling – The Guardian AND Systematic review and critical appraisal of prediction models for diagnosis and prognosis of COVID-19 infection – medRxiv AND Modelling the models – CEBM University of Oxford

7 – These European Countries Are Slowly Lifting Coronavirus Lockdowns. Here’s What That Looks Like – TIME

Related: When to re-open the economy – Medium AND Strategic preparedness and response plan for the new coronavirus – World Health Organization AND Study: Some Social Distance May Need to Continue Until 2022 AND Ending coronavirus lockdowns will be a dangerous process of trial and error – Science AND ‘Suppress and lift’: Hong Kong and Singapore say they have a coronavirus strategy that works – Science AND Opinions on Lifting Coronavirus Pandemic Lockdowns (opinions and report) AND Scott Gottlieb on how, and when, to end social distancing – Vox AND No country has beaten the coronavirus yet – Vox

8 – Innovation and Transformation in the Response to Covid-19: Seven Areas Where Clinicians Need to Lead – NEJM Catalyst

9 – Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date – American Journal of Roentgenology

Commentary: AJR review of COVID-19 studies cautions against chest CT for coronavirus diagnosis – American Roentgen Ray Society

10 – Coronavirus Disease (COVID-19) Updates / 17 April 2020 Edition

17 April 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)