DNA sequencing may identify an increased risk of relapse in adults with AML prior to hematopoietic cell transplantation

DNA Sequencing to Detect Residual Disease in Adults With Acute Myeloid Leukemia Prior to Hematopoietic Cell Transplant – JAMA (free for a limited period)

News Release: Blood test identifies acute myeloid leukemia patients at greater risk for relapse after bone marrow transplant – National Institutes of Health

Commentary: Blood Test May Identify Patients With AML at Greater Risk of Relapse After Bone Marrow Transplant – The ASCO Post

Commentary on Twitter

Among patients w AML in first remission prior to allogeneic hematopoietic cell transplant, the persistence of residual variants in the blood at an allele fraction ≥0.01% was assoc'd w increased relapse & worse survival vs those w/o these variants. https://t.co/KCnaQ1NRXJ

— JAMA (@JAMA_current) March 11, 2023