Decrease in hospitalizations and liver failure after FDA mandate limiting paracetamol dosage in prescription opioid combinations.

Association of FDA Mandate Limiting Acetaminophen (Paracetamol) in Prescription Combination Opioid Products and Subsequent Hospitalizations and Acute Liver Failure – JAMA (free for a limited period)

Editorial: Moving the Needle to Reduce Acetaminophen (Paracetamol) Hepatotoxicity – JAMA (free for a limited period)

Author Interview: Limiting Acetaminophen in Prescription Combination Opioid Products – JAMA

Video Summary: Acetaminophen (Paracetamol) and Acute Liver Failure – JAMA

News Release: FDA mandate to limit acetaminophen in acetaminophen-opioid medications is associated with reduced serious liver injury – University of Alabama at Birmingham

Commentary on Twitter

The @US_FDA mandate to limit acetaminophen to 325 mg/tablet in prescription combination acetaminophen and opioid medications was associated with a decline in hospitalizations involving acetaminophen and opioid toxicity. https://t.co/6tdqFAI4hG

— JAMA (@JAMA_current) March 7, 2023