Complications of Proton Pump Inhibitor Therapy
30 Jun, 2017 | 15:20h | UTCComplications of Proton Pump Inhibitor Therapy – Gastroenterology (free)
Commentary: Complications of Proton Pump Inhibitor Therapy – PracticeUpdate (free registration required)
Related: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD – Journal of the American Society of Nephrology (link to abstract – registration required for full text) AND Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis – Jama Neurology (link to abstract – subscription required for full text)
The authors of this review argue that the observational studies that brought up the safety issues associated with PPIs (above studies, for example) are insufficient to establish causation and suggest a more balanced approach to PPI prescribing.