Cohort Study | Effect of prosthesis-patient mismatch on long-term clinical outcomes after bioprosthetic aortic valve replacement
10 Mar, 2023 | 14:32h | UTCSummary: The study examined the impact of prosthesis-patient mismatch (PPM) on long-term clinical outcomes following bioprosthetic surgical aortic valve replacement (SAVR). The observational cohort study analyzed data from 16,423 patients who underwent bioprosthetic SAVR in Sweden from 2003 to 2018.
Results showed that increasing grades of PPM were associated with higher long-term mortality and heart failure hospitalization. Severe PPM was linked to an increased risk of heart failure, but moderate PPM did not have significant clinical significance. The study also found that PPM was not associated with aortic valve reintervention. The incidence of moderate and severe PPM has decreased in Sweden since 2013 but remained common.