Clinical trial registration patterns and changes in primary outcomes of randomized clinical trials from 2002 to 2017.

Clinical Trial Registration Patterns and Changes in Primary Outcomes of Randomized Clinical Trials From 2002 to 2017 – JAMA Internal Medicine (free for a limited period)

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This study of 146,462 full-text RCTs found that up to 32% of published trials reported a registry number, and almost 15% of these made substantial changes in primary outcome registration within study duration. Practices have improved over the years. https://t.co/JnXrEpp00J

— JAMA Internal Medicine (@JAMAInternalMed) May 17, 2022