#AHA21 – RCT: In asymptomatic patients with severe aortic stenosis, early surgery improved outcomes compared to conservative treatment.

Aortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis: The AVATAR Trial – Circulation (free for a limited period)

News release: Surgery to replace heart valve beneficial even with no symptoms of severe aortic stenosis – American Heart Association

Commentaries:

AVATAR Supports Early SAVR in Asymptomatic Severe AS Patients – TCTMD

Aortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis – AVATAR – American College of Cardiology

Related study: #AHA19 – Randomized Trial: Early Surgery Improves Outcomes in Asymptomatic Patients with Very Severe Aortic Stenosis

Commentary on Twitter

#OriginalResearch SimPub#AHA21: The #AVATAR RCT of 157 patients with asymptomatic severe #AS and normal LVEF found that early #SAVR associated w/reduced composite outcome of death, MI, stroke or HF hospitalization compared to mgmt. https://t.co/SdMiWHOPnp #AHAJournals pic.twitter.com/jCcWVZfzse

— Circulation (@CircAHA) November 13, 2021