Daily Archives: August 4, 2023 | LinksMedicus Free Medical News & Perspectives

USPSTF | Reaffirming the importance of folic acid to all women planning to or who could become pregnant to prevent neural tube defects

4 Aug, 2023 | 12:15h | UTC

Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement – JAMA

Evidence Report: Folic Acid Supplementation to Prevent Neural Tube Defects: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Patient Page: Folic Acid to Prevent Neural Tube Defects – JAMA

Commentary on Twitter

2023 Recommendation Statement from the USPSTF: all persons planning to or who could become pregnant should take a daily supplement containing 0.4 to 0.8 mg (400 to 800 μg) of folic acid (A recommendation). https://t.co/gdavbWyZZ7 pic.twitter.com/2PAjb0OCBO

— JAMA (@JAMA_current) August 1, 2023

RCT | Mammography screening with AI reduces workload by 44.3% without loss in detection efficacy

4 Aug, 2023 | 12:13h | UTC

Artificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study – The Lancet Oncology (link to abstract – $ for full-text)

News Release: First randomized trial finds AI-supported mammography screening is safe and almost halves radiologist workload – Lancet

Commentaries:

Large Mammography Study Shows Significant Benefits with AI-Aided Screening – Diagnostic Imaging

Expert reaction to interim safety analysis of randomised trial on AI-supported mammography screening – Science Media Centre

RCT | 52-week antidepressant adjunctive therapy did not lead to a statistically significant benefit over 8-week therapy in bipolar I depression

4 Aug, 2023 | 12:11h | UTC

Duration of Adjunctive Antidepressant Maintenance in Bipolar I Depression – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Modern antidepressants may reduce risk of relapse for patients with bipolar depression – University of British Columbia

Commentary on Twitter

Among patients with bipolar I disorder who had remission of depression, there was no significant difference in the incidence of relapse of any mood episode between 8 weeks and 52 weeks of antidepressant treatment. Full results of the BEAM-BD trial: https://t.co/rCkCqIfMb6

— NEJM (@NEJM) August 2, 2023

Study | Removal of thymus in adults linked to increased death, cancer incidence

4 Aug, 2023 | 12:09h | UTC

Health Consequences of Thymus Removal in Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Doctors have long considered the thymus expendable. But could removing it be fatal? – Science

The thymus withers away after puberty. But it may be important for adults – Science News

Thymus gland critical for adult health, study finds – News Medical

Commentary on Twitter

In a study by Kooshesh et al., mortality, the risk of cancer, and levels of proinflammatory cytokines were higher among adults whose thymus had been removed than among control patients. Read the full study results: https://t.co/poaAiELsKG

— NEJM (@NEJM) August 2, 2023

Review | ‘Pragmatic’ trials changing research: Balancing traditional controls with real-world care needs

4 Aug, 2023 | 12:08h | UTC

Clinical Trials Overview: From Explanatory to Pragmatic Clinical Trials – Mayo Clinic Proceedings

Editorial: Introduction to Thematic Reviews on Forward Thinking on Clinical Trials in Clinical Practice – Mayo Clinic Proceedings

Review | Primary aldosteronism: a pragmatic approach to diagnosis and management

4 Aug, 2023 | 12:06h | UTC

Primary Aldosteronism: A Pragmatic Approach to Diagnosis and Management – Mayo Clinic Proceedings

NICE Updated Guideline | Diagnosis and management of lung cancer

4 Aug, 2023 | 12:05h | UTC

Lung cancer: diagnosis and management – National Institute for Health and Care Excellence

ASCO Guideline Update | Management of Stage III Non–Small-Cell Lung Cancer

4 Aug, 2023 | 12:03h | UTC

Management of Stage III Non–Small-Cell Lung Cancer: ASCO Guideline Rapid Recommendation Update – Journal of Clinical Oncology

Commentary: Rapid Guideline Update Offers Key Evidence-Based Recommendations for Stage III NSCLC Management – ASCO Daily News

KDIGO Conference | Managing the symptom burden associated with maintenance dialysis

4 Aug, 2023 | 12:02h | UTC

Managing the symptom burden associated with maintenance dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International

News Release: KDIGO Announces Publication of “Managing the Symptom Burden Associated with Maintenance Dialysis”

Commentary on Twitter

KDIGO is pleased to announce the publication of “Managing the Symptom Burden Associated with Maintenance Dialysis” in @Kidney_Int. The Conference Report is based on the KDIGO Symptom-Based Complications in Dialysis Controversies Conference in May 2022.

Read the News Release:… pic.twitter.com/AZKW9TPgxj

— KDIGO (@goKDIGO) August 1, 2023

M-A | Antenatal corticosteroid exposure linked to negative outcomes in term-born infants

4 Aug, 2023 | 11:59h | UTC

The proportions of term or late preterm births after exposure to early antenatal corticosteroids, and outcomes: systematic review and meta-analysis of 1.6 million infants – The BMJ

Editorial: Antenatal corticosteroids and longer term outcomes – The BMJ

News Releases:

New studies shed more light on potential risks of antenatal steroids – BMJ Newsroom

Researchers find drugs that reduce infant death may lead to long-term health issues – McMaster University

Cohort Study | Antenatal corticosteroid exposure associated with increased incidence of pediatric serious infection

4 Aug, 2023 | 11:57h | UTC

Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study – The BMJ

Editorial: Antenatal corticosteroids and longer term outcomes – The BMJ

M-A | Exploring perinatal interventions and their impact on severe intraventricular hemorrhage in preterm neonates

4 Aug, 2023 | 11:56h | UTC

Interventions to Reduce Severe Brain Injury Risk in Preterm Neonates: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary on Twitter

A meta-analysis by @DrAbdulRazak_MD & colleagues on perinatal interventions are associated with a reduction or increase of IVH and PVL #EBNEOalerts #neoEBM #neotwitter https://t.co/SPzNHwy3HD pic.twitter.com/KDQBSYZjdq

— Evidence-Based Neo (@EBNEO) April 26, 2023

Perspective | Cardiac device infection: removing barriers to timely and adequate treatment

4 Aug, 2023 | 11:54h | UTC

Cardiac device infection: removing barriers to timely and adequate treatment – European Heart Journal

Brief Review | How do I diagnose and treat my patient’s amiodarone-induced thyrotoxicosis?

4 Aug, 2023 | 11:52h | UTC

How do I diagnose and treat my patient’s amiodarone-induced thyrotoxicosis? – Cleveland Clinic Journal of Medicine

Review | Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome

4 Aug, 2023 | 11:50h | UTC

Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome – Cleveland Clinic Journal of Medicine

Review | Autoimmunity and postural orthostatic tachycardia syndrome: Implications in diagnosis and management

4 Aug, 2023 | 11:49h | UTC

Autoimmunity and postural orthostatic tachycardia syndrome: Implications in diagnosis and management – Cleveland Clinic Journal of Medicine

RCT – 2ry analysis | Use of NIPPV, NHFOV post-extubation outperforms NCPAP in neonates with severe respiratory failure or extremely preterm

4 Aug, 2023 | 11:48h | UTC

Effectiveness of Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation vs Noninvasive High-Frequency Oscillatory Ventilation as Support After Extubation of Neonates Born Extremely Preterm or With More Severe Respiratory Failure: A Secondary Analysis of a Randomized Clinical Trial – JAMA Network Open

Original Study: Noninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics

Commentary on Twitter

2nd analysis of NASONE trial in @JAMANetworkOpen examines whether NHFOV is superior in reducing the duration of IMV in comparison to NIPPV and NCPAP in infants born < 28 weeks https://t.co/oWqvO4E5QF

2022 NASONE study: https://t.co/1rfZpaIseN #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/w3Au8s62K7

— Evidence-Based Neo (@EBNEO) July 5, 2023