Daily Archives: July 18, 2023
IARC, WHO agency, identifies aspartame as potentially carcinogenic but probably safe within established acceptable daily intake
18 Jul, 2023 | 13:58h | UTCNews Release: Aspartame hazard and risk assessment results released – World Health Organization
Commentaries:
Expert reaction to IARC and JEFCA summary on aspartame – Science Media Centre
Aspartame Hazard and Risk Assessment Results Released by IARC and JECFA – The ASCO Post
AHA Scientific Statement | Cardiopulmonary impact of electronic cigarettes and vaping products
18 Jul, 2023 | 13:56h | UTCNews Releases:
Top Things to Know: Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products – American Heart Association
Commentary: Vaping’s Risks to CV Health Not Yet Fully Known: AHA – CIDRAP
RCT | Direct oral challenge noninferior to skin testing followed by direct oral challenge in low-risk penicillin allergy patients
18 Jul, 2023 | 13:54h | UTCEfficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
See also: Visual Abstract
News Release: World-first clinical trial to help millions with penicillin allergies – Vanderbilt University Medical Center
Commentary: Trial supports use of direct oral challenge for penicillin allergy – CIDRAP
RCT | Donanemab slows early symptomatic Alzheimer’s progression, but raises serious safety concerns
18 Jul, 2023 | 13:51h | UTCDonanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial – JAMA (free for a limited period)
Editorials:
Donanemab for Alzheimer Disease—Who Benefits and Who Is Harmed? – JAMA (free for a limited period)
Amyloid-Targeting Monoclonal Antibodies for Alzheimer Disease – JAMA (free for a limited period)
Ushering in a New Era of Alzheimer Disease Therapy – JAMA (free for a limited period)
See also: Visual Abstract
Commentary: Expert reaction to results from Eli Lilly on its anti-amyloid drug donanemab – Science Media Centre
Related: RCT | Lecanemab slows cognitive decline in early Alzheimer’s disease but raises safety concerns.
Nationwide Cohort Study | Adolescent hypertension linked with increased stroke risk in young adulthood
18 Jul, 2023 | 13:49h | UTCCommentary: The Relationship Between Adolescent Hypertension and Stroke Risk After Age 40 Years – Neurology Advisor
RCT | Midodrine show promise as an alternative to albumin for the prevention of circulatory disturbance in paracentesis between 3 and 5 L
18 Jul, 2023 | 13:47h | UTC
M-A | Adverse effects of antipsychotics on sleep in patients with schizophrenia
18 Jul, 2023 | 13:45h | UTC
Cohort study | High-risk patent foramen ovale associated with increased decompression illness in scuba divers
18 Jul, 2023 | 13:43h | UTCDecompression Illness in Divers With or Without Patent Foramen Ovale: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: SCUBA divers with PFO at higher risk for decompression illness than previously thought – American College of Physicians
Commentary on Twitter
A study of #ScubaDivers found presence of high-risk PFO was associated with increased risk of decompression illness. Authors recommend divers with PFO should consider not diving or adhering to more conservative protocol: https://t.co/5Glt9B8Xup pic.twitter.com/AYbrDxiL0p
— Annals of Int Med (@AnnalsofIM) July 11, 2023
Cohort study | Poor sensitivity of procalcitonin-on-admission for ruling out bloodstream infections in patients with suspected sepsis
18 Jul, 2023 | 13:39h | UTCReliability of Admission Procalcitonin Testing for Capturing Bacteremia Across the Sepsis Spectrum: Real-World Utilization and Performance Characteristics, 65 U.S. Hospitals, 2008–2017 – Critical Care Medicine (link to abstract – $ for full-text)
RCT | Placebo equally effective as cognitive-behavioral therapy and aripiprazole in preventing psychosis transition
18 Jul, 2023 | 13:37h | UTCPrevention of First-Episode Psychosis in People at Clinical High Risk: A Randomized Controlled, Multicentre Trial Comparing Cognitive-Behavioral Therapy and Clinical Management Plus Low-Dose Aripiprazole or Placebo (PREVENT) – Schizophrenia Bulletin (link to abstract – $ for full-text)
Guideline | Prevention and management of childhood progressive myopia
18 Jul, 2023 | 13:35h | UTC
RCT | Prostatic artery embolization improves symptoms more than combined medical therapy in BPH patients
18 Jul, 2023 | 13:34h | UTC
Cohort Study | Applying machine learning to ECG may improve identification of occlusion MI in individuals with chest pain
18 Jul, 2023 | 13:32h | UTCNews Release: New AI tool beats standard approaches for detecting heart attacks – University of Pittsburgh
Review | Infection prevention and control in the medical imaging environment
18 Jul, 2023 | 13:31h | UTC
Review | CT and chest radiography in evaluation of mechanical circulatory support devices for acute heart failure
18 Jul, 2023 | 13:28h | UTC