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Daily Archives: July 17, 2023

Guideline | Antibiotic therapy in patients with suspected antibiotic allergy

17 Jul, 2023 | 13:59h | UTC

The Dutch Working Party on Antibiotic Policy (SWAB) guideline for the approach to suspected antibiotic allergy – Clinical Microbiology and Infection

 


RCT | No definitive benefit of enoxaparin over placebo in preventing VTE in hospitalized older adults

17 Jul, 2023 | 13:57h | UTC

Enoxaparin versus Placebo to Prevent Symptomatic Venous Thromboembolism in Hospitalized Older Adult Medical Patients – NEJM Evidence

 


What are effective strategies to reduce low-value care? An analysis of 121 randomized deimplementation studies

17 Jul, 2023 | 13:55h | UTC

What are Effective Strategies to Reduce Low-Value Care? An Analysis of 121 Randomized Deimplementation Studies – Journal of Healthcare Quality

 


Retrospective Analysis | Inconsistencies in pediatric drug dosing found in over half of prehospital emergency drug administrations

17 Jul, 2023 | 13:50h | UTC

Deviation From National Dosing Recommendations for Children Having Out-of-hospital Emergencies – Pediatrics

Commentaries:

Children and Drug Dosing Variations When in Transit to the Hospital – AAP Journals Blog

Variation Seen in Dosing of Meds at Prehospital Pediatric Encounters – HealthDay

 


M-A | One-year usage of elastic compression stockings comparable to two for post-thrombotic syndrome prevention

17 Jul, 2023 | 13:49h | UTC

Is it necessary to wear compression stockings and how long should they be worn for preventing post thrombotic syndrome? A meta-analysis of randomized controlled trials – Thrombosis Research

Commentary: Are Compression Stockings Beneficial for Preventing Post-Thrombotic Syndrome After Deep Venous Thrombosis? – NEJM Journal Watch

 


Systematic Review | Prevalence and risk factors of cardiovascular diseases in young adults across 204 countries, 1990-2019

17 Jul, 2023 | 13:47h | UTC

Global, regional, and national burden of cardiovascular diseases in youths and young adults aged 15–39 years in 204 countries/territories, 1990–2019: a systematic analysis of Global Burden of Disease Study 2019 – BMC Medicine

 


Guidelines and recommendations for performance of the fetal echocardiogram

17 Jul, 2023 | 13:45h | UTC

Guidelines and Recommendations for Performance of the Fetal Echocardiogram: An Update from the American Society of Echocardiography

 


Comparative Study | Genomic sequencing yields higher diagnostic results than targeted neonatal gene test in suspected genetic disorders

17 Jul, 2023 | 13:36h | UTC

Rapid Whole-Genomic Sequencing and a Targeted Neonatal Gene Panel in Infants With a Suspected Genetic Disorder – JAMA (link to abstract – $ for full-text)

Author Interview: Genomic Sequencing for Ill Newborns – JAMA

News Release: Genome sequencing highly effective at diagnosing genetic disorders in newborns and infants – Tufts University

 

Commentary on Twitter (thread – click for more)

 


Systematic Review | Criteria to achieve safe antimicrobial intravenous-to-oral switch in hospitalized adult populations

17 Jul, 2023 | 13:34h | UTC

Criteria to achieve safe antimicrobial intravenous-to-oral switch in hospitalised adult populations: a systematic rapid review – BMJ Open

 


Single-arm study | Pembrolizumab plus Lenvatinib shows potential as first-line treatment for advanced non-clear-cell renal cell carcinoma

17 Jul, 2023 | 13:33h | UTC

Pembrolizumab plus lenvatinib as first-line therapy for advanced non-clear-cell renal cell carcinoma (KEYNOTE-B61): a single-arm, multicentre, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)

 


Meta-Analysis | Nearly 6% of first-episode psychosis patients exhibit clinically relevant MRI abnormalities

17 Jul, 2023 | 13:32h | UTC

Prevalence of Neuroradiological Abnormalities in First-Episode Psychosis: A Systematic Review and Meta-analysis – JAMA Psychiatry

News Release: Routine brain scanning may improve clinical care for people with psychosis – University of Oxford

 


Case Series | Cutibacterium acnes endocarditis often misdiagnosed due to absence of typical symptoms and delayed culture results

17 Jul, 2023 | 13:31h | UTC

Clinical Characteristics and Outcomes of Patients With Cutibacterium acnes Endocarditis – JAMA Network Open

 


Review | A health systems approach to critical care delivery in low-resource settings

17 Jul, 2023 | 13:29h | UTC

A health systems approach to critical care delivery in low-resource settings: a narrative review – Intensive Care Medicine

 

Commentary on Twitter (thread – click for more)

 


Cohort Study | Intermittent hypoxemia is associated with unfavorable respiratory outcomes in extremely preterm infants

17 Jul, 2023 | 13:28h | UTC

Cardiorespiratory Monitoring Data to Predict Respiratory Outcomes in Extremely Preterm Infants – American Journal of Respiratory and Critical Care Medicine

 


Cohort Study | Long-acting antiretroviral therapy may achieve virologic suppression in HIV patients with adherence challenges

17 Jul, 2023 | 13:26h | UTC

Demonstration Project of Long-Acting Antiretroviral Therapy in a Diverse Population of People With HIV – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Long-Acting ART Achieves Virologic Suppression for People With HIV – HealthDay

 


TTMV-HPV DNA testing | Promising diagnostic and surveillance tool for HPV-linked oropharyngeal cancer

17 Jul, 2023 | 13:25h | UTC

Performance of Liquid Biopsy for Diagnosis and Surveillance of Human Papillomavirus–Associated Oropharyngeal Cancer – JAMA Otolaryngology–Head & Neck Surgery (free for a limited period)

Invited Commentary: Circulating Human Papillomavirus Tumor DNA—Ready for Prime Time? –  – JAMA Otolaryngology–Head & Neck Surgery (free for a limited period)

 


Review | Guiding the use of invasive cardiac interventions in patients with advanced malignancies

17 Jul, 2023 | 13:23h | UTC

Invasive Cardiac Interventions in Patients With Active, Advanced Solid and Hematologic Malignancies: A Conceptual Framework: JACC: CardioOncology State-of-the-Art Review – JACC: CardioOncology

 


Cohort Study | Mental disorders linked to increased cardiovascular events in young patients

17 Jul, 2023 | 13:20h | UTC

Increased cardiovascular events in young patients with mental disorders: a nationwide cohort study – European Journal of Preventive Cardiology (free for a limited period)

News Release: Under 40s with mental health problems have elevated risks of heart attack and stroke – European Society of Cardiology

 


Brief Review | Neurological diseases in intensive care

17 Jul, 2023 | 13:19h | UTC

Neurological diseases in intensive care – Intensive Care Medicine

 

Commentary on Twitter

 


RCT | 4-week course of subcutaneous ketamine shows efficacy in treatment-resistant depression

17 Jul, 2023 | 13:17h | UTC

Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial – British Journal of Psychiatry

News Release: Ketamine effective for treatment-resistant depression: Clinical trial – University of New South Wales

Related:

RCT | Ketamine non-Inferiority to ECT for nonpsychotic resistant depression

M-A | Electroconvulsive therapy may be superior to ketamine for patients with major depressive episode

RCT | Assessing low-dose ketamine’s antidepressant & antisuicidal effects in patients with treatment-resistant depression

M-A | Efficacy and safety of ketamine vs. electroconvulsive therapy among patients with major depressive episode.

 


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