Daily Archives: June 21, 2023
RCT | LMWH does not increase live birth rates in women with thrombophilia and recurrent miscarriage
21 Jun, 2023 | 13:39h | UTCHeparin for women with recurrent miscarriage and inherited thrombophilia (ALIFE2): an international open-label, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
New study: Many women with recurrent miscarriage are tested for inherited thrombophilia. If confirmed positive, daily subcutaneous low-molecular-weight heparin (LMWH) is given.
This is despite an absence of evidence that such treatment is beneficial ? https://t.co/0IuFhvjlZr
— The Lancet (@TheLancet) June 2, 2023
Acute heart failure: differential diagnosis and treatment
21 Jun, 2023 | 13:37h | UTCAcute heart failure: differential diagnosis and treatment – European Heart Journal Supplements
Qualitative Study | International perspectives on modifications to the surgical safety checklist
21 Jun, 2023 | 13:36h | UTCInternational Perspectives on Modifications to the Surgical Safety Checklist – JAMA Network Open
Invited Commentary: Modifications of the World Health Organization’s Surgical Safety Checklist—Ways Forward to Ensure Sustainable Implementation – JAMA Network Open
Commentary on Twitter
Qualitative study: >10 years after the surgical safety checklist was developed, systems should consider checklist modification to improve safety, teamwork & buy-in. https://t.co/5xisRqzWkf @N8turl3y @MaryEBrindle @ucalgarymed @ariadnelabs
— JAMA Network Open (@JAMANetworkOpen) June 7, 2023
Cohort Study | Dengue patients at high risk of cholecystitis and pancreatitis within 30 days
21 Jun, 2023 | 13:34h | UTC
Brief Review | Selection bias due to conditioning on a collider
21 Jun, 2023 | 13:32h | UTCSelection bias due to conditioning on a collider – The BMJ
Review | Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation
21 Jun, 2023 | 13:31h | UTC
M-A | CRP at 5 mg/L cut-off efficient for tuberculosis screening in HIV outpatients
21 Jun, 2023 | 13:30h | UTC
Commentary on Twitter
ERR: C-reactive protein at a 5 mg cut-off and two newly developed clinical prediction models from this study show clinical utility for TB screening among outpatient PLHIV, while the WHO-recommended four-symptom screen showed suboptimal clinical utility https://t.co/msm13KXR0Y pic.twitter.com/O0wS1Xv4da
— ERS publications (@ERSpublications) June 11, 2023
Review | Deadly drug rashes: early recognition and multidisciplinary care
21 Jun, 2023 | 13:28h | UTC
Review | Serial serum lipase testing after the initial diagnostic workup for inpatients with acute pancreatitis: what is the evidence?
21 Jun, 2023 | 13:27h | UTC
Consensus Statement | Anatomy, imaging, and nomenclature of congenital aortic root malformations
21 Jun, 2023 | 13:25h | UTC
The future of artificial intelligence in intensive care: moving from predictive to actionable AI
21 Jun, 2023 | 13:24h | UTC
Position statement | Gastrointestinal bleeding and endoscopic procedures in patients on antiplatelet and/or anticoagulant therapy
21 Jun, 2023 | 13:22h | UTCPosition statement from the Indian Society of Gastroenterology, Cardiological Society of India, Indian Academy of Neurology and Vascular Society of India on gastrointestinal bleeding and endoscopic procedures in patients on antiplatelet and/or anticoagulant therapy – Indian Journal of Gastroenterology (if the link is paywalled, try this one)
Review | Update in the treatment of the complications of cirrhosis
21 Jun, 2023 | 13:20h | UTCUpdate in the Treatment of the Complications of Cirrhosis – Clinical Gastroenterology and Hepatology
Cohort Study | Stopping immunotherapy in patients that are progression-free at 2 years seems feasible in advanced NSCLC
21 Jun, 2023 | 13:19h | UTCAssociation Between Duration of Immunotherapy and Overall Survival in Advanced Non–Small Cell Lung Cancer – JAMA Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Study of patients with #NSCLC showed no survival difference between 2-yr fixed duration vs indefinite #immunotherapy, suggesting that IO can be d/c at 2 yrs. @PennCancer @flatironhealth @lovasunMD @Ron_cology @CharuAggarwalMD #ASCO23 https://t.co/EWyneghc8a pic.twitter.com/HkyIwwtJiM
— JAMA Oncology (@JAMAOnc) June 4, 2023
Review | Traumatic hemorrhage and chain of survival
21 Jun, 2023 | 13:17h | UTC
RCT | Rituximab and MMF combo improves lung function vs. MMF in interstitial lung disease with NSIP pattern, but may increase infection risk
21 Jun, 2023 | 13:16h | UTCRituximab and mycophenolate mofetil combination in patients with interstitial lung disease (EVER-ILD): a double-blind, randomised, placebo-controlled trial – European Respiratory Journal (link to abstract – $ for full-text)
Commentary on Twitter
ERJ: Rituximab plus MMF is associated with benefits in lung function and progression-free survival compared with MMF plus placebo after 24 weeks of treatment. The safety profile of rituximab plus MMF was similar to that of MMF plus placebo. https://t.co/Mv0IuzLljz pic.twitter.com/1igrt6uDK4
— ERS publications (@ERSpublications) June 11, 2023
Review | Glomerular hematuria and the utility of urine microscopy
21 Jun, 2023 | 13:14h | UTC
Commentary on Twitter
Glomerular Hematuria and the Utility of Urine Microscopy: A Reviewhttps://t.co/SsibhaJqnY (FREE)@MLReynoldsMD @AmyMottl @ANCAUNC @VDereBean pic.twitter.com/kEhmKSL2Ij
— AJKD (@AJKDonline) June 11, 2023
Review | Ultrasonographic assessment of diaphragmatic function in the management of patients with acute respiratory failure
21 Jun, 2023 | 13:12h | UTC
Review | Pulmonary rehabilitation and physical interventions
21 Jun, 2023 | 13:11h | UTCPulmonary rehabilitation and physical interventions – European Respiratory Review
Commentary on Twitter
ERR: Pulmonary rehabilitation that includes individualised exercise training is effective in patients with stable COPD and those who have suffered an exacerbation. Remaining challenges are to increase uptake and access to and personalisation of programmes. https://t.co/NSoASus6TW pic.twitter.com/JRl7dCOZrm
— ERS publications (@ERSpublications) June 12, 2023
The foot in diabetes – a reminder of an ever-present risk
21 Jun, 2023 | 13:10h | UTCThe foot in diabetes – a reminder of an ever-present risk – Clinical Medicine Journal
Related: Guideline Series | Prevention and management of diabetes-related foot disease