Daily Archives: June 1, 2023

ASH 2023 Guidelines for management of venous thromboembolism | Thrombophilia testing

1 Jun, 2023 | 12:22h | UTC

American Society of Hematology 2023 Guidelines for Management of Venous Thromboembolism: Thrombophilia Testing – Blood Advances

 

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AASLD-IDSA Guideline | Updated 2023 recommendations for the testing, management, and treatment of Hepatitis C virus infection

1 Jun, 2023 | 12:21h | UTC

Hepatitis C Guidance 2023 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection – Clinical Infectious Diseases

 

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RCT | Dupilumab improves lung function and reduces exacerbations in COPD patients with elevated eosinophils

1 Jun, 2023 | 12:20h | UTC

Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Dupilumab Improves Outcomes for COPD, Type 2 Inflammation in Randomized Trial – HCP Live

 

Commentary on Twitter

Presented at #ATS2023: In the BOREAS trial, dupilumab resulted in a lower annualized rate of exacerbations than placebo among patients with COPD and an elevated blood eosinophil count. Full trial results: https://t.co/9IWZr3YqsN

— NEJM (@NEJM) May 21, 2023

 

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SR | Individual‐level interventions for reducing occupational stress in healthcare workers

1 Jun, 2023 | 12:18h | UTC

Individual‐level interventions for reducing occupational stress in healthcare workers – Cochrane Library

News Release: Stress-management interventions may help individual healthcare workers for at least a year – Cochrane Library

 

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Phase 2b RCT | Danuglipron, an oral GLP-1R agonist, reduces body weight and improves glycemic control in type 2 diabetes

1 Jun, 2023 | 12:17h | UTC

Efficacy and Safety of Oral Small Molecule Glucagon-Like Peptide 1 Receptor Agonist Danuglipron for Glycemic Control Among Patients With Type 2 Diabetes: A Randomized Clinical Trial – JAMA Network Open

Commentary: What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes? – News Medical

 

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SR | Systematic review finds 16.4-36.18 severe bleedings, 7.62-8.5 perforations per 10,000 colonoscopies

1 Jun, 2023 | 12:15h | UTC

An Estimate of Severe Harms Due to Screening Colonoscopy: A Systematic Review – The Journal of the American Board of Family Medicine

 

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Expert Consensus | Nephrotoxic potential of 195 medications in the non-intensive care setting

1 Jun, 2023 | 12:14h | UTC

Expert Consensus on the Nephrotoxic Potential of 195 Medications in the Non-intensive Care Setting: A Modified Delphi Method – Drug Safety

 

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Consensus Paper | Organ donation in the surgical ICU

1 Jun, 2023 | 12:12h | UTC

Organ donation in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document – Trauma Surgery & Acute Care Open

 

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M-A | Noninvasive ventilation in patients with acute hypoxemic respiratory failure

1 Jun, 2023 | 12:11h | UTC

Noninvasive ventilation in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis of randomized controlled trials – Scientific Reports

 

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M-A | Maternal alcohol consumption and the risk of miscarriage in the first and second trimesters

1 Jun, 2023 | 12:10h | UTC

Maternal alcohol consumption and the risk of miscarriage in the first and second trimesters: a systematic review and dose–response meta-analysis – Acta Obstetricia et Gynecologica Scandinavica

 

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RCT | JAK inhibitor Upadacitinib shows superiority over placebo for moderate-to-severe Crohn’s disease

1 Jun, 2023 | 12:08h | UTC

Upadacitinib Induction and Maintenance Therapy for Crohn’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)

 

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SR | Biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome

1 Jun, 2023 | 12:06h | UTC

Biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a systematic review – BMC Medicine

 

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Cohort Study | Associations of menstrual cycle regularity and length with cardiovascular diseases

1 Jun, 2023 | 12:07h | UTC

Associations of Menstrual Cycle Regularity and Length With Cardiovascular Diseases: A Prospective Study From UK Biobank – Journal of the American Heart Association

News Release: Long or short menstrual cycles linked to higher risk of CVD including atrial fibrillation – American Heart Association

 

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Review | Deprescribing interventions for gabapentinoids in adults

1 Jun, 2023 | 12:05h | UTC

Deprescribing interventions for gabapentinoids in adults: a scoping review – British Journal of Clinical Pharmacology

 

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Guideline | Onychomycosis

1 Jun, 2023 | 12:01h | UTC

Guideline onychomycosis – Journal of the German Society of Dermatology

 

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RCT | Adapted mindfulness training shows efficacy in reducing elevated office blood pressure

1 Jun, 2023 | 12:03h | UTC

Effect of Adapted Mindfulness Training in Participants With Elevated Office Blood Pressure: The MB‐BP Study: A Randomized Clinical Trial – Journal of the American Heart Association

 

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Cluster RCT | Point-of-care CRP testing cuts antibiotic prescriptions in respiratory illnesses in primary care

1 Jun, 2023 | 11:58h | UTC

Implementation of point-of-care testing of C-reactive protein concentrations to improve antibiotic targeting in respiratory illness in Vietnamese primary care: a pragmatic cluster-randomised controlled trial – The Lancet Infectious Diseases

Commentary: Use of CRP testing reduced antibiotics for respiratory infections, trial finds – CIDRAP

 

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Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials

1 Jun, 2023 | 11:56h | UTC

Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials – BMC Medicine

 

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SR | Prevalence of clinical signs, symptoms and comorbidities at diagnosis of acromegaly

1 Jun, 2023 | 11:52h | UTC

Prevalence of clinical signs, symptoms and comorbidities at diagnosis of acromegaly: a systematic review in accordance with PRISMA guidelines – Pituitary

 

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Study finds potential glaucoma risk in patients using calcium channel blockers

1 Jun, 2023 | 11:51h | UTC

Association of systemic medication use with glaucoma and intraocular pressure: the E3 Consortium – Ophthalmology

Commentary: Calcium Channel Blocker Use Associated with Higher Prevalence of Glaucoma – HCP Live

 

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Cardiac toxicities in multiple myeloma: an updated and a deeper look into the effect of different medications and novel therapies

1 Jun, 2023 | 11:48h | UTC

Cardiac toxicities in multiple myeloma: an updated and a deeper look into the effect of different medications and novel therapies – Blood Cancer Journal

 

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