Daily Archives: February 16, 2023
M-A | Association between antimicrobial stewardship programs and antibiotic use globally
16 Feb, 2023 | 15:21h | UTCCommentaries:
Antimicrobial Stewardship Programs Beneficial for Cutting Antibiotic Use – HealthDay
RCT | Rivaroxaban shows promise compared to Enoxaparin in the acute phase of an acute coronary syndrome
16 Feb, 2023 | 15:20h | UTCInvited Commentary: Rivaroxaban for Patients With Acute Coronary Syndromes—Where Do We Stand? – JAMA Network Open
Commentary on Twitter
The H-REPLACE RCT: short-term rivaroxaban (5mg 2x/day) was noninferior to enoxaparin in safety + efficacy during 6-month follow-up among patients with acute coronary syndrome who missed the primary reperfusion window and before selective revascularization. https://t.co/TIHOwGSWjJ
— JAMA Network Open (@JAMANetworkOpen) February 10, 2023
Guideline | Diagnosis and management of subarachnoid hemorrhage caused by a ruptured aneurysm
16 Feb, 2023 | 15:23h | UTC
RCT | Laser treatment does not improve sexual dysfunction in survivors of breast cancer
16 Feb, 2023 | 15:19h | UTCInvited commentary: Genitourinary Syndrome of Menopause and the False Promise of Vaginal Laser Therapy – JAMA Network Open
Related:
RCT | Laser no better than sham treatment for genitourinary syndrome of menopause
M-A | Carbon dioxide laser vs. vaginal estrogen for genitourinary syndrome of menopause.
Perspective: From vaginal laser treatment to spa breaks – it’s the great menopause gold rush.
Commentary on Twitter
The LIGHT Trial RCT: Vaginal laser therapy does not improve sexual dysfunction/genitourinary syndrome of menopause in breast cancer survivors receiving aromatase inhibitors when added to first line therapy based on moisturizers and vibrator stimulation. https://t.co/jdVDgHe9HC
— JAMA Network Open (@JAMANetworkOpen) February 10, 2023
Regulations on palliative sedation: an international survey across eight European countries
16 Feb, 2023 | 15:17h | UTC
RCT | Adjuvant nivolumab plus ipilimumab not better than placebo for localized renal cell carcinoma after nephrectomy
16 Feb, 2023 | 15:15h | UTCAdjuvant nivolumab plus ipilimumab versus placebo for localised renal cell carcinoma after nephrectomy (CheckMate 914): a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Hidden harms of indoor air pollution — five steps to expose them
16 Feb, 2023 | 15:13h | UTCHidden harms of indoor air pollution — five steps to expose them – Nature
Commentary on Twitter
Dirty outdoor air might grab the headlines, but learning how pollutants inside buildings form, accumulate and affect our health is equally crucial, argue Alastair Lewis, Deborah Jenkins and @CMO_England in a @Nature Comment article. https://t.co/C8MrWEwfE2
— Nature Portfolio (@NaturePortfolio) February 8, 2023
Excess mortality among US physicians during the COVID-19 pandemic
16 Feb, 2023 | 15:14h | UTCExcess Mortality Among US Physicians During the COVID-19 Pandemic – JAMA Internal Medicine
Commentaries:
More than 600 US doctors died than expected early in COVID pandemic – CIDRAP
Hundreds of U.S. Doctors Lost Their Lives During Pandemic – HealthDay
Commentary on Twitter
From March 2020 to December 2021, US physicians experienced over 600 more deaths than expected, but substantially fewer than the US general population. Older physicians who provide direct patient care were at the highest risk. https://t.co/7Un0h7VC8X
— JAMA Internal Medicine (@JAMAInternalMed) February 8, 2023
Rare, overlooked, or underappreciated causes of recurrent abdominal pain: a primer for gastroenterologists
16 Feb, 2023 | 15:12h | UTC
Commentary from the author on Twitter
Our paper in @AGA_CGH looking at Rare, Overlooked, or Underappreciated Causes of Recurrent Abdominal Pain: A Primer for Gastroenterologists
Thanks to @umfoodoc @dbrennerGIMD and my mentor #DrBrandt @MonteGastro for including me in this important work https://t.co/91MKLqvgLy pic.twitter.com/HcHiRehhNI
— Marc Fenster (@Marcfenster1) September 28, 2022
M-A | Blood pressure lowering effects of B-blockers as add-on or combination therapy
16 Feb, 2023 | 15:10h | UTC
RCT | Orlistat and a low-carb diet show promising results for the treatment of Metabolic-Associated Fatty Liver Disease
16 Feb, 2023 | 15:07h | UTCSummary: The study aimed to compare the effects of orlistat or a high-protein/lower-carbohydrate diet with a control diet in Asian patients with obesity and metabolic-associated fatty liver disease (MAFLD) over 24 weeks. The primary endpoint was the relative change in liver fat content (LFC) assessed by MRI-PDFF. A total of 118 patients were randomly assigned to the control group, orlistat group, or experimental diet group. All three groups demonstrated improvement in liver steatosis at week 24, with the orlistat group and the experimental diet group both showing a significant decrease in LFC compared to the control group.*
*Note: This summary was created through the collaboration of a medical editor and ChatGPT.
10-year follow-up on preterm prelabor rupture of membranes: induced labor vs. expectant management childhood outcomes
16 Feb, 2023 | 15:05h | UTCSummary: This study aimed to compare the long-term outcomes of children born after singleton pregnancies complicated by preterm prelabor rupture of membranes and managed by induction of labor vs. expectant management in RCTs undergone between 2007 and 2011. The study assessed the children’s cognition, motor function, and behavior as the primary outcomes. It found that expectant management did not improve long-term outcomes compared to induction of labor for children born after pregnancies with preterm prelabor (between 34 0/7 and 36 6/7 weeks of pregnancy) rupture of membranes. The confidence in the results of this follow-up study is diminished because only 35% of the children who participated in the original trials participated in the follow-up study.
*Note: This summary was created through the collaboration of a medical editor and ChatGPT.
M-A | Worldwide prevalence of antibiotic-associated Stevens-Johnson syndrome and toxic epidermal necrolysis
16 Feb, 2023 | 15:04h | UTCSummary: The article examined the prevalence Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) associated with antibiotics worldwide. The analysis included 38 studies involving 2,917 patients, which showed that 28% of SJS/TEN cases were associated with antibiotics. Among antibiotic-associated SJS/TEN, the sulfonamide class was associated with 32% of cases, followed by penicillins, cephalosporins, fluoroquinolones, and macrolides.
Article: Worldwide Prevalence of Antibiotic-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis – JAMA Dermatology (free for a limited period)
*Note: This summary was created through the collaboration of a medical editor and ChatGPT.
Pediatric edible cannabis exposures and acute toxicity in the US: 2017–2021
16 Feb, 2023 | 15:00h | UTCPediatric Edible Cannabis Exposures and Acute Toxicity: 2017–2021 – Pediatrics
Commentaries:
The Number of American Kids Eating Cannabis Has Surged Dramatically – Science Alert
2017 to 2021 Saw Increase in Pediatric Edible Cannabis Exposure – HealthDay
Reconstructive burnout after mastectomy: implications for patient selection
16 Feb, 2023 | 15:02h | UTCCommentary: One in Four Patients Experience Breast Reconstruction Burnout – HealthDay
Cohort Study | Antibiotics, hormonal therapies, oral contraceptives, and NSAIDS linked to increased risk of inflammatory bowel disease
16 Feb, 2023 | 14:59h | UTCAssociations of Antibiotics, Hormonal Therapies, Oral Contraceptives, and Long-Term NSAIDS With Inflammatory Bowel Disease: Results From the Prospective Urban Rural Epidemiology (PURE) Study – Clinical Gastroenterology and Hepatology (link to abstract – $ for full-text)
Perspective | A short history of saturated fat: the making and unmaking of a scientific consensus
16 Feb, 2023 | 14:57h | UTC
Commentary from the author on Twitter (thread – click for more)
My latest: "A short history of saturated fat: the making and unmaking of a scientific consensus"
Do saturated fats cause heart disease? The science was always weak. Fear of these fats was started by American Heart Assoc. in 1961 based on a flawed study?https://t.co/J3cOlfzTi6— Nina Teicholz (@bigfatsurprise) December 14, 2022
RCT | Intraoperative intravenous infusion of esmketamine in patients undergoing thoracic surgery
16 Feb, 2023 | 14:56h | UTC
M-A | Radiofrequency therapies for trigeminal neuralgia
16 Feb, 2023 | 14:51h | UTC
M-A | Efficacy of endovascular therapy for basilar and vertebral artery occlusion
16 Feb, 2023 | 14:50h | UTCRelated:
M-A | Mechanical thrombectomy in acute basilar artery stroke.
A good use of time? Providing evidence for how effort is invested in primary and secondary outcome data collection in trials
16 Feb, 2023 | 14:48h | UTC
SR | The impact of interventions to prevent neonatal healthcare-associated infections in low- and middle-income countries
16 Feb, 2023 | 14:47h | UTC
SR | The impact of antimicrobial stewardship in children in low- and middle-income countries
16 Feb, 2023 | 14:46h | UTC
Digital health interventions for adult patients with cancer evaluated in randomized controlled trials: scoping review
16 Feb, 2023 | 14:45h | UTC
M-A | Cost-effectiveness of internet interventions compared with treatment as usual for people with mental disorders
16 Feb, 2023 | 14:43h | UTC