Daily Archives: February 6, 2023 | LinksMedicus Free Medical News & Perspectives

Updating international consensus on best practice in care of the dying: a Delphi study

6 Feb, 2023 | 13:41h | UTC

Updating international consensus on best practice in care of the dying: A Delphi study – Palliative Medicine

ACG Guideline | Management of patients with acute lower gastrointestinal bleeding

6 Feb, 2023 | 13:43h | UTC

Management of Patients With Acute Lower Gastrointestinal Bleeding: An Updated ACG Guideline

Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Endoscopy

Randomized Trial: Efficacy and Safety of Early vs. Elective Colonoscopy for Acute Lower Gastrointestinal Bleeding

[Abstract Only] Systematic Review: Early Colonoscopy Does Not Improve Outcomes of Patients with Lower Gastrointestinal Bleeding

Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology – Gut

Update guidelines for women with HIV who are virally suppressed incorporate breastfeeding their infants as a viable option

6 Feb, 2023 | 13:40h | UTC

Update to Clinical Guidelines for Infant Feeding Supports Shared Decision Making: Clarifying Breastfeeding Guidance for People with HIV – HIV.gov

Commentary on Twitter

Updated guidelines now incorporate breastfeeding options for PWH with suppressed VL on ART. https://t.co/JPR1K8zzv6

— Carlos del Rio (@CarlosdelRio7) February 3, 2023

Phase 2 RCT | Baxdrostat for treatment-resistant hypertension

6 Feb, 2023 | 13:38h | UTC

Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: A Study of CIN-107 in Adults With Treatment-Resistant Hypertension – BrigHTN – American College of Cardiology

Commentary on Twitter (thread – click for more)

Aldosterone has long been a pharmacologic target for the treatment of hypertension. However, a new small-molecule drug called baxdrostat inhibits aldosterone synthase in patients with treatment-resistant hypertension. 1/14 pic.twitter.com/F27WE4Wa1d

— NEJM (@NEJM) February 3, 2023

Opinion | Hospital masking should be optional

6 Feb, 2023 | 13:37h | UTC

Hospital masking should be optional – Sensible Medicine

RCT | Personalized accelerated pacing may improve QOL in patients with heart failure with preserved EF

6 Feb, 2023 | 13:35h | UTC

Effect of Personalized Accelerated Pacing on Quality of Life, Physical Activity, and Atrial Fibrillation in Patients With Preclinical and Overt Heart Failure With Preserved Ejection Fraction: The myPACE Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

News Release: Speeding up heart rate helps heart failure patients with stiff hearts – University of Minnesota Medical School

Commentary on Twitter

In study of patients with HFpEF and pacemakers, moderately accelerated pacing (median pacing rate 75bpm) improved health-related QOL, natriuretic peptide levels, activity levels, and Afib compared w/ standard 60 bpm setting. https://t.co/Ow3W3qD6DM @maggieinfeld @markusmeyermd

— JAMA Cardiology (@JAMACardio) February 1, 2023

Case-control study | Estimation of vaccine effectiveness of CoronaVac and BNT162b2 in patients with SARS-CoV-2 Omicron

6 Feb, 2023 | 13:32h | UTC

Estimation of Vaccine Effectiveness of CoronaVac and BNT162b2 Against Severe Outcomes Over Time Among Patients With SARS-CoV-2 Omicron – JAMA Network Open

Commentary on Twitter

The CoronaVac and BNT162b2 (Pfizer) vaccines were effective against severe outcomes due to Omicron (74-77%), but protection among older individuals in Hong Kong was more likely to wane 6 months after the second dose; boosters can bring effectiveness >90%. https://t.co/kqgwryJ1kT

— JAMA Network Open (@JAMANetworkOpen) February 3, 2023

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

6 Feb, 2023 | 13:31h | UTC

ChatGPT and the Future of Medical Writing – Radiology

Editorials:

ChatGPT Is Shaping the Future of Medical Writing but Still Requires Human Judgment – Radiology

ChatGPT and Other Large Language Models Are Double-edged Swords – Radiology

Commentaries:

AI program ChatGPT now has a published article in Radiology—is it any good? – Health Imaging

Peer-Reviewed Journal Publishes Paper Written Almost Entirely by ChatGPT— It required close editing, human co-author said – MedPage Today (free registration required)

ChatGPT: five priorities for research – Nature

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

ChatGPT is fun, but not an author – Science

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Abstracts written by ChatGPT fool scientists

ChatGPT: five priorities for research

6 Feb, 2023 | 13:30h | UTC

ChatGPT: five priorities for research – Nature

ChatGPT and the Future of Medical Writing – Radiology

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

The path forward for ChatGPT in academia – Lumo’s Newsletter

ChatGPT is fun, but not an author – Science

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Abstracts written by ChatGPT fool scientists

RCT | Machine perfusion is superior to therapeutic hypothermia for reducing delayed graft function after kidney transplantation

6 Feb, 2023 | 13:28h | UTC

Hypothermia or Machine Perfusion in Kidney Donors – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Machine Perfusion of Kidneys Protects Against Delayed Graft Function – HealthDay

Commentary with video on Twitter

Hypothermia of brain-dead kidney donors and machine perfusion of the kidney can reduce delayed graft function, but whether hypothermia is as effective as machine perfusion is unclear. New research findings are summarized in a short video. https://t.co/mL0YQZYoK1 pic.twitter.com/ANnJl27mkl

— NEJM (@NEJM) February 4, 2023

Guideline | Urticaria management

6 Feb, 2023 | 13:25h | UTC

Part 1: Classification and diagnosis of urticaria – German-language adaptation of the international S3 Guideline – Journal of the German Dermatological Society

Part 2: Treatment of urticaria – German-language adaptation of the international S3 guideline – Journal of the German Dermatological Society

The ‘Ten Commandments’ of the 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

6 Feb, 2023 | 13:24h | UTC

The ‘Ten Commandments’ of the 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension – European Heart Journal

Original Guideline: #ESCCongress | 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.

Point/Counterpoint | Are obstructive sleep apnea phenotypes clinically useful?

6 Feb, 2023 | 13:21h | UTC

POINT: Are OSA Phenotypes Clinically Useful? Yes – CHEST

COUNTERPOINT: Are OSA Phenotypes Clinically Useful? No – CHEST

Rebuttal From Dr Edwards et al – CHEST

Rebuttal From Dr Tolbert et al – CHEST

Guideline | Diagnosis and management of otitis media with effusion in children

6 Feb, 2023 | 13:23h | UTC

Clinical practice guidelines for the diagnosis and management of otitis media with effusion (OME) in children in Japan – 2022 update – Auris Nasus Larynx

Case-control study | Association of anthracycline with heart failure in patients treated for breast cancer or lymphoma, 1985-2010

6 Feb, 2023 | 13:20h | UTC

Association of Anthracycline With Heart Failure in Patients Treated for Breast Cancer or Lymphoma, 1985-2010 – JAMA Network Open

Invited Commentary: Heart Failure in Patients With Cancer Treated With Anthracyclines—Revisiting the Foundation of Cardio-Oncology- JAMA Network Open

Commentary on Twitter

Anthracycline is linked to double the rate of heart failure in patients with cancer vs matched controls, 7.4% at 15 years. https://t.co/SxlJkJ7oLR

— JAMA Network Open (@JAMANetworkOpen) February 3, 2023

Review | Dead space ventilation-related indices: bedside tools to evaluate the ventilation and perfusion relationship in patients with ARDS

6 Feb, 2023 | 13:18h | UTC

Dead space ventilation-related indices: bedside tools to evaluate the ventilation and perfusion relationship in patients with acute respiratory distress syndrome – Critical Care

Detection of pro-ictal state in human temporal lobe epilepsy

6 Feb, 2023 | 13:16h | UTC

Pro-Ictal State in Human Temporal Lobe Epilepsy – NEJM Evidence

MRI of diffuse-type tenosynovial giant cell tumor in the knee: a guide for diagnosis and treatment response assessment

6 Feb, 2023 | 13:15h | UTC

MRI of diffuse-type tenosynovial giant cell tumour in the knee: a guide for diagnosis and treatment response assessment – Insights into Imaging

M-A | Effect of early childhood development interventions to improve cognitive outcomes in children at 0–36 months

6 Feb, 2023 | 13:14h | UTC

Effect of early childhood development interventions delivered by healthcare providers to improve cognitive outcomes in children at 0–36 months: a systematic review and meta-analysis – Archives of Disease in Childhood (free for a limited period)

M-A | Cardiac resynchronization may improve outcomes in patients with intraventricular conduction delay but not in those with RBBB

6 Feb, 2023 | 13:13h | UTC

Cardiac Resynchronization Therapy Improves Outcomes in Patients With Intraventricular Conduction Delay But Not Right Bundle Branch Block: A Patient-Level Meta-Analysis of Randomized Controlled Trials – Circulation (free for a limited period)

Commentary: CRT Likely Benefits Broader Group of Patients: Meta-analysis – TCTMD

Commentary on Twitter

#OriginalResearch: In this patient level meta-analysis of RCTs, #CRT was associated with better outcomes in patients with QRS ≥150ms and IVCD or LBBB, but not RBBB @DanFriedmanMD @DrMGold1 @AnneBCurtis @VKutyifa @FudimMarat @F_dalgaard https://t.co/ptW1u9Op1E pic.twitter.com/qBxbiMxz4S

— Circulation (@CircAHA) February 1, 2023

Rates of antimicrobial resistance in Helicobacter pylori isolates across the US and Europe

6 Feb, 2023 | 13:12h | UTC

Rates of Antimicrobial Resistance in Helicobacter pylori Isolates From Clinical Trial Patients Across the US and Europe – The American Journal of Gastroenterology

Commentary: Time to ditch clarithromycin for H. pylori? – MDedge

Commentary on Twitter

New #RedJournal study by Mégraud, et al., shows high antibiotic resistance rates in #Hpylori isolates across the US & EU and the need for antibiotic resistance surveillance and novel treatment strategies for H. pylori.

? Read more: https://t.co/JT6P0MnEdW @umfoodoc @cwhowden pic.twitter.com/5FeV3Wj6Dw

— AJG – The American Journal of Gastroenterology (@AmJGastro) November 14, 2022