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Daily Archives: November 21, 2022

RCT | Intermittently scanned continuous glucose monitoring vs. fingerstick testing for Type 1 DM.

21 Nov, 2022 | 14:45h | UTC

RCT | Intermittently scanned continuous glucose monitoring vs. fingerstick testing for Type 1 DM. 

Intermittently Scanned Continuous Glucose Monitoring for Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text) 

Commentary: Continuous Monitoring Outperforms Fingerstick Testing in Patients With T1D, High Glycated Hemoglobin – AJMC 

 

Commentary on Twitter 

 


RCT | The effects of modifying amount and type of dietary carbohydrate on esophageal reflux symptoms.

21 Nov, 2022 | 14:42h | UTC

The Effects of Modifying Amount and Type of Dietary Carbohydrate on Esophageal Acid Exposure Time and Esophageal Reflux Symptoms: A Randomized Controlled Trial – The American Journal of Gastroenterology 

Commentary: Study finds that reducing intake of simple sugars improves GERD – Vanderbilt University 

 


RCT | NIV is superior to high-flow nasal cannula to prevent reintubation in patients at high risk for extubation failure.

21 Nov, 2022 | 14:41h | UTC

Effect of postextubation noninvasive ventilation with active humidification vs high-flow nasal cannula on reintubation in patients at very high risk for extubation failure: a randomized trial – Intensive Care Medicine (free for a limited period) 

 

Commentary on Twitter 

 

 


Cluster RCT | A personalized cooler dialysate provides no benefit for patients receiving maintenance hemodialysis.

21 Nov, 2022 | 14:38h | UTC

Personalised cooler dialysate for patients receiving maintenance haemodialysis (MyTEMP): a pragmatic, cluster-randomised trial – The Lancet (link to abstract – $ for full-text) 

Commentary: Clinical trial examines optimal dialysis temperature – University of Western Ontario 

 

Commentary on Twitter (thread – click for more) 

 


M-A | Global monkeypox case hospitalization rates.

21 Nov, 2022 | 14:36h | UTC

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine 

Related: 

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet 

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine 

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox. 

Monkeypox – New England Journal of Medicine 

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine 

Monkeypox: disease epidemiology, host immunity and clinical interventions. 

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health 

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain. 

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US. 

Update on the Monkeypox Outbreak – JAMA 

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases 

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ 

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch 

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine 

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases 

 


Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series.

21 Nov, 2022 | 14:35h | UTC

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet 

Commentaries: 

First study of monkeypox infection in women provides new insights to inform public health response to ongoing outbreak – Queen Mary University of London 

Study describes monkeypox in women; CDC warns of Tpoxx resistance – CIDRAP 

Related: 

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine 

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine 

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox. 

Monkeypox – New England Journal of Medicine 

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine 

Monkeypox: disease epidemiology, host immunity and clinical interventions. 

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health 

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain. 

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US. 

Update on the Monkeypox Outbreak – JAMA 

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases 

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ 

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch 

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine 

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases 

 


Cohort Study | Association of antidepressant use during pregnancy with risk of neurodevelopmental disorders in children.

21 Nov, 2022 | 14:33h | UTC

Association of Antidepressant Use During Pregnancy With Risk of Neurodevelopmental Disorders in Children – JAMA Internal Medicine (link to abstract – $ for full-text) 

Commentaries: 

Antidepressant Use During Pregnancy Not Associated With Neurodevelopmental Risk in Children – Psychiatric News Alert 

Antidepressants in Pregnancy Do Not Affect Child Neurodevelopment – HealthDay 

 

Commentary on Twitter 

https://twitter.com/JAMAInternalMed/status/1593046260440776704 

 


International guidelines and consensus on the use of lung ultrasound.

21 Nov, 2022 | 14:30h | UTC

New International Guidelines and Consensus on the Use of Lung Ultrasound – Journal of Ultrasound Medicine 

 


SR | Exercise for acutely hospitalized older medical patients.

21 Nov, 2022 | 14:28h | UTC

Exercise for acutely hospitalised older medical patients – Cochrane Library 

Summary: Exercise for older patients during unplanned hospital stays – Cochrane Library 

 

Commentary on Twitter 

https://twitter.com/CochraneUK/status/1593169319881756672 

 


Quick Guide for Radiation Oncologists | Everything you always wanted to know about sarcopenia but were afraid to ask.

21 Nov, 2022 | 14:29h | UTC

Everything You Always Wanted to Know about Sarcopenia but Were Afraid to Ask: A Quick Guide for Radiation Oncologists (impAct oF saRcopeniA In raDiotherapy: The AFRAID Project) – Current Oncology 

 


Review | Penetrating brain injury: ethical quandaries in the trauma bay and beyond.

21 Nov, 2022 | 14:25h | UTC

Review Paper on Penetrating Brain Injury: Ethical Quandaries in the Trauma Bay and Beyond – Annals of Surgery (free for a limited period) 

 


RCT | Quality of recovery with low-pressure vs. standard-pressure pneumoperitoneum during laparoscopic colorectal surgery.

21 Nov, 2022 | 14:23h | UTC

Quality of Recovery and Innate Immune Homeostasis in Patients Undergoing Low-pressure Versus Standard-pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery (RECOVER): A Randomized Controlled Trial – Annals of Surgery (free for a limited period) 

 


Expert consensus on liver transplantation perioperative evaluation and rehabilitation for acute-on-chronic liver failure.

21 Nov, 2022 | 14:21h | UTC

Expert consensus on liver transplantation perioperative evaluation and rehabilitation for acute-on-chronic liver failure – Liver Research 

 


RCT | Comparison between different corticosteroid injection techniques in adhesive capsulitis.

21 Nov, 2022 | 14:18h | UTC

Comparison Between Corticosteroid Injection Into Coracohumeral Ligament and Inferior Glenohumeral Capsule and Corticosteroid Injection Into Posterior Glenohumeral Recess in Adhesive Capsulitis: A Prospective Randomized Trial – Pain Physician (PDF) 

 


Portopulmonary hypertension: current developments and future perspectives.

21 Nov, 2022 | 14:20h | UTC

Portopulmonary hypertension: Current developments and future perspectives – Liver Research 

Related: Pulmonary complications in liver disease – Intensive Care Medicine (free) 

Related Reviews:  

Hepatopulmonary syndrome and portopulmonary hypertension: recent knowledge in pathogenesis and overview of clinical assessment – Liver International 

Pulmonary complications of hepatic diseases – World Journal of Gastroenterology 

Pulmonary Vascular Complications of Liver Disease – American Journal of Respiratory and Critical Care Medicine 

 


M-A | Lower vs. higher exposure to vasopressor therapy in vasodilatory hypotension.

21 Nov, 2022 | 14:16h | UTC

Lower Versus Higher Exposure to Vasopressor Therapy in Vasodilatory Hypotension: A Systematic Review With Meta-Analysis – Critical Care Medicine 

 


Epidemiology of ICU-onset bloodstream infection: prevalence, pathogens, and risk factors among 150,948 ICU patients.

21 Nov, 2022 | 14:14h | UTC

Epidemiology of ICU-Onset Bloodstream Infection: Prevalence, Pathogens, and Risk Factors Among 150,948 ICU Patients at 85 U.S. Hospitals* – Critical Care Medicine 

 


M-A | Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders.

21 Nov, 2022 | 14:11h | UTC

Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders: An umbrella review of randomised controlled trials and an updated meta-analysis – BJOG 

 

Commentary on Twitter 

https://twitter.com/BJOGTweets/status/1578676322095742977 

 


Review | Complications associated with venovenous extracorporeal membrane oxygenation—what can go wrong?

21 Nov, 2022 | 14:12h | UTC

Complications Associated With Venovenous Extracorporeal Membrane Oxygenation—What Can Go Wrong? – Critical Care Medicine 

 


Single-arm tumor-agnostic study | Avelumab plus Talazoparib in patients with BRCA1/2- or ATM-Altered advanced solid tumors.

21 Nov, 2022 | 14:07h | UTC

Avelumab Plus Talazoparib in Patients With BRCA1/2- or ATM-Altered Advanced Solid Tumors: Results From JAVELIN BRCA/ATM, an Open-Label, Multicenter, Phase 2b, Tumor-Agnostic Trial – JAMA Oncology 

 


M-A | Cardiac and kidney adverse effects of HIF Prolyl-Hydroxylase inhibitors for anemia in patients with CKD not receiving dialysis.

21 Nov, 2022 | 14:03h | UTC

Cardiac and Kidney Adverse Effects of HIF Prolyl-Hydroxylase Inhibitors for Anemia in Patients With CKD Not Receiving Dialysis: A Systematic Review and Meta-analysis – American Journal of Kidney Diseases 

 


Guide to statistics and methods | Adjustment for baseline characteristics in randomized clinical trials.

21 Nov, 2022 | 14:05h | UTC

Adjustment for Baseline Characteristics in Randomized Clinical Trials – JAMA (free for a limited period) 

Commentary: Should you adjust for baseline characteristics within randomized controlled trials? – Healthcare Economist 

 


M-A | Prophylactic platelet transfusions vs. no prophylaxis in hospitalized patients with thrombocytopenia.

21 Nov, 2022 | 13:59h | UTC

Prophylactic platelet transfusions versus no prophylaxis in hospitalized patients with thrombocytopenia: A systematic review with meta-analysis – Transfusion 

 


Cohort Study | Demographic, reproductive, and medical risk factors for intrauterine device expulsion.

21 Nov, 2022 | 13:57h | UTC

Demographic, Reproductive, and Medical Risk Factors for Intrauterine Device Expulsion – Obstetrics & Gynecology 

 


M-A | Epidemiology of persistent postoperative opioid use after cardiac surgery.

21 Nov, 2022 | 13:36h | UTC

Epidemiology of persistent postoperative opioid use after cardiac surgery: a systematic review and meta-analysis – British Journal of Anaesthesia 

 


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