Daily Archives: November 17, 2022 | LinksMedicus Free Medical News & Perspectives

RCT | Clopidogrel is better than Aspirin for chronic maintenance monotherapy after percutaneous coronary intervention.

17 Nov, 2022 | 12:30h | UTC

Aspirin vs. Clopidogrel for Chronic Maintenance Monotherapy after Percutaneous Coronary Intervention: the HOST-EXAM Extended Study – Circulation

Meta-analysis of randomized trials: Clopidogrel is better than aspirin for the secondary prevention of cardiovascular events.

#ACC21 – RCT: Clopidogrel better than aspirin for chronic maintenance monotherapy after percutaneous coronary intervention.

Commentary on Twitter

https://twitter.com/CircAHA/status/1589647384073703426

Guideline | Management of castration-resistant prostate cancer.

17 Nov, 2022 | 12:28h | UTC

2022 Canadian Urological Association (CUA)-Canadian Uro Oncology Group (CUOG) guideline: Management of castration-resistant prostate cancer (CRPC) – Canadian Urological Association Journal

Sudden cardiac death in the young: a consensus statement on recommended practices for cardiac examination by the pathologist.

17 Nov, 2022 | 12:27h | UTC

Sudden Cardiac Death in the Young: A Consensus Statement on Recommended Practices for Cardiac Examination by the Pathologist from the Society for Cardiovascular Pathology – Cardiovascular Pathology

M-A | High-flow nasal cannula vs. non-invasive ventilation for acute hypercapnic respiratory failure in adults.

17 Nov, 2022 | 12:25h | UTC

High-flow nasal cannula versus non-invasive ventilation for acute hypercapnic respiratory failure in adults: a systematic review and meta-analysis of randomized trials – Critical Care

Phase 2b RCT | Rituximab vs. IV cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease.

17 Nov, 2022 | 12:24h | UTC

Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial – The Lancet Respiratory Medicine

Commentaries:

RECITAL: Rituximab represents alternative to cyclophosphamide for CTD-ILD – medwire News

CTD-ILD: Rituximab ‘a Reasonable Alternative to Cyclophosphamide’ – Medscape (free registration required)

Commentary on Twitter

https://twitter.com/LancetRespirMed/status/1592057243075112960

Phase 2 RCT | Efficacy and safety of low-dose Interleukin 2 for primary Sjögren syndrome.

17 Nov, 2022 | 12:20h | UTC

Efficacy and Safety of Low-Dose Interleukin 2 for Primary Sjögren Syndrome: A Randomized Clinical Trial – JAMA Network Open

Commentary: Sjogren’s Responds to Cytokine Treatment, Early Data Show — Phase II trial signals possible breakthrough for hard-to-treat illness – MedPage Today (free registration required)

RCT | Safety of withholding perioperative hydrocortisone for patients with pituitary adenomas with an intact HPA axis.

17 Nov, 2022 | 12:23h | UTC

Safety of Withholding Perioperative Hydrocortisone for Patients With Pituitary Adenomas With an Intact Hypothalamus-Pituitary-Adrenal Axis: A Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

https://twitter.com/JAMANetworkOpen/status/1592940564433059840

RCT | Extending the duration of prequit treatment with varenicline did not increase smoking abstinence rates.

17 Nov, 2022 | 12:22h | UTC

Effect of Extending the Duration of Prequit Treatment With Varenicline on Smoking Abstinence: A Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

https://twitter.com/JAMANetworkOpen/status/1591128623947591680

Consistency between trials presented at conferences, their subsequent publications and press releases.

17 Nov, 2022 | 12:19h | UTC

Consistency between trials presented at conferences, their subsequent publications and press releases – BMJ Evidence-Based Medicine

Mild-to-moderate kidney dysfunction and cardiovascular disease: observational and mendelian randomization analyses.

17 Nov, 2022 | 12:18h | UTC

Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses – Circulation

Commentary on Twitter

https://twitter.com/CircAHA/status/1587897418989080577

Crossover RCT | Spectacle lenses with highly aspherical lenslets for slowing myopia.

17 Nov, 2022 | 12:16h | UTC

Spectacle lenses with highly aspherical lenslets for slowing myopia: A randomised, double-blind, cross-over clinical trial – American Journal of Ophthalmology

RCT: Spectacle lenses with aspherical lenslets for myopia control vs. single-vision spectacle lenses.

Randomized trial: Effect of High add power, medium add power, or single-vision contact lenses on myopia progression in children

M-A | Mechanical thrombectomy in acute basilar artery stroke.

17 Nov, 2022 | 12:13h | UTC

Mechanical thrombectomy in acute basilar artery stroke: a systematic review and Meta-analysis of randomized controlled trials – BMC Neurology

RCTs | Thrombectomy improved recovery in basilar artery stroke but increased procedural complications and hemorrhages.

Registry-based cohort study: Endovascular treatment vs. best medical management in acute basilar artery occlusion strokes.

RCT: Endovascular therapy for stroke due to basilar-artery occlusion – “endovascular therapy and medical therapy did not differ significantly with respect to a favorable functional outcome”.

Commentary on Twitter

https://twitter.com/drjkwan/status/1590403041840467969

Inclisiran and cardiovascular events: a patient-level analysis of phase III trials.

17 Nov, 2022 | 12:17h | UTC

Inclisiran and cardiovascular events: a patient-level analysis of phase III trials – European Heart Journal

Commentary: Inclisiran and Cardiovascular Events – American College of Cardiology

Commentary on Twitter

https://twitter.com/ESC_Journals/status/1592113799481692162

Review | Prostate-specific antigen screening in transgender patients.

17 Nov, 2022 | 12:12h | UTC

Prostate-Specific Antigen Screening in Transgender Patients – European Urology

Commentary on Twitter

https://twitter.com/EUplatinum/status/1589594270046068736

RCT | The comparison of two different strategies of intravitreal conbercept for polypoidal choroidal vasculopathy.

17 Nov, 2022 | 12:11h | UTC

The comparison of two different strategies of intravitreal conbercept for polypoidal choroidal vasculopathy in Chinese patients results from a 48-week randomized phase 4 study: STAR study – Acta Ophthalmologica

Commentary: Quarterly Dosing of Conbercept Similar to Treat-and-Extend Regimen for PCV – HCP Live

M-A | Comparative accuracy of biomarkers for predicting hospital-acquired acute kidney injury.

17 Nov, 2022 | 12:09h | UTC

Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis – Critical Care

Review | POCUS for aortic dissection in the clinical presentation of ischemic stroke.

17 Nov, 2022 | 12:08h | UTC

POCUS for aortic dissection in the clinical presentation of ischemic stroke – emDocs

SR | Mosquito aquatic habitat modification and manipulation interventions to control malaria.

17 Nov, 2022 | 12:06h | UTC

Mosquito aquatic habitat modification and manipulation interventions to control malaria – Cochrane Library

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