Daily Archives: November 10, 2022
WHO Report | A blueprint for dementia research.
10 Nov, 2022 | 14:17h | UTCA blueprint for dementia research – World Health Organization
News Release: Launch of WHO’s first blueprint for dementia research – World Health Organization
Commentary on Twitter (thread – click for more)
#Dementia is one of the greatest health challenges of our generation. By the end of this decade, 7⃣8⃣ million people will be living with dementia.
WHO's 🆕 blueprint for dementia research sets much needed guidelines to drive innovation to beat dementia ⬇️
— World Health Organization (WHO) (@WHO) October 4, 2022
NICE Guideline Update | Colonoscopic surveillance in adults with inflammatory bowel disease or adenomas.
10 Nov, 2022 | 14:16h | UTCRelated:
USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.
ACG Clinical Guidelines: Start colorectal cancer screening at 45
RCT | Intermediate-dose no better than low-dose LMWH in pregnant and post-partum women with previous thromboembolism.
10 Nov, 2022 | 14:12h | UTCIntermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary from the author on Twitter (thread – click for more)
Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial https://t.co/9zHeUIda7o
— Saskia Middeldorp (@MiddeldorpS) October 28, 2022
RCT | Monofilament suture is no better than braided suture to improve pregnancy outcomes after vaginal cervical cerclage.
10 Nov, 2022 | 14:14h | UTCInvited Commentary: Suture choice for cervical cerclage – The Lancet (free registration required)
News Release: Single stranded suture threads could prevent pregnancy infection complications, C-STICH trial finds – University of Birmingham
Video Summary: Major trial finds purse-string wire in surgery can reduce miscarriage and stillbirth – University of Birmingham
Commentary: Monofilament Suture Not Superior for Vaginal Cervical Cerclage – HealthDay
Commentary on Twitter (thread – click for more)
Vaginal cervical cerclage is performed to prevent pregnancy loss and preterm birth.
In this trial, researchers assessed the effect on pregnancy loss of using a monofilament suture thread compared with braided suture thread: https://t.co/kBgGGn5D4L
— The Lancet (@TheLancet) October 27, 2022
Study | In hypertensive disorders of pregnancy, the levels of angiogenic factors may stratify the risk of severe preeclampsia.
10 Nov, 2022 | 14:11h | UTCCirculating Angiogenic Factor Levels in Hypertensive Disorders of Pregnancy – NEJM Evidence
Commentary on Twitter
This study measured the ratio of serum soluble fms-like tyrosine kinase (sFlt-1) to placental growth factor (PIGF) in pregnant pts hospitalized with HTN. An sFLT-1:PIGF ratio ≥ 40 stratified the risk of progressing to severe pre-eclampsia within 2 wks. https://t.co/H0uSHT2bN7 pic.twitter.com/ZKRvHsqLA4
— NEJM Evidence (@NEJMEvidence) November 9, 2022
RCT | Mindfulness-based stress reduction vs. escitalopram for the treatment of adults with anxiety disorders.
10 Nov, 2022 | 14:09h | UTCMindfulness-Based Stress Reduction vs Escitalopram for the Treatment of Adults With Anxiety Disorders: A Randomized Clinical Trial – JAMA Psychiatry (free for a limited period)
Commentaries:
Mindfulness worked as well for anxiety as drug in study – Associated Press
Meditation works as well as a popular drug to reduce anxiety, study finds – NPR
Commentary on Twitter
This randomized, controlled #anxiety disorder treatment trial comparing a standardized, evidence-based mindfulness-based intervention with pharmacotherapy and found that mindfulness based stress reduction was non-inferior to escitalopram https://t.co/P7KJQlT03g
— JAMA Psychiatry (@JAMAPsych) November 9, 2022
Cohort Study | Study shows subclinical Hyperthyroidism is linked to an increased risk of fractures.
10 Nov, 2022 | 14:08h | UTCAssociation Between Subclinical Thyroid Dysfunction and Fracture Risk – JAMA Network Open
Commentary: Does Subclinical Hyperthyroidism Raise Fracture Risk? – Medscape (free registration required)
Commentary on Twitter
Subclinical hyperthyroidism may be an independent risk factor associated with fracture, highlighting a potential role for more aggressive screening and monitoring to prevent bone mineral disease. #OAReasearch https://t.co/LQVjaNU1zM
— JAMA Network Open (@JAMANetworkOpen) November 8, 2022
On the natural history of coronary artery disease: a longitudinal nationwide serial angiography study.
10 Nov, 2022 | 14:03h | UTC
RCT | Tamponade dressing does not reduce bleeding or pain compared to no dressing after hemorrhoidectomy.
10 Nov, 2022 | 14:06h | UTC
Commentary on Twitter
What's the role of tamponade dressing after #haemorrhoidectomy?
RCT 🇩🇪 725 patients
Tamponade dressing assoc w:
🔼pain
🟰 bleeding ratesWhy use it?#some4surgery #colorectalsurgery@Mcfark @LauraLorenzonMD @paulo_sutt https://t.co/J4bA3uSowT pic.twitter.com/Cda7ibx2rd
— BJS Open (@BjsOpen) June 2, 2022
Cohort Study | Surveillance of long-term outcomes of devices after endovascular abdominal aortic aneurysm repair.
10 Nov, 2022 | 14:00h | UTC
Commentary on Twitter
https://twitter.com/bmj_latest/status/1584922859822014466
Editorial | The urgent need to recognize and properly address prenatal-onset group B Streptococcus disease.
10 Nov, 2022 | 13:59h | UTC
M-A | Bioresorbable vascular scaffolds are inferior compared to conventional drug-eluting stents across time.
10 Nov, 2022 | 13:57h | UTC
Commentary on Twitter
Bioresorbable vascular scaffolds #BVS vs. conventional drug-eluting stents #DES across time:
A #metaanalysis of RCTs@banerjeep https://t.co/XyDVI7XNMi pic.twitter.com/AjEPC6Zv3E— Open Heart (@Open_HeartBMJ) October 27, 2022
RCT | Effect of local anesthetic infiltration on postoperative pain after laparoscopic cholecystectomy.
10 Nov, 2022 | 13:56h | UTC
Commentary on Twitter
Does it matter where you put local #anasthetic after #lapchole?
This #RCT 🇹🇭 shows that getting the local into the sheath, not just skin, reduces pain.#some4surgery #surgicalresearchhttps://t.co/ByRt7zuLfR@asgbi @SEIQuirurgica @villesallinen @Gio_Marchegiani pic.twitter.com/Cszf9H2wO2
— BJS Open (@BjsOpen) June 3, 2022
RCT | Effects of a narrative-based psychoeducational intervention to prepare patients for responding to acute MI.
10 Nov, 2022 | 13:51h | UTC
RCT | Transbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases.
10 Nov, 2022 | 13:54h | UTCTransbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases: a multicentre, open-label, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW—Mediastinal cryobiopsy + standard EBUS-TBNA = significant improvement in diagnostic yield for mediastinal lesions. This combined approach is a valid first-line diagnostic tool for mediastinal diseases.
Study from Prof Felix Herth, & colleagues https://t.co/DGJCrKVDbI pic.twitter.com/cvG89hNIHS
— The Lancet Respiratory Medicine (@LancetRespirMed) October 24, 2022
Case-control study | Risk variants in the exomes of children with critical illness.
10 Nov, 2022 | 13:52h | UTCRisk Variants in the Exomes of Children With Critical Illness – JAMA Network Open
Cohort Study | Systemic lupus erythematosus low disease activity and mortality risk.
10 Nov, 2022 | 13:48h | UTCLupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort study – The Lancet Rheumatology (link to abstract – $ for full-text)
Commentary on Twitter
NEW RESEARCH—Lupus low disease activity state (#LLDAS) significantly reduced the risk of mortality in patients with #SLE; remission did not further reduce the risk of mortality unless lower glucocorticoid thresholds were used https://t.co/xYqzQME3li #LupusAwarenessMonth pic.twitter.com/gtLTKn92Go
— The Lancet Rheumatology (@TheLancetRheum) October 24, 2022
Associations between social connections and cognition: a global collaborative individual participant data meta-analysis.
10 Nov, 2022 | 13:44h | UTCNews Release: Living with others and community engagement are keys to reduced dementia risk – University of New South Wales
Commentary on Twitter (thread – click for more)
Our paper on associations between social health and cognitive decline led by @samtani_suraj in the SHARED consortium https://t.co/nZ9JKSY8Pg is now out in Lancet Healthy Longev followed by a brilliant commentary by Dr. Adam Roth at @OkStateSocio https://t.co/QVbG4IG4u3
— Anna Marseglia (@anna_marseglia_) October 21, 2022
The global, regional, and national burden of benign prostatic hyperplasia in 204 countries and territories from 2000 to 2019.
10 Nov, 2022 | 13:43h | UTCInvited Commentary: Benign prostatic hyperplasia: a global challenge of the ageing population – The Lancet Health Longevity
Review | Equal but different! Improving care for older LGBT+ adults.
10 Nov, 2022 | 13:39h | UTCEqual but different! Improving care for older LGBT+ adults – Age and Ageing (free for a limited period)
Review | New horizons in the ageing autonomic nervous system: orthostatic hypotension and supine hypertension.
10 Nov, 2022 | 13:37h | UTC
RCT | Preoperative ultrasound-guided percutaneous cryoneurolysis for the treatment of pain after mastectomy.
10 Nov, 2022 | 13:41h | UTCInfographic: Tip of the Iceberg: The History of Cryoneurolysis – Anesthesiology
RCT | Prophylactic tranexamic acid did not decrease bleeding in patients with hematologic malignancy.
10 Nov, 2022 | 13:36h | UTCCommentary: Tranexamic Acid (TXA) Prophylaxis in Patients with Hematologic Malignancies – Physician’s Weekly
Retrospective Cohort Study | Trends, predictors, and outcomes of CV complications at delivery associated with gestational diabetes.
10 Nov, 2022 | 13:34h | UTC
Commentary on Twitter
https://twitter.com/ErinMichos/status/1586008508331266048
Effective cataract surgical coverage in adults aged 50 years and older: estimates from population-based surveys in 55 countries.
10 Nov, 2022 | 13:32h | UTC
Commentary on Twitter
And Effective cataract surgical coverage in adults aged 50 years and older: estimates from population-based surveys in 55 countries https://t.co/nRMUu2vUI4 (2/2) pic.twitter.com/5E7X2eZtp1
— The Lancet Global Health (@LancetGH) October 13, 2022


