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Daily Archives: September 29, 2022

RCT | In patients with Type 1 Diabetes, the use of a “bionic pancreas” reduced HbA1c without increasing hypoglycemia.

29 Sep, 2022 | 13:35h | UTC

Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Bionic pancreas improves type 1 diabetes management compared to standard insulin delivery methods – National Institutes of Health

 


Cohort Study | Determinants of drug-coated balloon failure in patients undergoing femoropopliteal arterial intervention.

29 Sep, 2022 | 13:33h | UTC

Determinants of Drug-Coated Balloon Failure in Patients Undergoing Femoropopliteal Arterial Intervention – Journal of the American College of Cardiology

 


Review | Treatment and prevention of heat-related illness.

29 Sep, 2022 | 13:34h | UTC

Treatment and Prevention of Heat-Related Illness

Related:

Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Heat Illness: 2019 Update

ACSM Expert Consensus Statement on Exertional Heat Illness: Recognition, Management, and Return to Activity

 

Commentary on Twitter

 


RCT | Abbreviated antiplatelet therapy after coronary stenting in patients with myocardial infarction at high bleeding risk.

29 Sep, 2022 | 13:32h | UTC

Abbreviated Antiplatelet Therapy After Coronary Stenting in Patients With Myocardial Infarction at High Bleeding Risk – Journal of the American College of Cardiology

Original publication: #ESCCongress – RCT: In patients who underwent PCI at high bleeding risk, 1 month of dual antiplatelet therapy was noninferior to the continuation of dual therapy for at least 2 additional months and resulted in a lower incidence of bleeding events.

 


WGO Guideline—Endoscope disinfection update.

29 Sep, 2022 | 13:31h | UTC

WGO Guideline—Endoscope Disinfection Update – Journal of Clinical Gastroenterology

 


European Crohn’s and Colitis Guidelines on sexuality, fertility, pregnancy, and lactation.

29 Sep, 2022 | 13:30h | UTC

European Crohn’s and Colitis Guidelines on Sexuality, Fertility, Pregnancy, and Lactation – Journal of Crohn’s and Colitis

 


RCT | Effect of Dimethyl Fumarate vs. Interferon Beta-1a in patients with pediatric-onset multiple sclerosis.

29 Sep, 2022 | 13:29h | UTC

Effect of Dimethyl Fumarate vs Interferon β-1a in Patients With Pediatric-Onset Multiple Sclerosis: The CONNECT Randomized Clinical Trial – JAMA Network Open

Invited Commentary: Considering the Future of Pediatric Multiple Sclerosis Trials After the CONNECT Open-Label Randomized Trial – JAMA Network Open

See also: Visual Abstract

 


Viewpoint | Using behavioral economics to decrease operating room costs and promote better surgeon accountability.

29 Sep, 2022 | 13:28h | UTC

Using Behavioral Economics to Decrease Operating Room Costs and Promote Better Surgeon Accountability – JAMA Surgery (free for a limited period)

 


Temporal association between invasive procedures and infective endocarditis.

29 Sep, 2022 | 13:26h | UTC

Temporal association between invasive procedures and infective endocarditis – Heart

 


Perspective | Same-day discharge after minimally invasive colectomy.

29 Sep, 2022 | 13:27h | UTC

Same-Day Discharge After Minimally Invasive Colectomy – JAMA Surgery (free for a limited period)

 


How applicable is the single-dose AMBITION regimen for HIV-associated cryptococcal meningitis to high-income settings?

29 Sep, 2022 | 13:26h | UTC

How applicable is the single-dose AMBITION regimen for HIV-associated cryptococcal meningitis to high-income settings? – Clinical Infectious Diseases

 

Commentary on Twitter

Under a https://creativecommons.org/licenses/by/4.0/ license

 


Phase 1 study | GPRC5D-Targeted CAR T Cells for patients with heavily pretreated Multiple Myeloma.

29 Sep, 2022 | 13:25h | UTC

GPRC5D-Targeted CAR T Cells for Myeloma – New England Journal of Medicine (link to abstract – $ for full-text)

 


M-A | Carbon dioxide laser vs. vaginal estrogen for genitourinary syndrome of menopause.

29 Sep, 2022 | 13:24h | UTC

Comparison of Severity of Genitourinary Syndrome of Menopause Symptoms After Carbon Dioxide Laser vs Vaginal Estrogen Therapy: A Systematic Review and Meta-analysis – JAMA Network Open

Related: RCT: Laser treatment not better than sham treatment on symptom severity in women with postmenopausal vaginal symptoms.

 

Commentary on Twitter

 


RCT | ShangRing vs. Mogen clamp for early infant male circumcision in eastern sub-Saharan Africa.

29 Sep, 2022 | 13:23h | UTC

ShangRing versus Mogen clamp for early infant male circumcision in eastern sub-Saharan Africa: a multicentre, non-inferiority, adaptive, randomised controlled trial – The Lancet Global Health

Invited Commentary: Can the ShangRing bring us closer to endorsing early infant male circumcision in sub-Saharan Africa? – The Lancet Global Health

 


RCT | Pembrolizumab vs. placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer.

29 Sep, 2022 | 13:22h | UTC

Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentaries:

Adjuvant Pembrolizumab in Patients With Completely Resected Stage IB to IIIA NSCLC – The ASCO Post

Adjuvant Pembrolizumab Prolongs DFS in Resected Non-Small Cell Lung Cancer – Cancer Therapy Advisor

 

Commentary on Twitter

 


RCT | Immunogenicity and safety of one-dose human papillomavirus vaccine vs. two or three doses.

29 Sep, 2022 | 13:21h | UTC

Immunogenicity and safety of one-dose human papillomavirus vaccine compared with two or three doses in Tanzanian girls (DoRIS): an open-label, randomised, non-inferiority trial – The Lancet Global Health

Invited Commentary: HPV vaccines: when one plus one equals three – The Lancet Global Health

Related:

RCT: Single-dose HPV vaccination found effective among young African women.

Three-year follow-up of 2-dose versus 3-dose HPV vaccine

Opinion: A Single-dose HPV Vaccine Would Have a Big Impact on Cancer Prevention

Another Observational Study Suggests One Dose of HPV Vaccine may be Enough

Another Study Suggesting One Dose of HPV Vaccine may be Effective for Prevention of Cervical Cancer

Comparison of different human papillomavirus (HPV) vaccines and the number of doses administered to prevent HPV-related disease in females and males – Cochrane Library

Large Observational Study Suggests One Dose of HPV Vaccine May Be as Effective as Three

 


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