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Daily Archives: September 20, 2022

Long-term follow-up of a RCT | Percutaneous coronary intervention vs. bypass surgery for multivessel coronary artery disease.

20 Sep, 2022 | 13:34h | UTC

Everolimus-Eluting Stents or Bypass Surgery for Multivessel Coronary Artery Disease: Extended Follow-up Outcomes of Multicenter Randomized Controlled BEST Trial – Circulation

Commentary: 10-Year Data From BEST Trial Find No Significant Safety or MACE Differences Between PCI With EES Versus CABG – Cardiac Interventions Today

Original Study: Trial of Everolimus-Eluting Stents or Bypass Surgery for Coronary Disease – New England Journal of Medicine

 


Long-term follow-up of a RCT | Outcomes after catheter-based renal artery denervation for resistant hypertension.

20 Sep, 2022 | 13:33h | UTC

Long-term outcomes after catheter-based renal artery denervation for resistant hypertension: final follow-up of the randomised SYMPLICITY HTN-3 Trial – The Lancet (free registration required)

Commentary: SYMPLICITY HTN-3’s Late Surprise: Sustained BP Drop at 3 Years Despite Earlier Miss – TCTMD

Original Study: A Controlled Trial of Renal Denervation for Resistant Hypertension – New England Journal of Medicine

 


RCT | Myopia control effect of repeated low-level red-light therapy in children.

20 Sep, 2022 | 13:31h | UTC

Myopia Control Effect of Repeated Low-Level Red-Light Therapy in Chinese Children: A Randomized, Double-Blind, Controlled Clinical Trial – Ophthalmology

Commentary: Repeated Low-Level Red-Light Therapy Reduces Myopia Progression in Children – HCP Live

 


Brief Review | Source control in the management of sepsis and septic shock.

20 Sep, 2022 | 13:32h | UTC

Source control in the management of sepsis and septic shock – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Preliminary results of a RCT | Once-only colonoscopy vs. two rounds of fecal immunochemical testing 2 years apart for colorectal cancer screening.

20 Sep, 2022 | 13:29h | UTC

Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening (SCREESCO): preliminary report of a randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Two Rounds of FIT vs Single Colonoscopy as a One-time CRC Screening – Medscape (free registration required)

 


Network M-A | Associations between statins and adverse events in secondary prevention of cardiovascular disease.

20 Sep, 2022 | 13:30h | UTC

Associations between statins and adverse events in secondary prevention of cardiovascular disease: Pairwise, network, and dose-response meta-analyses of 47 randomized controlled trials – Frontiers in Cardiovascular Medicine

 


Consensus Paper | Pediatric robotic surgery: issues in management.

20 Sep, 2022 | 13:28h | UTC

Pediatric robotic surgery: issues in management—expert consensus from the Italian Society of Pediatric and Neonatal Anesthesia and Intensive Care (SARNePI) and the Italian Society of Pediatric Surgery (SICP) – Surgical Endoscopy

 


Guideline on pharmacological interventions for long-term secondary prevention after ischemic stroke or transient ischemic attack.

20 Sep, 2022 | 13:27h | UTC

European Stroke Organisation (ESO) guideline on pharmacological interventions for long-term secondary prevention after ischaemic stroke or transient ischaemic attack – European Stroke Journal (free for a limited period)

 


Guidelines on treatment of patients with intracranial atherosclerotic disease.

20 Sep, 2022 | 13:26h | UTC

European Stroke Organisation guidelines on treatment of patients with intracranial atherosclerotic disease – European Stroke Journal (free for a limited period)

 


Guidelines on management of unruptured intracranial aneurysms.

20 Sep, 2022 | 13:25h | UTC

European Stroke Organisation (ESO) guidelines on management of unruptured intracranial aneurysms – European Stroke Journal (free for a limited period)

 


Guideline on screening for subclinical atrial fibrillation after stroke or transient ischemic attack of undetermined origin.

20 Sep, 2022 | 13:25h | UTC

European Stroke Organisation (ESO) guideline on screening for subclinical atrial fibrillation after stroke or transient ischaemic attack of undetermined origin – European Stroke Journal (free for a limited period)

 


M-A of randomized trials | Hyperthermic intraperitoneal chemotherapy (HIPEC) for the management of primary advanced and recurrent ovarian cancer.

20 Sep, 2022 | 13:23h | UTC

Hyperthermic intraperitoneal chemotherapy (HIPEC) for the management of primary advanced and recurrent ovarian cancer: a systematic review and meta-analysis of randomized trials – ESMO Open

Related:

Survival After Hyperthermic Intraperitoneal Chemotherapy and Primary or Interval Cytoreductive Surgery in Ovarian Cancer: A Randomized Clinical Trial – JAMA Surgery

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer – New England Journal of Medicine

 


M-A of randomized trials | Effectiveness and cost-effectiveness of oral nutritional supplements in frail older people who are malnourished or at risk of malnutrition.

20 Sep, 2022 | 13:24h | UTC

Effectiveness and cost-effectiveness of oral nutritional supplements in frail older people who are malnourished or at risk of malnutrition: a systematic review and meta-analysis – The Lancet Health Longevity

Invited Commentary: Do oral nutritional supplements effectively reduce malnutrition or its adverse outcomes in older people with frailty? – The Lancet Health Longevity

 


RCT | Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis.

20 Sep, 2022 | 13:20h | UTC

Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet

Commentary: Dupilumab Eases Atopic Dermatitis in Children Younger Than 6 Years – HealthDay

 


Single-arm phase 1/2 study | Tumor-agnostic efficacy and safety of Selpercatinib in patients with RET fusion-positive solid tumors other than lung or thyroid tumors.

20 Sep, 2022 | 13:18h | UTC

Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open-label, basket trial – The Lancet Oncology

Invited Commentary: Tissue-agnostic RET inhibition: can you trust your target? – The Lancet Oncology

News Release: RET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population – University of Texas M. D. Anderson Cancer Center

 

Commentary from the author on Twitter (thread – click for more)

 


RCTs | Linzagolix with and without hormonal add-back therapy for the treatment of symptomatic uterine fibroids.

20 Sep, 2022 | 13:19h | UTC

Linzagolix with and without hormonal add-back therapy for the treatment of symptomatic uterine fibroids: two randomised, placebo-controlled, phase 3 trials – The Lancet

 


Case report and brief review | Severe thrombotic complications secondary to antiphospholipid syndrome and undiagnosed systemic lupus erythematosus.

20 Sep, 2022 | 13:17h | UTC

Severe thrombotic complications secondary to antiphospholipid syndrome and undiagnosed systemic lupus erythematosus – Canadian Medical Association Journal

 


RCT | Deucravacitinib vs. placebo and Apremilast in moderate to severe plaque psoriasis.

20 Sep, 2022 | 13:16h | UTC

Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: efficacy and safety results from the 52-week, randomized, double-blinded, phase 3 POETYK PSO-2 trial – Journal of the American Academy of Dermatology

 


A simple score to identify increased risk of transthyretin amyloid cardiomyopathy in heart failure with preserved ejection fraction.

20 Sep, 2022 | 13:16h | UTC

A Simple Score to Identify Increased Risk of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction – JAMA Cardiology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Evaluation of an ambulatory ECG analysis platform using deep neural networks in routine clinical practice.

20 Sep, 2022 | 13:14h | UTC

Evaluation of an Ambulatory ECG Analysis Platform Using Deep Neural Networks in Routine Clinical Practice – Journal of the American Heart Association

 

Commentary on Twitter

 


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