Daily Archives: September 14, 2022
USPSTF Statement | The current evidence is insufficient to recommend routine screening for prediabetes and type 2 diabetes in children and adolescents.
14 Sep, 2022 | 13:23h | UTCEditorials:
Recommendations for Screening Children and Adolescents for Prediabetes and Type 2 Diabetes – JAMA
Broader Screening for Youth-Onset Type 2 Diabetes—We Just Are Not There Yet – JAMA Network Open
Patient Page: Screening for Type 2 Diabetes in Children and Adolescents – JAMA
Author Interview: USPSTF Recommendation: Screening for Prediabetes and Diabetes in Children and Adolescents – JAMA
Study | Vitamin D3 and omega-3 fatty acids not helpful in reducing the risk of frailty.
14 Sep, 2022 | 13:20h | UTCNews Release: Vitamin D3 and omega-3 fatty acids not helpful in reducing risk of frailty – Brigham and Women’s Hospital
Invited Commentary: There Is No Magic Pill to Prevent Frailty—You Still Have to Eat Your Vegetables – JAMA Network Open
Commentary on Twitter
New findings from the VITAL trial do not support the routine use of vitamin D3 or omega-3 fatty acid supplementation in community-dwelling older adults for the prevention of frailty. #OAResearch https://t.co/LIJO8bJ0Wk #OAResearch
— JAMA Network Open (@JAMANetworkOpen) September 13, 2022
Cohort Study | Risk factors for heart disease and stroke are largely similar in men and women globally.
14 Sep, 2022 | 13:18h | UTCNews Release: Risk factors for heart disease and stroke are largely similar in men and women globally, finds study – McMaster University
Original Study: Metabolic, behavioural, and psychosocial risk factors and cardiovascular disease in women compared with men in 21 high-income, middle-income, and low-income countries: an analysis of the PURE study – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/TheLancet/status/1569636002762817536
RCT | Extended duration thromboprophylaxis (continued for 56 days postoperatively) is not beneficial after surgical resection of colorectal cancer.
14 Sep, 2022 | 13:22h | UTC
Cohort Study | Prospective associations of daily step counts and intensity with cancer and cardiovascular disease incidence and mortality and all-cause mortality.
14 Sep, 2022 | 13:17h | UTCCommentaries:
Higher Step Counts Equal Better CV Health: UK Biobank – TCTMD
Pace as important as 10,000 steps for health, finds new research – University of Sidney
How Many Steps a Day (and How Fast) to Lengthen Your Life? – HealthDay
Long-term follow-up of a RCT | Endoscopic versus surgical step-up approach for infected necrotizing pancreatitis.
14 Sep, 2022 | 13:13h | UTC
Commentary on Twitter
Long term follow-up #TENSION trial 🇳🇱, today @AGA_Gastro: Endoscopic step-up approach not superior to surgical step-up approach in pts with infected necrotizing #pancreatitis. With endoscopy: ⬇️ pancreaticocutaneous fistulas and ⬇️ re-interventions. https://t.co/WKP7Pwb3vG pic.twitter.com/CGgd3jiTxm
— Marc Besselink (@MarcBesselink) May 18, 2022
Under a Creative Commons Attribution (CC BY 4.0) License
M-A of randomized trials | In patients hospitalized with community-acquired pneumonia, corticosteroids reduce the need for mechanical ventilation without significant effects on mortality, treatment failure, or adverse events.
14 Sep, 2022 | 13:16h | UTCEffect of corticosteroids on mortality and clinical cure in community-acquired pneumonia: A systematic review, meta-analysis, and meta-regression of randomized control trials – CHEST Journal (link to abstract – $ for full-text)
Perspective | Redefining critical illness.
14 Sep, 2022 | 13:13h | UTCRedefining critical illness – Nature Medicine
Review | Multisystem inflammatory syndrome in children (MIS-C) and neonates (MIS-N) associated with COVID-19: optimizing definition and management.
14 Sep, 2022 | 13:15h | UTC
Commentary on Twitter
Proposed classification of Multisystem inflammatory syndrome in #neonates (MIS-N)
Clinical features
Treatment and immunological mechanisms#MISC #covid19 #PIMSTS #PedsICU#NeoEBM @DrSBagci #NeoTwitter #Neonatology @DrKenRemy1 @ChrisCarrollMD @lizWWyld https://t.co/tDuM51GMr4 pic.twitter.com/PNobOOzevX— Yonca Bulut M.D. (@yoncabulutmd) September 6, 2022
Under a http://creativecommons.org/licenses/by/4.0/ License
Systematic Review | Interventions for improving mobility after hip fracture surgery in adults.
14 Sep, 2022 | 13:11h | UTCInterventions for improving mobility after hip fracture surgery in adults – Cochrane Library
Commentary from the author on Twitter
Pleased to have our Cochrane review on mobility training after hip fracture out today. Key message “extra exercises targeting balance, walking and functional tasks appear effective in improving mobility in hospital and after discharge.” @msk_health https://t.co/vLbGWKZWgp
— Prof Cathie Sherrington (@CathieSherr) September 7, 2022
Systematic Review | Maternal postures for fetal malposition in labor for improving the health of mothers and their infants.
14 Sep, 2022 | 13:12h | UTCSummary: Mothers’ positions in labour when baby is lying ‘back-to-back’ – Cochrane Library
M-A | Antibiotic use in ambulatory care for acutely ill children in high-income countries.
14 Sep, 2022 | 13:10h | UTC
M-A of randomized trials | Digital health interventions for musculoskeletal pain conditions.
14 Sep, 2022 | 13:08h | UTC
Retrospective Cohort Study | Natural history of MYH7-related dilated cardiomyopathy.
14 Sep, 2022 | 13:06h | UTC
M-A of randomized trials | Effectiveness of work-related interventions for return to work in people on sick leave.
14 Sep, 2022 | 13:08h | UTC
Review | Nutritional support for pediatric severe traumatic brain injury.
14 Sep, 2022 | 13:04h | UTCNutritional Support for Pediatric Severe Traumatic Brain Injury – Frontiers in Pediatrics
Cohort Study | Incidence of antipsychotic use among community dwellers with and without Parkinson’s disease.
14 Sep, 2022 | 13:07h | UTCCommentaries:
Elevated Incidence of Antipsychotic Use Found Prior to Parkinson Disease Diagnosis – AJMC
Antipsychotics Use Climbs in Years Before Parkinson’s Diagnosis: Study – Parkinson’s News Today
Expert Opinion | Clinical management of pregnancy in women with polycystic ovary syndrome.
14 Sep, 2022 | 13:02h | UTC
M-A | The effectiveness of self-care interventions in chronic illness.
14 Sep, 2022 | 13:03h | UTC
Phase 2 RCT | Sequencing of Ipilimumab plus Nivolumab and Encorafenib plus Binimetinib for untreated BRAF-mutated metastatic melanoma.
14 Sep, 2022 | 13:01h | UTCSequencing of Ipilimumab Plus Nivolumab and Encorafenib Plus Binimetinib for Untreated BRAF-Mutated Metastatic Melanoma (SECOMBIT): A Randomized, Three-Arm, Open-Label Phase II Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Data from the phase II SECOMBIT trial of treatment sequencing for BRAF-mutant metastatic melanoma suggests that nivo+ipi followed by encorafenib + binimetinib results in better OS than the reverse sequence, although with a greater risk of grade 3-4 AEs: https://t.co/9jC2oMI4Az
— NatureRevClinOncol (@NatRevClinOncol) September 7, 2022
RCT | Efficacy and safety of carboplatin with nab-paclitaxel vs. docetaxel in older patients with squamous non-small-cell lung cancer.
14 Sep, 2022 | 13:00h | UTC
Commentary on Twitter
New research: in a ph3 RCT pts aged 70 yrs and older with squamous non-small-cell #lungcancer, overall survival was significantly longer with #carboplatin & nab-paclitaxel vs #docetaxel
👉https://t.co/qOuaVpO61f pic.twitter.com/TSnMguOkoR— The Lancet Healthy Longevity (@LancetLongevity) December 9, 2021
Cohort Study | Aerosol precautions and airway complications.
14 Sep, 2022 | 12:57h | UTC
Commentary on Twitter
🔐FFP2/3 mask use by anaesthetists was associated with increased patient airway complications👇@t_Potter_1 @john_n_cronin @justin_kua @EvieNurmi @dannyjnwong @dr_imranahmad @doctimcook @elboghdadly @PeriopResearch @STAResearch @SQuAResNet @NWRAG
🔗https://t.co/NnJZqGzU4R pic.twitter.com/PhSsU0KcGC
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) September 8, 2022