Daily Archives: August 3, 2022
Guideline | Preventing obesity in midlife women.
3 Aug, 2022 | 14:37h | UTCCommentary: Counseling Can Prevent Obesity in Normal, Overweight Women – HealthDay
Commentary on Twitter
New guidelines aim to prevent #obesity in midlife women. @TheWPSI recommends counseling to prevent weight gain in all women at normal or overweight BMI. Full text available at https://t.co/P8VwBWIHXe @CedarsSinai @acog pic.twitter.com/YxTQVgXj59
— Annals of Int Med (@AnnalsofIM) August 2, 2022
M-A | Response to acute monotherapy for major depressive disorder in randomized, placebo controlled trials.
3 Aug, 2022 | 14:31h | UTC
RECOVERY Trial | Baricitinib in patients admitted to hospital with COVID-19.
3 Aug, 2022 | 14:34h | UTCInvited Commentary: Baricitinib in COVID-19: a coming-of-age from artificial intelligence to reducing mortality – The Lancet
Related:
WHO recommends two new drugs to treat COVID-19 – World Health Organization
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 – New England Journal of Medicine
Commentary on Twitter
New @TheLancet
The largest trial of baricitinib, a JAK-inhibitor drug repurposed via #AI data mining, reduced Covid mortality and the overall reduction consistent with 8 previous RCTs (~20%)https://t.co/5fHDBBvm3Q pic.twitter.com/GDFzcU26H6— Eric Topol (@EricTopol) July 29, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
Antivirals with activity against Monkeypox: a clinically oriented review.
3 Aug, 2022 | 14:26h | UTCRelated:
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Review | Diagnosis, treatment, and prevention of Malaria in the US.
3 Aug, 2022 | 14:27h | UTCDiagnosis, Treatment, and Prevention of Malaria in the US: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis, Treatment, and Prevention of Malaria in the US – JAMA
Cohort Study | Association between gout flare and subsequent cardiovascular events among patients with gout.
3 Aug, 2022 | 14:30h | UTCAssociation Between Gout Flare and Subsequent Cardiovascular Events Among Patients With Gout – JAMA (free for a limited period)
Editorial: Cardiovascular Events and Gout Flares – JAMA (free for a limited period)
News Release: Flare-ups of gout are linked to heart attack and stroke – University of Nottingham
Commentary: Association Between Gout Flare and Subsequent Cardiovascular Events – American College of Cardiology
Cohort Study | Association of higher-dose fluoroquinolone therapy with serious adverse events in older adults with advanced chronic kidney disease.
3 Aug, 2022 | 14:22h | UTC
Evidence Synthesis | Deprescribing medicines in older people living with multimorbidity and polypharmacy.
3 Aug, 2022 | 14:20h | UTCRelated:
Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports
Deprescribing in Palliative Cancer Care – Life
Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360
Polypharmacy Management in Older Patients – Mayo Clinic Proceedings
Eliminating Medication Overload: A National Action Plan – Lown Institute
Common ED Medication Errors: Polypharmacy – emDocs
Current and future perspectives on the management of polypharmacy – BMC Family Practice
Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international
Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety
Designing Infographics | Visual representations for enhancing education, communication, and scientific research.
3 Aug, 2022 | 14:24h | UTCRelated:
As scientists take to Twitter, study shows power of ‘visual abstract’ graphics – Scienmag
See also: an open-source primer on visual abstracts
Deep learning electrocardiographic analysis for detection of left-sided valvular heart disease.
3 Aug, 2022 | 14:19h | UTC
Commentary from the author on Twitter (thread – click for more)
Out today in @JACCJournals, our ValveNet study shows a ML model can detect mod-severe left sided valve disease from ECG. This model is currently running live in our health system daily. Now let me tell you everything wrong with it! A brief ? https://t.co/rjtZxxTLt9 pic.twitter.com/oZKDDnZqYU
— Pierre Elias, MD (@PierreEliasMD) August 1, 2022
Guideline | Male lower urinary tract symptoms/benign prostatic hyperplasia.
3 Aug, 2022 | 14:17h | UTCRelated:
Podcast: LUTS, BPH, and Urinary Incontinence Triple Distilled – The Curbsiders
Guideline | Androgen deprivation therapy: adverse events and management strategies.
3 Aug, 2022 | 14:15h | UTC
RCT | Effect of graded sensorimotor retraining on pain intensity in patients with chronic low back pain.
3 Aug, 2022 | 14:08h | UTCEffect of Graded Sensorimotor Retraining on Pain Intensity in Patients With Chronic Low Back Pain: A Randomized Clinical Trial – JAMA (free for a limited period)
News release: An effective new treatment for chronic back pain targets the nervous system – University of New South Wales
Commentary on Twitter
A graded sensorimotor retraining intervention, compared with a sham procedure and attention control, resulted in a statistically significant improvement in pain intensity at 18 weeks. https://t.co/MXO89JeOSe pic.twitter.com/0A865RWW85
— JAMA (@JAMA_current) August 2, 2022
Consensus statements for pharmacological management, monitoring of therapies, and comorbidity management of psoriatic arthritis.
3 Aug, 2022 | 14:09h | UTC
RCT | Patiromer for the management of hyperkalemia in heart failure with reduced ejection fraction.
3 Aug, 2022 | 14:06h | UTC
Commentary on Twitter
No one wants to add meds just so you can add more meds. BUT, adding patiromer in select patients with HFrEF so you can optimize GDMT sure is compelling… ? https://t.co/79gSEwon4y
— ATRIUM Cardiology (@ATRIUMRx) July 29, 2022
M-A | Global prevalence of non-tuberculous mycobacteria in adults with non-cystic fibrosis bronchiectasis 2006–2021.
3 Aug, 2022 | 14:04h | UTC
Study shows the incidence of obesity among US children is increasing.
3 Aug, 2022 | 14:00h | UTCChanges in the Incidence of Childhood Obesity – Pediatrics
Original Study: Childhood Obesity Rate in the U.S. Higher Now Than 12 Years Prior – HealthDay
RCT | Sintilimab plus bevacizumab biosimilar IBI305 and chemotherapy for patients with EGFR-mutated non-squamous non-small-cell lung cancer who progressed on EGFR tyrosine-kinase inhibitor therapy.
3 Aug, 2022 | 14:02h | UTCSintilimab plus bevacizumab biosimilar IBI305 and chemotherapy for patients with EGFR-mutated non-squamous non-small-cell lung cancer who progressed on EGFR tyrosine-kinase inhibitor therapy (ORIENT-31): first interim results from a randomised, double-blind, multicentre, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Online first: #Sintilimab plus #bevacizumab #biosimilar IBI305 and chemotherapy for patients with EGFR-mutated non-squamous non-small-cell #lungcancer #NSCLC who progressed on EGFR TKI therapy: first interim results from ORIENT-31 https://t.co/5VwmLCcGW5 pic.twitter.com/RWeeyfuC6i
— The Lancet Oncology (@TheLancetOncol) August 2, 2022
Review | Management of alcohol-related liver disease and its complications.
3 Aug, 2022 | 13:56h | UTCManagement of Alcohol-Related Liver Disease and Its Complications – Clinical Drug Investigation
Related Guideline: Management of alcohol-related liver disease: the French Association for the Study of the Liver and the French Alcohol Society clinical guidelines – Liver International
Commentary on Twitter (thread – click for more)
Excellent review about the Management of Alcohol-Related Liver Disease and Its Complications carried out by Dr. Cabezas.https://t.co/VICukJ3jEt
Key points:
1. It is still a stigmatized condition with underlying pathology.@AEEHLiver @sepdigestiva #LiverTwitter …— Javier Crespo (@DrJavierCrespo) July 29, 2022
Cohort Study | Association between early left ventricular ejection fraction improvement after transcatheter aortic valve replacement and 5-year clinical outcomes.
3 Aug, 2022 | 13:58h | UTCAssociation Between Early Left Ventricular Ejection Fraction Improvement After Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes – JAMA Cardiology (link to abstract – $ for full-text)
Commentary: Early LV Recovery After TAVI Points to Better 5-Year Survival – TCTMD
Commentary on Twitter
In patients with severe #aorticstenosis and left ventricular ejection fraction (LVEF) less than 50%, 1 in 3 experience LVEF improvement within 1 month after TAVR. Early LVEF improvement is associated with lower 5-year all-cause and cardiac death. https://t.co/81H6roA8nV
— JAMA Cardiology (@JAMACardio) July 27, 2022
Trends in thoracic aortic aneurysm hospital admissions, interventions and mortality in England between 1998 to 2020: An observational study.
3 Aug, 2022 | 13:55h | UTC
Cohort Study | Incidence of acute chest syndrome in children with sickle cell disease following implementation of the 13-valent pneumococcal conjugate vaccine.
3 Aug, 2022 | 13:53h | UTC
Commentary on Twitter
#OrigInvestigation: Reduction of acute chest syndrome incidence in children with sickle-cell disease following 13-valent pneumococcal conjugate vaccine (PCV13) implementation in France. https://t.co/MuG6T0g5FU
— JAMA Network Open (@JAMANetworkOpen) August 2, 2022