Daily Archives: July 20, 2022
Open-label RCT | Moderate-intensity statin plus ezetimibe is noninferior to high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease.
20 Jul, 2022 | 12:32h | UTCLong-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
AHA Scientific Statement | Polygenic risk scores for cardiovascular disease.
20 Jul, 2022 | 12:31h | UTC
High-sensitivity cardiac troponin and the 2021 AHA/ACC Guidelines for the evaluation and diagnosis of acute chest pain.
20 Jul, 2022 | 12:29h | UTCHigh-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain – Circulation (free for a limited period)
Commentary on Twitter
#Primer HS Cardiac Troponin & Guidelines for Evaluation and Diagnosis of Acute Check Pain #AHAJournals https://t.co/avcm6LEbgb pic.twitter.com/zs8yRe6u1y
— Circulation (@CircAHA) July 13, 2022
Guideline | Neurological manifestations of post-COVID-19 syndrome.
20 Jul, 2022 | 12:18h | UTC
Top 20 research studies of 2021 for primary care physicians.
20 Jul, 2022 | 12:24h | UTCTop 20 Research Studies of 2021 for Primary Care Physicians – American Family Physician (PDF)
Related: Top studies of 2021 relevant to primary care: From the PEER team – Canadian Family Physician
A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics.
20 Jul, 2022 | 12:27h | UTC
A primer on Monkeypox virus for obstetrician-gynecologists: diagnosis, prevention, and treatment.
20 Jul, 2022 | 12:22h | UTCRelated:
With monkeypox spreading globally, many experts believe the virus can’t be contained – STAT
Diagnosis, Prevention, and Treatment of Monkeypox – JAMA
7 of your most pressing monkeypox vaccine questions, answered – Vox
How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic
Prevention and Treatment of Monkeypox – Drugs
Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP
No room for complacency – World Health Organization
Multi-country monkeypox outbreak: situation update – World Health Organization
Monkeypox Genital Lesions – New England Journal of Medicine
Monkeypox vaccination begins — can the global outbreaks be contained? – Nature
Incubation period for monkeypox: Estimates from the Netherlands.
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
Rename monkeypox strains to remove geographic stigma, researchers say – Science
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
M-A | Colchicine does not improve outcomes in patients with COVID-19.
20 Jul, 2022 | 12:20h | UTC
AAP Policy Statement | Vision and concussion: symptoms, signs, evaluation, and treatment.
20 Jul, 2022 | 12:14h | UTCVision and Concussion: Symptoms, Signs, Evaluation, and Treatment – Pediatrics
Commentary: Guidance Issued for Managing Visual Disorders After Pediatric Concussion – HealthDay
Guidelines on the diagnosis and treatment of prostate cancer.
20 Jul, 2022 | 12:11h | UTCThe Swedish national guidelines on prostate cancer – Scandinavian Journal of Urology
Part 2: Recurrent, metastatic and castration resistant disease
A guide to regional analgesia for total knee arthroplasty.
20 Jul, 2022 | 12:13h | UTCA guide to regional analgesia for Total Knee Arthroplasty – Efort Open Reviews
M-A | Costs of multimorbidity.
20 Jul, 2022 | 12:06h | UTCCosts of multimorbidity: a systematic review and meta-analyses – BMC Medicine
Related:
Systematic review of high-cost patients’ characteristics and healthcare utilization – BMJ Open
Multimorbidity: a priority for global health research – The Academy of Medical Sciences
The global burden of multiple chronic conditions: A narrative review – Preventive Medicine Reports
Redesigning Care for High-Cost, High-Risk Patients – Harvard Business Review
Multimorbidity: clinical assessment and management – NICE Guideline
Richard Smith: The challenge of high need, high cost patients – The BMJ Blogs
Better Care for People with Complex Needs – Institute for Healthcare Improvement
The epidemiological landscape of multiple myeloma: a global cancer registry estimate of disease burden, risk factors, and temporal trends.
20 Jul, 2022 | 12:08h | UTCThe epidemiological landscape of multiple myeloma: a global cancer registry estimate of disease burden, risk factors, and temporal trends – The Lancet Haematology (free registration required)
Commentary on Twitter (thread – click for more)
@CUHKMedicine: collaborative work with @APRU1997 colleagues published. @TheLancet Haematology: Epidemiological Landscape of Multiple Myeloma from Cancer Registry Analysis @CUHKGlobal pic.twitter.com/17tr2Z30Xh
— Wong Chi Sang Martin (@drwong_martin) July 14, 2022
Updates on enhanced recovery after surgery for radical cystectomy.
20 Jul, 2022 | 12:03h | UTCUpdates on enhanced recovery after surgery for radical cystectomy – Therapeutic Advances in Urology
Related:
Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines
Cohort Study | Clinical and pathological predictors of relapse in IgG4-related disease.
20 Jul, 2022 | 12:01h | UTC
Review | Contrast-associated acute kidney injury.
20 Jul, 2022 | 12:00h | UTCContrast-Associated Acute Kidney Injury – Journal of Clinical Medicine
M-A | Associations of multidomain interventions with improvements in cognition in mild cognitive impairment.
20 Jul, 2022 | 11:57h | UTC
Commentary on Twitter
In this meta-analysis of 28 studies, multidomain interventions such as combined cognitive + physical training improved cognitive outcomes in older adults with mild cognitive impairment vs cognitive or physical training alone. https://t.co/7cI9gbyTrj
— JAMA Network Open (@JAMANetworkOpen) May 3, 2022
Review | “No-Reflow” phenomenon.
20 Jul, 2022 | 11:58h | UTC“No-Reflow” Phenomenon: A Contemporary Review – Journal of Clinical Medicine
RCT | Therapist-guided internet-based psychodynamic therapy vs. cognitive behavioral therapy for adolescent depression.
20 Jul, 2022 | 11:54h | UTC
Commentary on Twitter
NEW Research: "Therapist-guided internet-based #psychodynamic therapy versus #cognitivebehaviouraltherapy for adolescent #depression in Sweden: a randomised, clinical, non-inferiority trial". @Stockholm_Unihttps://t.co/wZ15f80VSg pic.twitter.com/B78TJlrDVL
— The Lancet Digital Health (@LancetDigitalH) July 6, 2022
Retrospective Cohort Study | The impact of frailty on short-term mortality following primary total hip and knee arthroplasty due to osteoarthritis.
20 Jul, 2022 | 11:50h | UTC
Systematic Review | Impact of early postoperative indwelling urinary catheter removal.
20 Jul, 2022 | 11:48h | UTC
Review | Opioid sparing strategies for perioperative pain management other than regional anesthesia.
20 Jul, 2022 | 11:47h | UTC
Review | New antibiotics for hospital-acquired pneumonia and ventilator-associated pneumonia.
20 Jul, 2022 | 11:44h | UTC
M-A | Efficacy and tolerability of cranial electrotherapy stimulation in the treatment of anxiety.
20 Jul, 2022 | 11:42h | UTC
Commentary on Twitter
MA: cranial electrotherapy stimulation, a portable device, reduced anxiety symptoms vs. control group [g= −0.625; −0.952 to −0.298]. CES reduced both primary and secondary anxiety (g= −1.218 and −0.334, respectively). No severe AEs were reported https://t.co/Z9f9vnvmVD pic.twitter.com/wyN91oz7Mi
— PfOL (@psychopharmacol) June 15, 2022
Phase 1b/2 RCT | Niraparib plus nivolumab vs. niraparib plus ipilimumab in patients with platinum-sensitive advanced pancreatic cancer.
20 Jul, 2022 | 11:39h | UTCNiraparib plus nivolumab or niraparib plus ipilimumab in patients with platinum-sensitive advanced pancreatic cancer: a randomised, phase 1b/2 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Online first: #Niraparib plus #nivolumab or niraparib plus #ipilimumab in patients with platinum-sensitive advanced #pancreaticcancer: a randomised, phase 1b/2 trial https://t.co/HBci82F8zp pic.twitter.com/E8Qo2Antzt
— The Lancet Oncology (@TheLancetOncol) July 8, 2022