Daily Archives: July 14, 2022
Pressure ulcers (pressure injuries) | Cochrane Library evidence and resources.
14 Jul, 2022 | 13:03h | UTCPressure ulcers (pressure injuries): evidence and resources – Evidently Cochrane
RCT | Pharmacogenomic testing for drug-gene interactions provides little benefit for the remission of symptoms in major depressive disorder.
14 Jul, 2022 | 13:05h | UTCEffect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Pharmacogenomic Testing for Next-Step Antidepressant Selection: Still a Work in Progress – JAMA (free for a limited period)
Commentary: Does Pharmacogenomic Testing Improve Outcomes in Major Depressive Disorder? — The evidence is unclear – MedPage Today (free registration required)
Commentary on Twitter
In this randomized clinical trial, pharmacogenomic testing for drug-gene interactions in major depressive disorder reduced prescription of medications with predicted drug-gene interactions but had small and nonpersistent effects on symptom remission. https://t.co/Z2OIK3h1Bo pic.twitter.com/8eKSipfBFN
— JAMA (@JAMA_current) July 12, 2022
FDA authorizes emergency use of Novavax COVID-19 vaccine.
14 Jul, 2022 | 13:01h | UTCCommentaries:
FDA authorizes Novavax Covid vaccine, in hopes the traditional shot will convince holdouts – STAT
US regulators OK new COVID-19 shot option from Novavax – Associated Press
How to bounce back from a PhD-project failure.
14 Jul, 2022 | 12:59h | UTCHow to bounce back from a PhD-project failure – Nature
WHO Updated Report | Severe acute hepatitis of unknown etiology in children.
14 Jul, 2022 | 12:54h | UTCSevere acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Related:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
A case series of children with acute hepatitis and human Adenovirus infection.
14 Jul, 2022 | 12:56h | UTCA Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Related Study: Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 — Two studies point to a suspiciously high prevalence – MedPage Today (free registration required)
Commentaries on Twitter
A majority of children admitted to a single hospital in late 2021–early 2022 with acute hepatitis of unknown cause tested positive for adenovirus. This report describes the children’s illnesses and outcomes. https://t.co/QYvi6U1jUN pic.twitter.com/auPRq1duQm
— NEJM (@NEJM) July 13, 2022
From January–April 2022, 44 children with acute hepatitis of unknown cause were referred to a liver-transplantation center in the U.K. Six underwent liver transplantation. https://t.co/CMI4KCqdxM pic.twitter.com/og72u58L5R
— NEJM (@NEJM) July 13, 2022
Nationwide cohort study | Safety of heterologous primary and booster schedules with ChAdOx1-S and BNT162b2 or mRNA-1273 vaccines.
14 Jul, 2022 | 12:52h | UTC
M-A of RCTs | Megestrol Acetate not beneficial for cancer-related anorexia/cachexia.
14 Jul, 2022 | 12:50h | UTC
Coronary Artery Disease Reporting and Data System (CAD-RADS 2.0) reporting system for patients undergoing coronary CT angiography.
14 Jul, 2022 | 12:49h | UTCCommentary: SCCT Releases New Expert Consensus Document on CAD Reporting – American College of Cardiology
Consensus Statement | Informed consent for suspension microlaryngoscopy.
14 Jul, 2022 | 12:44h | UTC
Consensus Statement | Clinical indications and triaging for adult transthoracic echocardiography.
14 Jul, 2022 | 12:47h | UTC
The EBMT nursing guidelines on CAR-T Therapy | A framework for patient care and managing common toxicities.
14 Jul, 2022 | 12:45h | UTC
Systematic Review | Anti‐IL‐5 therapies for asthma.
14 Jul, 2022 | 12:40h | UTCAnti‐IL‐5 therapies for asthma – Cochrane Library
RCT | Erythropoietin not beneficial for hypoxic-ischemic encephalopathy in newborns.
14 Jul, 2022 | 12:42h | UTCTrial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns – New England Journal of Medicine (link to abstract – $ for full-text)
Review | Cardiovascular disease in myeloproliferative neoplasms.
14 Jul, 2022 | 12:38h | UTC
How to treat renal cell carcinoma: the current treatment landscape and cardiovascular toxicities.
14 Jul, 2022 | 12:35h | UTC
Cohort Study | Prediction models for celiac disease development in children from high-risk families.
14 Jul, 2022 | 12:31h | UTC
Randomized crossover trial | AI reduces miss rate of precancerous polyps in colorectal cancer screening.
14 Jul, 2022 | 12:29h | UTCNews Release: AI reduces miss rate of precancerous polyps in colorectal cancer screening – Mayo Clinic
Original Study: Impact of Artificial Intelligence on Miss Rate of Colorectal Neoplasia – Gastroenterology
Prevalence of cardiovascular disease in patients with potentially curable malignancies: a national registry dataset analysis.
14 Jul, 2022 | 12:33h | UTC
RCT | Effects of the short stitch technique for midline abdominal closure on incisional hernia.
14 Jul, 2022 | 12:27h | UTC
Review | Anesthesia for tracheal resection and anastomosis.
14 Jul, 2022 | 12:25h | UTC
Review | Neonatal acute kidney injury.
14 Jul, 2022 | 12:21h | UTCNeonatal Acute Kidney Injury – Frontiers in Pediatrics
RCT | Effect of ultrasonography-guided corticosteroid injection vs. placebo added to exercise therapy for Achilles tendinopathy.
14 Jul, 2022 | 12:18h | UTCCommentary: Trial Backs Steroid Shots for Stubborn Achilles Tendon Pain — Corticosteroid bests placebo when combined with resistance exercise therapy – MedPage Today (free registration required)
Commentary on Twitter
In this RCT, corticosteroid injections + exercise therapy was more effective for patients with long-standing Achilles tendinopathy compared to placebo injections + exercise therapy. https://t.co/nkTH0OYL4a
— JAMA Network Open (@JAMANetworkOpen) July 11, 2022
Review | Temporary mechanical circulatory support: devices, outcomes, and future directions.
14 Jul, 2022 | 12:23h | UTC
The Global Retinoblastoma Outcome Study | A prospective, cluster-based analysis of 4,064 patients from 149 countries.
14 Jul, 2022 | 12:16h | UTCInvited Commentary: Retinoblastoma as a lens for correctable disparities worldwide – The Lancet Global Health