Daily Archives: July 13, 2022
RCT | Endovascular thrombectomy NOT noninferior to standard bridging thrombolytic with endovascular thrombectomy within 4.5 h of stroke onset.
13 Jul, 2022 | 11:57h | UTCEndovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Related Study: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
RCT | Thrombectomy alone NOT noninferior to intravenous alteplase plus thrombectomy in patients with stroke.
13 Jul, 2022 | 11:55h | UTCThrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Related Study: Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
RCT | Myosin inhibition in patients with obstructive hypertrophic cardiomyopathy referred for septal reduction therapy.
13 Jul, 2022 | 11:52h | UTC
Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses.
13 Jul, 2022 | 11:51h | UTC
Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis.
13 Jul, 2022 | 11:49h | UTC
M-A | Home oxygen for moderate hypoxemia in chronic obstructive pulmonary disease.
13 Jul, 2022 | 11:47h | UTCHome oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Home oxygen probably makes little or no difference to 3-year mortality in pts with #COPD and moderate hypoxaemia
Systematic review & meta-analysis from Yves Lacasse & colleagues https://t.co/8wDrkEd1LH pic.twitter.com/UoOqW7hngT
— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022
RCT | Neutropenic versus regular diet for acute leukemia induction chemotherapy.
13 Jul, 2022 | 11:45h | UTCNeutropenic versus regular diet for acute leukaemia induction chemotherapy: randomised controlled trial – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Related:
Association between the dietary regimen and infection-related complications in neutropenic high-risk patients with cancer – European Journal of Cancer (link to abstract – $ for full-text)
Neutropenic diets to prevent cancer infections: updated systematic review and meta-analysis – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Things We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (PDF)
Cohort Study | Risk and timing of noncardiac surgery after transcatheter aortic valve implantation.
13 Jul, 2022 | 11:43h | UTCCommentaries:
Surgery After TAVR: Waiting a Month or More Not Really Better— Prosthesis-patient mismatch, paravalvular regurgitation the bigger issues for surgical candidates – MedPage Today (free registration required)
Commentaries on Twitter
https://twitter.com/JAMANetworkOpen/status/1545120466326749186
https://twitter.com/preopconsult/status/1546167570771894272
ESC Consensus Statement | Digital health in older adults for the prevention and management of cardiovascular diseases and frailty.
13 Jul, 2022 | 11:42h | UTC
AHA Science Advisory | Elucidating the clinical implications and pathophysiology of pulmonary hypertension in heart failure with preserved ejection fraction: a call to action.
13 Jul, 2022 | 11:40h | UTC
ESMO recommendations on the use of circulating tumor DNA assays for patients with cancer.
13 Jul, 2022 | 11:38h | UTC
Nutrition and lifestyle recommendations for patients with gout and hyperuricemia.
13 Jul, 2022 | 11:37h | UTC
Podcast | Multiple sclerosis pearls for the primary care physician.
13 Jul, 2022 | 11:33h | UTC#344 Multiple Sclerosis with Dr. Annette Okai – The Curbsiders
What cardiologists should know about sleep.
13 Jul, 2022 | 11:32h | UTCWhat cardiologists should know about sleep – European Heart Journal (free for a limited period)
M-A | Risk factors of delirium in pediatric intensive care units.
13 Jul, 2022 | 11:35h | UTCRisk factors of delirium in paediatric intensive care units: A meta-analysis – PLOS One
RCT | Effects of cuisine-based Chinese heart-healthy diet in lowering blood pressure among adults in China.
13 Jul, 2022 | 11:29h | UTCNews Release: Heart-healthy, lower sodium version of traditional Chinese cuisine lowered blood pressure – American Heart Association
Commentary: Modified Chinese Food Diet Lowers BP in Hypertensive Adults – HealthDay
M-A | The effect of fiber supplementation on chronic constipation in adults.
13 Jul, 2022 | 11:30h | UTC
Report | The first 5 years of uterus transplant in the US.
13 Jul, 2022 | 11:27h | UTCThe First 5 Years of Uterus Transplant in the US: A Report From the United States Uterus Transplant Consortium – JAMA Surgery (link to abstract – $ for full-text)
Commentary: Good Outcomes From First 5 Years of Uterus Transplants, But Concerns Remain – U.S.News
Commentary on Twitter
A multi-center study found uterus transplantation in the United States to be a safe, effective therapy for women with uterine-factor infertility to have children. https://t.co/nNYgjdP0fA
— JAMA Surgery (@JAMASurgery) July 6, 2022
Genetic testing in prostate cancer management: considerations informing primary care.
13 Jul, 2022 | 11:25h | UTC
Female erectile tissues and sexual dysfunction after pelvic radiotherapy: a scoping review.
13 Jul, 2022 | 11:23h | UTC
Network M-A | Treatment of idiopathic membranous nephropathy for moderate or severe proteinuria.
13 Jul, 2022 | 11:16h | UTCRelated Cochrane Review:
Summary: Immunosuppressive treatment for adults with idiopathic membranous nephropathy – Cochrane Library
Original Study: Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome – Cochrane Library
Modern developments in germline pharmacogenomics for oncology prescribing.
13 Jul, 2022 | 11:21h | UTC
M-A | Oral iron supplementation in patients with heart failure.
13 Jul, 2022 | 11:17h | UTC
M-A | Dual-hormone artificial pancreas for glucose control in type 1 diabetes.
13 Jul, 2022 | 11:19h | UTC
M-A | Utility of provocative testing in the diagnosis and genotyping of congenital long QT syndrome.
13 Jul, 2022 | 11:13h | UTC