Daily Archives: July 13, 2022
RCT | Endovascular thrombectomy NOT noninferior to standard bridging thrombolytic with endovascular thrombectomy within 4.5 h of stroke onset.
13 Jul, 2022 | 11:57h | UTCEndovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Related Study: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
RCT | Thrombectomy alone NOT noninferior to intravenous alteplase plus thrombectomy in patients with stroke.
13 Jul, 2022 | 11:55h | UTCThrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Related Study: Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
RCT | Myosin inhibition in patients with obstructive hypertrophic cardiomyopathy referred for septal reduction therapy.
13 Jul, 2022 | 11:52h | UTC
Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses.
13 Jul, 2022 | 11:51h | UTC
Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis.
13 Jul, 2022 | 11:49h | UTC
M-A | Home oxygen for moderate hypoxemia in chronic obstructive pulmonary disease.
13 Jul, 2022 | 11:47h | UTCHome oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Home oxygen probably makes little or no difference to 3-year mortality in pts with #COPD and moderate hypoxaemia
Systematic review & meta-analysis from Yves Lacasse & colleagues https://t.co/8wDrkEd1LH pic.twitter.com/UoOqW7hngT
— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022
RCT | Neutropenic versus regular diet for acute leukemia induction chemotherapy.
13 Jul, 2022 | 11:45h | UTCNeutropenic versus regular diet for acute leukaemia induction chemotherapy: randomised controlled trial – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Related:
Association between the dietary regimen and infection-related complications in neutropenic high-risk patients with cancer – European Journal of Cancer (link to abstract – $ for full-text)
Neutropenic diets to prevent cancer infections: updated systematic review and meta-analysis – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Things We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (PDF)
Cohort Study | Risk and timing of noncardiac surgery after transcatheter aortic valve implantation.
13 Jul, 2022 | 11:43h | UTCCommentaries:
Surgery After TAVR: Waiting a Month or More Not Really Better— Prosthesis-patient mismatch, paravalvular regurgitation the bigger issues for surgical candidates – MedPage Today (free registration required)
Commentaries on Twitter
In this cohort study, noncardiac surgery (NS) after transcatheter aortic valve implantation (TAVI) was not associated with more perioperative adverse events. Suboptimal device performance was associated with increased risk of adverse outcomes after NS. https://t.co/OYSLECeOzt
— JAMA Network Open (@JAMANetworkOpen) July 7, 2022
Interesting analysis of 300 pts undergoing NCS after TAVI: NCS may be performed early (<30d) after successful TAVI. Suboptimal device performance (prosthesis-pt mismatch, paravalvular regurg) was associated with incr risk
Risk and Timing of NCS After TAVI https://t.co/ILS3YBFcyz— Steven Cohn, MD (@preopconsult) July 10, 2022
ESC Consensus Statement | Digital health in older adults for the prevention and management of cardiovascular diseases and frailty.
13 Jul, 2022 | 11:42h | UTC
AHA Science Advisory | Elucidating the clinical implications and pathophysiology of pulmonary hypertension in heart failure with preserved ejection fraction: a call to action.
13 Jul, 2022 | 11:40h | UTC
ESMO recommendations on the use of circulating tumor DNA assays for patients with cancer.
13 Jul, 2022 | 11:38h | UTC
Nutrition and lifestyle recommendations for patients with gout and hyperuricemia.
13 Jul, 2022 | 11:37h | UTC
Podcast | Multiple sclerosis pearls for the primary care physician.
13 Jul, 2022 | 11:33h | UTC#344 Multiple Sclerosis with Dr. Annette Okai – The Curbsiders
What cardiologists should know about sleep.
13 Jul, 2022 | 11:32h | UTCWhat cardiologists should know about sleep – European Heart Journal (free for a limited period)
M-A | Risk factors of delirium in pediatric intensive care units.
13 Jul, 2022 | 11:35h | UTCRisk factors of delirium in paediatric intensive care units: A meta-analysis – PLOS One
RCT | Effects of cuisine-based Chinese heart-healthy diet in lowering blood pressure among adults in China.
13 Jul, 2022 | 11:29h | UTCNews Release: Heart-healthy, lower sodium version of traditional Chinese cuisine lowered blood pressure – American Heart Association
Commentary: Modified Chinese Food Diet Lowers BP in Hypertensive Adults – HealthDay
M-A | The effect of fiber supplementation on chronic constipation in adults.
13 Jul, 2022 | 11:30h | UTC
Report | The first 5 years of uterus transplant in the US.
13 Jul, 2022 | 11:27h | UTCThe First 5 Years of Uterus Transplant in the US: A Report From the United States Uterus Transplant Consortium – JAMA Surgery (link to abstract – $ for full-text)
Commentary: Good Outcomes From First 5 Years of Uterus Transplants, But Concerns Remain – U.S.News
Commentary on Twitter
A multi-center study found uterus transplantation in the United States to be a safe, effective therapy for women with uterine-factor infertility to have children. https://t.co/nNYgjdP0fA
— JAMA Surgery (@JAMASurgery) July 6, 2022
Genetic testing in prostate cancer management: considerations informing primary care.
13 Jul, 2022 | 11:25h | UTC
Female erectile tissues and sexual dysfunction after pelvic radiotherapy: a scoping review.
13 Jul, 2022 | 11:23h | UTC
Network M-A | Treatment of idiopathic membranous nephropathy for moderate or severe proteinuria.
13 Jul, 2022 | 11:16h | UTCRelated Cochrane Review:
Summary: Immunosuppressive treatment for adults with idiopathic membranous nephropathy – Cochrane Library
Original Study: Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome – Cochrane Library
Modern developments in germline pharmacogenomics for oncology prescribing.
13 Jul, 2022 | 11:21h | UTC
M-A | Oral iron supplementation in patients with heart failure.
13 Jul, 2022 | 11:17h | UTC
M-A | Dual-hormone artificial pancreas for glucose control in type 1 diabetes.
13 Jul, 2022 | 11:19h | UTC
M-A | Utility of provocative testing in the diagnosis and genotyping of congenital long QT syndrome.
13 Jul, 2022 | 11:13h | UTC