Daily Archives: June 23, 2022
AHA Scientific Statement: Cardiopulmonary consequences of vaping in adolescents.
23 Jun, 2022 | 13:03h | UTCNews Release: Action needed to reduce e-cigarette use among adolescents to lower lifetime CVD risk – American Heart Association
Sleep-Related Infant Deaths: Updated AAP 2022 recommendations for reducing infant deaths in the sleep environment.
23 Jun, 2022 | 13:05h | UTCCommentaries:
New safe-sleep guidelines aim to reduce infant deaths – University of Virginia Health System
AAP Updates Recommendations for Safe Infant Sleep Practices – HealthDay
Commentary on Twitter
Each year in the US approximately 3,500 infants die from sleep-related infant deaths. The @AmerAcadPeds recommends a safe sleep environment to reduce the risk of all sleep-related deaths. This Policy Statement provides updated guidance: https://t.co/y3RxNffsEv #Pediatrics pic.twitter.com/WFCKPJFdPd
— AAP Pediatrics (@aap_peds) June 22, 2022
RCT: Effect of MRI-guided fibrosis ablation vs. conventional catheter ablation on atrial arrhythmia recurrence in patients with persistent atrial fibrillation.
23 Jun, 2022 | 12:57h | UTCEffect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The DECAAF II Randomized Clinical Trial – JAMA (free for a limited period)
News Release: Global AFib study finds simple approach is best for ablation procedures – Tulane University
Commentary on Twitter
Randomized clinical trial of patients with persistent #atrialfibrillation found no significant difference in atrial arrhythmia recurrence in the MRI-guided fibrosis ablation group compared with the pulmonary vein isolation only group. https://t.co/mCyNR4rpTH
— JAMA (@JAMA_current) June 21, 2022
RCT: Effectiveness and safety of early initiation of poststernotomy cardiac rehabilitation exercise training.
23 Jun, 2022 | 12:59h | UTCEffectiveness and Safety of Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training: The SCAR Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary on Twitter
RCT found starting exercise 2 weeks post-sternotomy was as effective as starting at 6 weeks. Clinicians and cardiac rehabilitation professionals can recommend starting exercise training as early as 2 weeks post-sternotomy. https://t.co/MpBhRmyfUh
— JAMA Cardiology (@JAMACardio) June 22, 2022
Ivermectin for COVID-19 Cochrane review update: 11 trials and no evidence of benefit shown.
23 Jun, 2022 | 10:38h | UTCNews Release: Ivermectin for COVID-19 review update: 11 trials and no evidence of benefit shown – Liverpool School of Tropical Medicine
Original Article: Ivermectin for preventing and treating COVID‐19 – Cochrane Library
Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library
We don’t know whether most medical treatments work, and we know even less about whether they cause harm – new study.
23 Jun, 2022 | 10:32h | UTCOriginal Study: Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis – Journal of Clinical Epidemiology (link to abstract – $ for full-text)
Commentary on Twitter
Of 1567 interventions tested in Cochrane reviews, only 5.6% had high quality evidence on first-listed primary outcomes and positive, statistically significant results. Harms were measured only for 36.8% of the interventions. https://t.co/Zl2GlZhiQZ
— Raffaele Rasoini (@RasoiniR) April 29, 2022
Systematic Review: SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19.
23 Jun, 2022 | 10:37h | UTCSARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19 – Cochrane Library
Risk factors for SARS-CoV-2 related severe Multisystem Inflammatory Syndrome in Children investigated in a Swedish population-based study.
23 Jun, 2022 | 10:36h | UTC
M-A: Incidence and etiology of infant Gram-negative bacteremia and meningitis in children.
23 Jun, 2022 | 10:27h | UTC
RCTs: Once daily oral relugolix combination therapy vs. placebo in patients with endometriosis-associated pain.
23 Jun, 2022 | 10:30h | UTCCommentaries:
Relugolix combination therapy for endometriosis pain – The Lancet (free registration required)
Commentary on Twitter
Treatment options for #endometriosis-associated pain are suboptimal.
Two new studies indicate once-daily relugolix combination therapy significantly improved pain and was well tolerated. 1/2 https://t.co/LBFgTMZSO2
— The Lancet (@TheLancet) June 21, 2022
Consensus report on anatomy, pathophysiology and clinical significance of the gastro-esophageal junction.
23 Jun, 2022 | 10:26h | UTC
Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk.
23 Jun, 2022 | 10:22h | UTC
AGA Guidelines on the pharmacological management of irritable bowel syndrome.
23 Jun, 2022 | 10:24h | UTCPart 1: Patients with diarrhea: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea – Gastroenterology
Part 2: Patients with constipation: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Constipation – Gastroenterology
Commentary: AGA issues guidance on drug treatment for patients with IBS – ACP Gastroenterology
Commentary on Twitter
Clinical decision support tool from the @AmerGastroAssn for #IBS based on the most recent evidence.
?IBS-C: https://t.co/OeswowXhIP
?IBS-D: https://t.co/4W8PbpV4b0
?Spotlight on IBS treatment: https://t.co/oxZfD3m8u5#MedTwitter #GITwitter #DGBI #FGID #motility pic.twitter.com/eiMqCdS8js
— John Damianos, M.D. (@john_damianosMD) June 22, 2022
International consensus statements on pre-invasive vulvar lesions.
23 Jun, 2022 | 10:21h | UTCNews Release: New Guidelines Address Treatment of Pre-Invasive Lesions of the Vulva – Wolters Kluwer Health: Lippincott
A Delphi study of rescue and clinical subject matter experts on the extrication of patients following a motor vehicle collision.
23 Jun, 2022 | 10:19h | UTC
RCT: Weaning of maintenance immunosuppressive therapy in lupus nephritis.
23 Jun, 2022 | 10:18h | UTC
Many researchers say they’ll share data — but don’t.
23 Jun, 2022 | 10:13h | UTCMany researchers say they’ll share data — but don’t – Nature
M-A: Intravenous iron vs. oral iron vs. no iron with or without erythropoiesis‐ stimulating agents for cancer patients with anemia.
23 Jun, 2022 | 10:10h | UTC
RCT: Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y Gastric bypass on weight loss, comorbidities, and reflux at 10 years in adult patients with obesity.
23 Jun, 2022 | 10:17h | UTCEffect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss, Comorbidities, and Reflux at 10 Years in Adult Patients With Obesity: The SLEEVEPASS Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentary on Twitter
10-year follow-up of the SLEEVEPASS RCT: both sleeve and gastric bypass resulted in good #weightloss. Reflux was more prevalent after sleeve. The incidence of #Barrettesophagus was much lower than in previous trials, and similar after both procedures. https://t.co/zRLzB6Nf7a
— JAMA Surgery (@JAMASurgery) June 22, 2022
Systematic Review: Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection.
23 Jun, 2022 | 10:09h | UTC
Commentary from the author on Twitter
Our Cochrane review assessed the impact of WASH interventions on soil-transmitted helminths and found a 29% reduction in odds (95%CI 0.54 to 0.94). OR:0.86 amongst RCTs (95%CI 0.74 to 1.01). So. Many Meta-regressions! Moderate effect, yet important! https://t.co/t7s7kTYurx
— Matthew Freeman (@MatthewCFreeman) June 21, 2022
M-A: Early versus delayed complete revascularization in patients presenting with ST-segment elevation myocardial infarction and multivessel disease.
23 Jun, 2022 | 10:11h | UTC
M-A: Effectiveness of pharmacological-based interventions, including education and prescribing strategies, to reduce subacute pain after total hip or knee arthroplasty.
23 Jun, 2022 | 10:04h | UTC
Commentary on Twitter
A systematic review of RCTs looking at effectiveness of pharmacological interventions to ⬇️ pain following total hip/knee arthroplasty. Interventions involving multimodal non-opioid analgesia & education show positive effects on ⬇️ pain intensity. https://t.co/t2majwzHPz pic.twitter.com/HoybWv2VFO
— Pain Medicine Journal (@PainMedJournal) March 31, 2022
RCTs: Risankizumab as induction therapy for Crohn’s disease.
23 Jun, 2022 | 10:02h | UTCRisankizumab as induction therapy for Crohn’s disease: results from the phase 3 ADVANCE and MOTIVATE induction trials – The Lancet (link to abstract – $ for full-text)
Related: Risankizumab as maintenance therapy for moderately to severely active Crohn’s disease: results from the multicentre, randomised, double-blind, placebo-controlled, withdrawal phase 3 FORTIFY maintenance trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
In patients with moderately to severely active Crohn's disease, risankizumab was effective and well tolerated as induction therapy, studies indicate.
Find out more: https://t.co/zg70L8RYka #crohnsdisease pic.twitter.com/9evGJAH8ke
— The Lancet (@TheLancet) June 1, 2022
Systematic Review: Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria.
23 Jun, 2022 | 10:07h | UTCPyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library
Summary: Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library
Cohort Study: Optimizing both disease control and glucocorticoid dosing is essential for bone protection in patients with rheumatic disease.
23 Jun, 2022 | 10:01h | UTCOptimising both disease control and glucocorticoid dosing is essential for bone protection in patients with rheumatic disease – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary: Low-dose glucocorticoids show no negative impact on BMD – medwire News
Commentary on Twitter
New and important study on #glucocorticoids and bone health in inflammatory rheumatic diseases. https://t.co/6XakxJO37y doses <5 mg/d together with low disease activity seem to have a low risk for #osteoporosis pic.twitter.com/Na5eMHLMS3
— ARD & RMD Open (@ARD_BMJ) June 12, 2022