Daily Archives: May 6, 2022 | LinksMedicus Free Medical News & Perspectives

RCT: Effect of early vs. standard approach to tracheostomy on functional outcome at 6 months among patients with severe stroke receiving mechanical ventilation.

6 May, 2022 | 11:13h | UTC

Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial – JAMA (free for a limited period)

Commentary on Twitter

In this study, among patients with severe stroke receiving mechanical ventilation, a strategy of early tracheostomy, compared with a standard approach to tracheostomy, did not significantly improve functional outcome at 6 months. https://t.co/bLZ4b6hBxr

— JAMA (@JAMA_current) May 4, 2022

Review: SARS-CoV-2 pathogenesis.

6 May, 2022 | 11:01h | UTC

SARS-CoV-2 pathogenesis – Nature Reviews Microbiology

Commentary on Twitter

A Review published in @NatureRevMicro explores recent clinical and experimental advances in understanding SARS-CoV-2 pathogenesis, interactions with host cells and the involvement of the immune system in the development of severe disease. https://t.co/GTm0BZ3ikH pic.twitter.com/jPXFU05Pwm

— Nature Portfolio (@NaturePortfolio) April 23, 2022

RCT: Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet.

6 May, 2022 | 11:05h | UTC

Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Safety of ezetimibe in lipid-lowering treatment: systematic review and meta-analysis of randomized controlled trials and cohort studies.

6 May, 2022 | 10:59h | UTC

Safety of ezetimibe in lipid-lowering treatment: systematic review and meta-analysis of randomised controlled trials and cohort studies – BMJ Medicine

PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations – The BMJ

PCSK9 inhibitors and ezetimibe with or without statin therapy for cardiovascular risk reduction: a systematic review and network meta-analysis – The BMJ

Commentary on Twitter

Read a new #systematicreview and meta-analysis of RCTs and cohort studies on the safety of #Ezetimibe in lipid-lowering treatment. ▶️ https://t.co/mr4H5MfVdP #VisualAbstract #RapidRecommendations @bmj_latest @theMAGICapp pic.twitter.com/OLg0HZr8D3

— BMJMedicine (@BMJMedicine) May 5, 2022

Long COVID: aiming for a consensus.

6 May, 2022 | 11:03h | UTC

Long COVID: aiming for a consensus – The Lancet Respiratory Medicine

Commentary on Twitter

There is an urgent need for unification of terminology for the sequelae of #SARSCoV2 infection to ensure that research is directed towards and translated into interventional trials to improve outcomes

NEW Comment—#LongCOVID: aiming for a consensushttps://t.co/dZO4rBVCSY pic.twitter.com/H5ezqL0RLb

— The Lancet Respiratory Medicine (@LancetRespirMed) May 5, 2022

Position statement on acute oxygen use in adults: ‘swimming between the flags’.

6 May, 2022 | 10:56h | UTC

Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’ – Respirology

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

Guideline Summary: New guidance on the perioperative management of diabetes.

6 May, 2022 | 10:55h | UTC

New guidance on the perioperative management of diabetes – Clinical Medicine Journal

Original Guideline: Perioperative Care of People with Diabetes Undergoing Surgery

Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings

Recent advances in diabetes treatments and their perioperative implications – Current Opinion in Anesthesiology

Perioperative Management of Oral Glucose-lowering Drugs in the Patient with Type 2 Diabetes – Anesthesiology

Intravenous contrast medium extravasation: systematic review and updated ESUR Contrast Media Safety Committee Guidelines.

6 May, 2022 | 10:53h | UTC

Intravenous contrast medium extravasation: systematic review and updated ESUR Contrast Media Safety Committee Guidelines – European Radiology

A Canadian national guideline on the neoadjuvant treatment of invasive breast cancer, including patient assessment, systemic therapy, and local management principles.

6 May, 2022 | 10:52h | UTC

A Canadian national guideline on the neoadjuvant treatment of invasive breast cancer, including patient assessment, systemic therapy, and local management principles – Breast Cancer Research and Treatment

Left ventricular remodeling post-myocardial infarction: pathophysiology, imaging, and novel therapies.

6 May, 2022 | 10:50h | UTC

Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies – European Heart Journal

Systematic Review: Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis.

6 May, 2022 | 10:47h | UTC

Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis – Cochrane Library

Summary: Cannabis and cannabinoids for people with multiple sclerosis – Cochrane Library

Commentary on Twitter

?A UK survey found that 1 in 5 people with #MS reported they used #Cannabis to manage symptoms.
? Does it work? Are there harms?
? Cochrane systematic review looks at 25 RCTs ➡️ https://t.co/HCt6Cx3suo #MedicalMarijuana #MultipleSclerosis pic.twitter.com/wjDTXXEciM

— The Cochrane Library (@CochraneLibrary) May 5, 2022

M-A: Wearable cuffless blood pressure monitoring devices.

6 May, 2022 | 10:48h | UTC

Wearable Cuffless Blood Pressure Monitoring Devices: A Systematic Review and Meta-Analysis – European Heart Journal – Digital Health

Commentary on Twitter

Wearable cuffless blood pressure monitoring devices: a systematic review and meta-analysis https://t.co/UP2M81OuzB #EHJDigital @BruiningNico @rafavidalperez @pauldub67 @clara_chow pic.twitter.com/8ouQvSH8mQ

— European Society of Cardiology Journals (@ESC_Journals) May 4, 2022

Systematic Review: Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression.

6 May, 2022 | 10:37h | UTC

Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review – Therapeutic Advances in Psychopharmacology

Discontinuing antidepressants: Pearls and pitfalls.

Review | Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop.

RCT: Maintenance vs. discontinuation of antidepressants in patients who felt well enough to discontinue antidepressant therapy.

A method for tapering antipsychotic treatment that may minimize the risk of relapse

Systematic Review: Managing Antidepressant Discontinuation

Randomized controlled trial: preventive cognitive therapy for prevention of depressive recurrence

M-A: Continuation of antidepressants vs. sequential psychological interventions to prevent relapse in depression.

Global inequalities in the double burden of malnutrition and associations with globalization: a multilevel analysis of Demographic and Healthy Surveys from 55 low-income and middle-income countries, 1992–2018.

6 May, 2022 | 10:38h | UTC

Global inequalities in the double burden of malnutrition and associations with globalisation: a multilevel analysis of Demographic and Healthy Surveys from 55 low-income and middle-income countries, 1992–2018 – The Lancet Global Health

Commentary: Associations between country-level macroeconomic factors and the double burden of malnutrition – The Lancet Global Health

Commentary from the author on Twitter (thread – click for more)

Our paper published today at @LancetGH looks at global inequalities of household-level double burden of malnutrition and associations with globalisation across 55 low- and middle-income countries https://t.co/uz5cnSEhuv @PHPE_IC @ImperialSPH @Imperial_PCPH 1/1

— Evi Seferidi (@e_seferidi) February 9, 2022