Daily Archives: May 2, 2022
AAP Guidance for pediatric end-of-life care.
2 May, 2022 | 00:51h | UTCGuidance for Pediatric End-of-Life Care – Pediatrics
Related Guidance: End of life care for infants, children and young people with life-limiting conditions: planning and management – National Institute for Health and Care Excellence
CDC Report: Acute hepatitis and adenovirus infection among children.
2 May, 2022 | 00:46h | UTCCommentaries:
CDC releases new clinical details in cases of unusual hepatitis in children – CNN
CDC report finds no Covid link in children’s hepatitis cases in Alabama – NBC News
Related:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentaries on Twitter
Report from Alabama of acute hepatitis & adenovirus infection in young kids, Oct 21-Feb 22. 9 cases, all had adenovirus, 5/5 tested +ve for Adenovirus type 41. No epi links found. All under 6 yrs of age, immunocompetent, & no significant comorbidities. https://t.co/DcgcfN3KHo
— Andrew Lee (@andrewleedr) April 29, 2022
New report from @CDCMMWR on the 9 episodes of severe acute hepatitis in children from Alabama
All 9 positive for Adenovirus on whole blood PCR (all 5 samples sequences were type 41)
None PCR positive for #SARSCoV2
HT @tonisoriano66 https://t.co/h9LmHeVHEf
— Alasdair Munro (@apsmunro) April 29, 2022
ATS/ERS/JRS/ALAT Guideline: Idiopathic pulmonary fibrosis and progressive pulmonary fibrosis in adults.
2 May, 2022 | 00:53h | UTC
Commentary on Twitter (thread – click for more)
?Finally out online: the latest multisocietal guidance defining progression in fibrotic lung disease? has arrived!
These long-awaited guidelines help better clarify disease definition and guide treatmenthttps://t.co/LVuoVdZRj2
What does this mean? Hang on to your hats! ?1/n pic.twitter.com/3jvFGSfSuI
— Deji Adegunsoye (@drdayjee) April 29, 2022
ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown etiology in children.
2 May, 2022 | 00:44h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Pfizer says COVID treatment Paxlovid fails to prevent infection of household members.
2 May, 2022 | 00:43h | UTCPfizer says COVID treatment Paxlovid fails to prevent infection of household members – Reuters
Commentary on Twitter
Pfizer Inc on Friday said a large trial found that its COVID-19 oral antiviral treatment Paxlovid was not effective at preventing coronavirus infection in people living with someone who had been exposed to the virus. https://t.co/95zphEYaxc
— Reuters Health (@Reuters_Health) April 29, 2022
RCT: Phentermine/Topiramate for the treatment of adolescent obesity.
2 May, 2022 | 00:41h | UTCPhentermine/Topiramate for the Treatment of Adolescent Obesity – NEJM Evidence
Commentary on Twitter
This RCT evaluated phentermine/topiramate in adolescents ages 12 to <17 yrs with high BMIs over a 56 week period. At both mid- and top-doses, treatment significantly reduced BMI and waist circumference compared to placebo. https://t.co/HbCZOAlZPf@PedsEndoSociety #PedsEndo2022 pic.twitter.com/nB5juqxyA0
— NEJM Evidence (@NEJMEvidence) April 30, 2022
RCT: Digital remote monitoring plus usual care vs. usual care in patients treated with oral anticancer agents.
2 May, 2022 | 00:37h | UTCDigital remote monitoring plus usual care versus usual care in patients treated with oral anticancer agents: the randomized phase 3 CAPRI trial – Nature Medicine (if the link is paywalled, try this one)
Commentary on Twitter
A phase 3 clinical trial evaluating the impact of a digital nurse navigator-led system in patients receiving oral #cancer treatment shows that remote monitoring with a smartphone results in improved patient experience & optimizes resources @GustaveRoussy https://t.co/N8fEXb00r7
— Nature Medicine (@NatureMedicine) April 26, 2022
RCT: Efficiency of electronic health record assessment of patient-reported outcomes after cancer immunotherapy.
2 May, 2022 | 00:36h | UTCInvited Commentary: An Assistive Electronic Patient-Reported Outcome Monitoring Intervention for Management of Immune-Related Toxic Effects—Moving Toward Efficiency and Scale – JAMA Network Open
Commentary on Twitter
This RCT aimed to compare the efficiency between ePRO and traditional follow up models in cancer immunotherapy among 278 patients from 28 hospitals, finding that an ePRO model can improve safety & QOL, and is less time consuming. https://t.co/KtpcNz0keb pic.twitter.com/EsmNyTkdfB
— JAMA Network Open (@JAMANetworkOpen) March 31, 2022
Consensus Recommendations: Quality standards for the management of non-alcoholic fatty liver disease.
2 May, 2022 | 00:21h | UTCRelated Guidelines:
Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports
NICE chronic primary pain guidelines: what the busy GP needs to know.
2 May, 2022 | 00:25h | UTCOriginal Guideline: Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain – National Institute for Health and Care Excellence
Review: Novel approaches to imaging the pulmonary vasculature and right heart.
2 May, 2022 | 00:29h | UTCNovel Approaches to Imaging the Pulmonary Vasculature and Right Heart – Circulation Research (free for a limited period)