Daily Archives: April 25, 2022
WHO: Multi-country – acute, severe hepatitis of unknown origin in children.
25 Apr, 2022 | 01:13h | UTCMulti-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
Commentaries:
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
At least one child has died from mystery strain of severe hepatitis, WHO confirms – The Guardian
Related:
CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention AND Guidance: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
AHA Scientific Statement: Engaging families in adult cardiovascular care.
25 Apr, 2022 | 01:09h | UTCTop Things to Know: Engaging Families in Adult Cardiovascular Care – American Heart Association
Commentary on Twitter
Our @American_Heart statement on Engaging Families in Adult Cardiovascular Care: A Scientific Statement From the American Heart Association that I had the honour of cochairing with Michael Goldfarb @mcgillu https://t.co/Tv6Mg15oI3 pic.twitter.com/WGtN6QUkuL
— Dr. Martha Gulati “Get Vaccinated Please” (@DrMarthaGulati) April 21, 2022
Under a Creative Commons Attribution‐NonCommercial‐NoDerivs License
NICE Guideline | Medicines associated with dependence or withdrawal symptoms: safe prescribing and withdrawal management for adults.
25 Apr, 2022 | 01:11h | UTC
Cohort Study: Association of the 2020 US presidential election with hospitalizations for acute cardiovascular conditions.
25 Apr, 2022 | 01:07h | UTCRelated:
Psychological Stress and Heart Disease: Fact or Folklore? – The American Journal of Medicine
Sudden Cardiac Death Triggered by an Earthquake – New England Journal of Medicine
Cardiovascular Events during World Cup Soccer – New England Journal of Medicine
Commentary from the author on Twitter (thread – click for more)
Found 42%⬆️in heart attacks days after 2020 US Presidential election ! Our study in 6,396,830 adults across California @JAMANetworkOpen https://t.co/4ikeNiWqkB with @MMeffordPhD & collaboration @HarvardChanSPH
Let's not underestimate the impact of emotional stress?on❤️
? pic.twitter.com/GVohHz1iGU— Jamal Rana, MD (@JamalRanaMD) April 20, 2022
Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study.
25 Apr, 2022 | 01:00h | UTC
Commentary on Twitter
Echocardiography in #COVID19 #ICU pts, ECHO-COVID study
♥︎ systolic dysfunction in ⅓: 23% LV (similar to septic cardiomyopathy), 22.5% RV (due to P overload)
♥︎ ACP in 17% (due to hypercapnia, PE, MV)
♥︎ ACP/age associated with in-ICU mortality
? https://t.co/NUlAZh9hHw pic.twitter.com/t17pNolFqy— Intensive Care Medicine (@yourICM) April 21, 2022
RCT: Segmentectomy resulted in better outcomes than lobectomy in small-sized peripheral non-small-cell lung cancer.
25 Apr, 2022 | 01:03h | UTCSegmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Cohort Study: COVID-19 vaccination during early pregnancy was not associated with increased risk of congenital fetal anomalies.
25 Apr, 2022 | 00:59h | UTCCommentaries:
COVID vaccine in early pregnancy not tied to birth defects – CIDRAP
No Sign That COVID Vaccine in Pregnancy Raises Birth Defect Risk – HealthDay
SARS-CoV-2 reinfections: overview of efficacy and duration of natural and hybrid immunity.
25 Apr, 2022 | 00:56h | UTCRelated Study:
Rates of COVID-19 Among Unvaccinated Adults With Prior COVID-19 – JAMA Network Open AND Commentaries: COVID-19 infection granted patients strong and long-lasting protection from reinfection – Providence Health & Services AND COVID-19 infection may offer similar immunity as vaccination – CIDRAP
RCT: Early surgery vs. exercise and education for meniscal tears in young adults.
25 Apr, 2022 | 00:51h | UTCEarly Surgery or Exercise and Education for Meniscal Tears in Young Adults – NEJM Evidence
Commentary:
Early Surgery Not Superior for Meniscal Tears in Young Adults – HealthDay
Commentary on Twitter
DREAM trial: In this pragmatic #RCT in active young adults with meniscal tears, early meniscal surgery was not superior to a strategy of supervised exercise therapy and education with the option of later surgery. @STSkou #OrthoTwitter #SurgTwitter https://t.co/TrnEUG98wP pic.twitter.com/V66ZbknksM
— NEJM Evidence (@NEJMEvidence) January 25, 2022
Consensus Statement: Management of patients with advanced prostate cancer.
25 Apr, 2022 | 00:50h | UTC
Commentary on Twitter
Management of Patients with Advanced Prostate Cancer: Report from the Advanced Prostate Cancer Consensus Conference 2021https://t.co/GjTGPx8IbN@APCCC_Lugano @Silke_Gillessen @AOmlin @AarmstrongDuke @piet_ost @Prof_IanD @DrSpratticus @charlesryanmd @Tilki_De @declangmurphy pic.twitter.com/FU0Fbjf8WZ
— European Urology (@EUplatinum) April 22, 2022
Systematic Review: The performance of wearable sensors in the detection of SARS-CoV-2 infection.
25 Apr, 2022 | 00:55h | UTC
Commentary on Twitter
A missed opportunity for Covid early detection and tracking, inexpensively, passively, at scalehttps://t.co/4cDxlps7AM systematic review of wearable sensors (smartwatch or fitness bands worn or owned by > 80 million Americans) @LancetDigitalH pic.twitter.com/sy1rArB5fE
— Eric Topol (@EricTopol) April 22, 2022
Under a (CC BY 4.0) License
Guideline: Substance use disorder in the anesthetist.
25 Apr, 2022 | 00:39h | UTC
Guidelines: Cutaneous lymphomas.
25 Apr, 2022 | 00:38h | UTC
RCT: Subacromial balloon spacer is not better than debridement only for irreparable rotator cuff tears of the shoulder.
25 Apr, 2022 | 00:27h | UTC
Cohort Study: Association of cumulative blood pressure with cognitive decline, dementia, and mortality.
25 Apr, 2022 | 00:35h | UTC
Review: The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up.
25 Apr, 2022 | 00:26h | UTC
Commentary on Twitter
The brain in #PICU
?vulnerable brains
?(age-appropriate) tools to assess neuro-function
?latest evidence related to neurocritical care monitoring in #PedsICU
?post discharge: PICS‑p & approaches for neurodevelopmental follow‑up #FOAMcc #FOAMped
? https://t.co/F8c1L7ysPy pic.twitter.com/zsXe3Tv5ns— Intensive Care Medicine (@yourICM) April 22, 2022
Consensus Statement: Ultrasonography of superficial soft-tissue masses.
25 Apr, 2022 | 00:36h | UTC
Opinion: Medicare’s bundled payment models—progress and pitfalls.
25 Apr, 2022 | 00:21h | UTCMedicare’s Bundled Payment Models—Progress and Pitfalls – JAMA (free for a limited period)
Cohort Study: New prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy.
25 Apr, 2022 | 00:20h | UTC
Commentary on Twitter
Developing a prediction model for ventricular arrhythmias in patients with ARVC. Can we do tailor our ICD decision making?#EHJ #ARVC https://t.co/KHAWCT37zR pic.twitter.com/3hAQa7FIB3
— EHJ Editor-in-Chief (@ehj_ed) April 22, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ licence
Point/Counterpoint: Should asymptomatic OSA be treated in patients with significant cardiovascular disease?
25 Apr, 2022 | 00:24h | UTCPOINT: Should Asymptomatic OSA Be Treated in Patients With Significant Cardiovascular Disease? Yes – CHEST
COUNTERPOINT: Should Asymptomatic OSA Be Treated in Patients With Significant Cardiovascular Disease? No – CHEST
Anticholinergic medications and dementia: should we be worried?
25 Apr, 2022 | 00:14h | UTCCommonly-prescribed drugs and dementia: should we be worried? – Evidently Cochrane
Original Review:
Related:
How well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative
Anticholinergic drugs and risk of dementia: case-control study – The BMJ
Commentary on Twitter
Commonly-prescribed drugs & dementia: should we be worried? https://t.co/pvWxT6q48Z A @CochraneUK blog: Jodi Watt (a researcher @UofGlasgow) explores the @CochraneDCIG evidence on whether #anticholinergics might increase people’s risk of future memory problems, or even #dementia
— The Cochrane Library (@CochraneLibrary) April 22, 2022
Perspective: Delivering precision oncology to patients with cancer.
25 Apr, 2022 | 00:13h | UTCDelivering precision oncology to patients with cancer – Nature Medicine (free for a limited period)
Commentary on Twitter
A Perspective in @NatureMedicine outlines the major challenges to the implementation of precision oncology and discusses critical steps toward resolving them. https://t.co/7l3WmFffn3 pic.twitter.com/oxFMZGZunf
— Nature Portfolio (@NaturePortfolio) April 24, 2022
Cohort Study: Assessment of a plasma amyloid probability score to estimate amyloid positron emission tomography findings among adults with cognitive impairment.
25 Apr, 2022 | 00:00h | UTC
Commentary on Twitter
This cohort study found a mass spectrometry-based blood test, measuring plasma Aβ42/40 & ApoE + age, accurately estimated brain amyloidosis via PET, and may help clinicians diagnose Alzheimer disease in patients with symptoms of cognitive impairment. https://t.co/VN7v0qf2uX
— JAMA Network Open (@JAMANetworkOpen) April 21, 2022
Teaching medical students to teach: a narrative review and literature-informed recommendations for student-as-teacher curricula.
25 Apr, 2022 | 00:03h | UTCTeaching Medical Students to Teach – Academic Medicine
Cohort Study: Progression to diabetes among older adults with Hemoglobin A1c–defined prediabetes was around 5% after a medium follow up of 2.3 years.
25 Apr, 2022 | 00:01h | UTCCommentaries:
How Often Does Prediabetes in Seniors Escalate to Full-Blown Disease? – MedPage Today (link to abstract – $ for full-text)
New Research Explores Diabetes Progression Rate in Older Adults with Prediabetes – HCP Livre
Related Study: Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine and Commentary: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health
Commentary on Twitter
This cohort study found that older adults with prediabetes showed higher progression to diabetes (5.3%) compared to prior studies. https://t.co/cHP7jyV7jT
— JAMA Network Open (@JAMANetworkOpen) April 21, 2022