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Daily Archives: March 30, 2022

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

30 Mar, 2022 | 10:44h | UTC

Second Booster Vaccine and Covid-19 Mortality in Adults 60 to 100 Years Old – Research Square

Commentaries:

Huge Study Finds Second COVID-19 Booster is ‘Life-saving’ for Over 60s – Health Policy Watch

Fourth COVID-19 vaccine dose substantially reduces mortality in the elderly – News Medical

 

Cohort Study: Short-term outcomes of corticosteroid monotherapy in multisystem inflammatory syndrome in children.

30 Mar, 2022 | 10:40h | UTC

Short-term Outcomes of Corticosteroid Monotherapy in Multisystem Inflammatory Syndrome in Children – JAMA Pediatrics

 

Commentary on Twitter

 

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

30 Mar, 2022 | 10:42h | UTC

U.S. approves second Covid-19 booster for people 50 and older – STAT

FDA OKs second COVID booster shot for older Americans – CIDRAP

See Guidance: Coronavirus (COVID-19) Update: FDA Authorizes Second Booster Dose of Two COVID-19 Vaccines for Older and Immunocompromised Individuals – U.S. Food & Drug Administration

 

Complicated and uncomplicated S. aureus bacteremia: an international Delphi survey among infectious diseases experts on definitions and treatment.

30 Mar, 2022 | 10:34h | UTC

Complicated and uncomplicated S. aureus bacteremia: an international Delphi survey among infectious diseases experts on definitions and treatment – Clinical Microbiology and Infection

 

The RECOVERY Trial – two years on.

30 Mar, 2022 | 10:38h | UTC

The RECOVERY Trial – two years on – University of Oxford

Related:

How the UK found the first effective Covid-19 treatment — and saved a million lives (about the RECOVERY trial and the effects of Dexamethasone)

Covid: The London bus trip that saved maybe a million lives (about the creation of the RECOVERY Trial)

Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 – Recovery Trial

[Preprint] RECOVERY trial shows Baricitinib reduces deaths in patients hospitalized with COVID-19.

RCT: CPAP improved outcomes in patients with acute hypoxemic respiratory failure due to COVID-19, but high-flow nasal oxygen was not better than conventional oxygen therapy.

RECOVERY Trial: In patients admitted to hospital with COVID-19, Colchicine did not reduce 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical ventilation or death.

RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.

RECOVERY Trial: Aspirin as an add-on therapy did not reduce mortality in patients hospitalized with COVID-19.

RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes

RECOVERY trial: Azithromycin not beneficial for patients admitted to hospital with COVID-19

[Preprint] RECOVERY trial finds Regeneron’s monoclonal antibody combination reduces deaths for hospitalized COVID-19 patients who have not mounted their own immune response.

RECOVERY trial: Effect of hydroxychloroquine in hospitalized patients with Covid-19

Randomized trial: Lopinavir–ritonavir not beneficial for patients admitted to hospital with COVID-19

 

Commentary on Twitter

 

The harms of postoperative antibiotic prophylaxis: a teachable moment.

30 Mar, 2022 | 10:36h | UTC

The Harms of Postoperative Antibiotic Prophylaxis: A Teachable Moment – JAMA Internal Medicine (free for a limited period)

 

M-A: Parenchymal lung abnormalities following hospitalization for COVID-19 and viral pneumonitis.

30 Mar, 2022 | 10:26h | UTC

Parenchymal lung abnormalities following hospitalisation for COVID-19 and viral pneumonitis: a systematic review and meta-analysis – Thorax

 

AHA/ASA Scientific Statement: Endovascular treatment and thrombolysis for acute ischemic stroke in patients with premorbid disability or dementia.

30 Mar, 2022 | 10:33h | UTC

Endovascular Treatment and Thrombolysis for Acute Ischemic Stroke in Patients With Premorbid Disability or Dementia: A Scientific Statement From the American Heart Association/American Stroke Association – Stroke

News Release: Stroke treatments safe and effective for people with existing disability or dementia – American Heart Association

 

Commentary on Twitter (thread – click for more)

 

Study shows overtreatment of diabetes common in nursing home residents with type 2 diabetes.

30 Mar, 2022 | 10:27h | UTC

Glycemic treatment deintensification practices in nursing home residents with type 2 diabetes – Journal of the American Geriatrics Society

Commentaries:

Overtreatment of T2DM Common Among VA Nursing Home Residents – HealthDay

Diabetes treatment deintensification uncommon in nursing home residents – medwire News

 

Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study.

30 Mar, 2022 | 10:24h | UTC

Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study – The BMJ

 

Commentary on Twitter

 

Extracorporeal life support organization guidelines for fluid overload, acute kidney injury, and electrolyte management.

30 Mar, 2022 | 10:20h | UTC

Extracorporeal Life Support Organization Guidelines for Fluid Overload, Acute Kidney Injury, and Electrolyte Management – ASAIO Journal

Related:

ELSO Guidelines for adult and pediatric extracorporeal membrane oxygenation circuits.

ELSO Guidelines for anticoagulation in adult and pediatric patients using extracorporeal membrane oxygenation (ECMO).

Guidelines for extracorporeal cardiopulmonary resuscitation in children and adults

 

Commentary on Twitter

 

EAU Guidelines on renal cell carcinoma.

30 Mar, 2022 | 10:19h | UTC

European Association of Urology Guidelines on Renal Cell Carcinoma: The 2022 Update – European Urology

 

Retrospective Cohort Study: Risks for anaphylaxis with intravenous iron formulations.

30 Mar, 2022 | 10:16h | UTC

Risks for Anaphylaxis With Intravenous Iron Formulations: A Retrospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Risk of Severe Allergic Reaction Higher with Two Intravenous Iron-Boosting Products – Rutgers University

Commentary: Risks for Anaphylaxis Compared Among IV Iron Products – HealthDay

 

Review: Sudden cardiac death in congenital heart disease.

30 Mar, 2022 | 10:17h | UTC

Sudden cardiac death in congenital heart disease – European Heart Journal

 

Commentary on Twitter

 

Systematic Review: Interventions for reducing inflammation in familial Mediterranean fever.

30 Mar, 2022 | 10:13h | UTC

Interventions for reducing inflammation in familial Mediterranean fever – Cochrane Library

Summary: Medicines for reducing inflammation in people with familial Mediterranean fever – Cochrane Library

 

Systematic Review: Probiotics for treatment of chronic constipation in children.

30 Mar, 2022 | 10:12h | UTC

Probiotics for treatment of chronic constipation in children – Cochrane Library

Summary: Probiotics for treatment of chronic constipation in children – Cochrane Library

 

Systematic Review: Pregabalin add‐on for drug‐resistant focal epilepsy.

30 Mar, 2022 | 10:10h | UTC

Pregabalin add‐on for drug‐resistant focal epilepsy – Cochrane Library

Summary: Pregabalin add-on for drug-resistant focal epilepsy – Cochrane Library

 

End-of-life care in the cardiac intensive care unit: a contemporary view from the Critical Care Cardiology Trials Network (CCCTN) Registry.

30 Mar, 2022 | 10:08h | UTC

End-of-life care in the cardiac intensive care unit: a contemporary view from the Critical Care Cardiology Trials Network (CCCTN) Registry – European Heart Journal. Acute Cardiovascular Care

 

Commentary on Twitter

 

Cohort Study: Risk factors for complications after surgery for pancreatic neuroendocrine tumors.

30 Mar, 2022 | 10:03h | UTC

Risk factors for complications after surgery for pancreatic neuroendocrine tumors – Surgery

 

Commentary on Twitter

 

Safety and economic analysis of selective histopathology following cholecystectomy: multicenter, prospective, cross-sectional study.

30 Mar, 2022 | 09:59h | UTC

Safety and economic analysis of selective histopathology following cholecystectomy: multicentre, prospective, cross-sectional FANCY study – British Journal of Surgery

 

Commentary on Twitter

 

What to expect when women with axial spondyloarthritis are expecting: Prevalence of complications of pregnancies in women with axial spondyloarthritis.

30 Mar, 2022 | 10:01h | UTC

What to expect when women with axial spondyloarthritis are expecting: Prevalence of complications of pregnancies in women with axial spondyloarthritis – Seminars in Arthritis and Rheumatism

 

Commentary on Twitter

 

Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019.

30 Mar, 2022 | 09:55h | UTC

Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019 – The Lancet Child & Adolescent Health

Invited Commentary: 30-year NCD burden data for EU adolescents merit close attention – The Lancet Child & Adolescent Health (free registration required)

 

Commentary on Twitter (thread – click for more)

 

Systematic Review: The global gap in treatment coverage for major depressive disorder in 84 countries from 2000–2019.

30 Mar, 2022 | 09:49h | UTC

The global gap in treatment coverage for major depressive disorder in 84 countries from 2000–2019: A systematic review and Bayesian meta-regression analysis – PLOS Medicine

Commentary: PLOS Medicine: Study highlights worldwide disparities in treatment rates for major depressive disorder – Institute for Health Metrics and Evaluation

 

M-A: Effectiveness of cognitive–behavioral therapies of varying complexity in reducing depression in adults.

30 Mar, 2022 | 09:46h | UTC

Effectiveness of cognitive–behavioural therapies of varying complexity in reducing depression in adults: systematic review and network meta-analysis – British Journal of Psychiatry (link to abstract – $ for full-text)

News Release: Enhanced CBT can radically reduce long-term depression, finds study – University of Manchester

 

AI estimation of gestational age from blind ultrasound sweeps in low-resource settings.

30 Mar, 2022 | 09:53h | UTC

AI Estimation of Gestational Age from Blind Ultrasound Sweeps in Low-Resource Settings – NEJM Evidence

 

Commentary on Twitter

 

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