Daily Archives: March 24, 2022
RCT: Among premature infants with a gestational age of less than 30 weeks and intubated for at least 7 days at 14 to 28 days, hydrocortisone did not improve survival without bronchopulmonary dysplasia.
24 Mar, 2022 | 09:58h | UTCHydrocortisone to Improve Survival without Bronchopulmonary Dysplasia – New England Journal of Medicine (link to abstract – $ for full-text)
See also: Visual Abstract
Related:
State of the Art Review: Diagnosis and management of bronchopulmonary dysplasia.
ERS Guideline on Long-term Management of Children with Bronchopulmonary Dysplasia
Commentary on Twitter
In this trial involving preterm infants, there was little difference in survival without bronchopulmonary dysplasia or in the occurrence of neurodevelopmental impairment with hydrocortisone as compared with placebo. https://t.co/wzGQ1gohjA pic.twitter.com/yfrIaG3JLv
— NEJM (@NEJM) March 23, 2022
Observational study suggests antidopaminergic antiemetics (domperidone, metopimazine, and metoclopramide) are associated with increased stroke risk.
24 Mar, 2022 | 09:51h | UTCNews Release: Widely used nausea drugs linked to heightened risk of stroke – BMJ
RCT: Single-dose Liposomal Amphotericin B treatment for Cryptococcal Meningitis.
24 Mar, 2022 | 09:56h | UTCSingle-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Cryptococcal meningitis is a major complication of HIV infection. Single-dose liposomal amphotericin B combined with flucytosine and fluconazole was noninferior to the WHO-recommended treatment and was associated with fewer adverse events. https://t.co/cg9DqSDhyN pic.twitter.com/SrKx4tDaph
— NEJM (@NEJM) March 23, 2022
Test-negative, case-control study: effectiveness of the Pfizer vaccine against COVID-19 in adolescents.
24 Mar, 2022 | 09:44h | UTCEffectiveness of BNT162b2 against COVID-19 in adolescents – The Lancet Infectious Diseases
Commentary on Twitter
Our paper on #COVID19 vaccine effectiveness in teenagers (12-17y) is published @TheLancetInfDis. Rapid waning of protection against symptomatic disease, esp with omicron. Vaccines did reduce delta hospitalisations but too early to assess omicron effects
— Shamez Ladhani (@ShamezLadhani) March 23, 2022
RCT: Safety and efficacy of a third dose of the Pfizer Covid-19 vaccine during the Delta wave.
24 Mar, 2022 | 09:46h | UTCSafety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine – New England Journal of Medicine
Commentary on Twitter
A third dose of the BNT162b2 vaccine administered a median of 10.8 months after the second dose provided 95.3% efficacy against Covid-19 as compared with two doses. #COVID19 #IDTwitter https://t.co/IeHOgVhU8a pic.twitter.com/wValXSdyHX
— NEJM (@NEJM) March 23, 2022
Systematic Review: Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19.
24 Mar, 2022 | 08:53h | UTCCommentaries:
Simple home oxygen monitors signal when to seek COVID care – CIDRAP
RCT: Awake prone positioning did not improve outcomes in patients with moderate hypoxemia due to covid-19.
24 Mar, 2022 | 09:48h | UTCEditorial: Awake prone positioning for patients with covid-19
News Release: Lying prone long enough to improve outcomes is difficult for many covid-19 patients – BMJ
Estimating overdiagnosis of melanoma using trends among black and white patients in the US.
24 Mar, 2022 | 08:52h | UTCEstimating Overdiagnosis of Melanoma Using Trends Among Black and White Patients in the US – JAMA Dermatology (link to abstract – $ for full-text)
Commentary: Deadly form of skin cancer ‘overdiagnosed’ in some patients, study finds – UPI
Commentary from the author on Twitter (thread – click for more)
The wildest thing about this paper is we wrote it in 2017, then shelved it because of the initial push back in peer review. This experience taught me A LOT about when colleagues are ready to accept ideas that challenge their thinking. ?
1/9 https://t.co/hXDURXkwju— Ade Adamson, MD MPP (@AdeAdamson) March 20, 2022
Guideline: Evaluation and medical management of the kidney stone patient.
24 Mar, 2022 | 08:46h | UTCRelated Guidelines:
RCT: Multivitamins not beneficial for the prevention of cancer.
24 Mar, 2022 | 08:49h | UTCCommentary: Daily Multivitamin Does Not Cut Cancer Incidence in Older Adults – HealthDay
[News release – not published yet] RCT: Minimally invasive approach to hysterectomy in cervical cancer is associated with poorer disease-free survival than open surgery.
24 Mar, 2022 | 08:47h | UTC
Consensus Statement | Minimally-invasive treatments for benign thyroid nodules: recommendations for information to patients and referring physicians.
24 Mar, 2022 | 08:42h | UTC
Multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer.
24 Mar, 2022 | 08:45h | UTC
Position Paper | Individualized treatment of differentiated thyroid cancer: The value of surgery in combination with radioiodine imaging and therapy.
24 Mar, 2022 | 08:34h | UTC
FIGO recommendations on the management of postpartum hemorrhage 2022.
24 Mar, 2022 | 08:38h | UTCFIGO recommendations on the management of postpartum hemorrhage 2022 – Gynecology & Obstetrics
Related:
[Abstract Only] Meta-Analysis: Uterine Balloon Tamponade for the Treatment of Postpartum Hemorrhage
Consensus Statement: Prevention and Treatment of Postpartum Hemorrhage
WHO Guideline: Uterotonics for the Prevention of Postpartum Hemorrhage
M-A: The impact of cold ischemia time on outcomes of living donor kidney transplantation.
24 Mar, 2022 | 08:33h | UTC
Oral dextrose gel for the treatment of hypoglycemia in newborn infants.
24 Mar, 2022 | 08:28h | UTCOral dextrose gel for the treatment of hypoglycaemia in newborn infants – Cochrane Library
Systematic Review: Duct‐to‐mucosa vs. other types of pancreaticojejunostomy for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy.
24 Mar, 2022 | 08:27h | UTC
M-A: Global prevalence and trends in hypertension and type 2 diabetes mellitus among slum residents.
24 Mar, 2022 | 08:30h | UTC
Higher cigarette taxes could reduce child deaths, first global estimates suggest.
24 Mar, 2022 | 08:25h | UTCNews Release: Higher cigarette taxes reduce child deaths, first global estimates suggest – Imperial College London
Original Study: Cigarette taxation and neonatal and infant mortality: A longitudinal analysis of 159 countries – PLOS Global Public Health
Review: Are we overlooking alcohol use by younger children?
24 Mar, 2022 | 08:21h | UTCAre we overlooking alcohol use by younger children? – BMJ Paediatrics Open
Delirium linked to increase in hospital deaths.
24 Mar, 2022 | 08:24h | UTCNews Release: Delirium linked to increase in hospital deaths – University of Edinburgh
Commentary on Twitter
Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions.
Thank you @emmavardy2 @A_MacLullich @atula_tweets Michael Cheng, Temi Ibitoye https://t.co/bBjBQ3xpTd— Age_and_Ageing (@Age_and_Ageing) March 16, 2022
Study suggests an association of strabismus with mood disorders, schizophrenia, and anxiety disorders among children.
24 Mar, 2022 | 08:14h | UTCAssociation of Strabismus With Mood Disorders, Schizophrenia, and Anxiety Disorders Among Children – JAMA Pediatrics (link to abstract – $ for full-text)
Commentary: Moderate Associations ID’d for Strabismus, Mental Health Disorders – HealthDay
Commentary on Twitter
A study evaluating over 10 million insurance claims, found an association between having a diagnosis of strabismus and anxiety disorder, schizophrenia, bipolar disorder, and depressive disorder, but not substance-use disorder. https://t.co/MkyF26QJ3U
— JAMAOphthalmology (@JAMAOphth) March 10, 2022
Clinical approach to vision loss: a review for general physicians.
24 Mar, 2022 | 08:09h | UTCClinical approach to vision loss: a review for general physicians – Clinical Medicine Journal
Biomarkers may be an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica.
24 Mar, 2022 | 08:17h | UTCCommentary: Biomarkers may improve giant cell arteritis diagnosis – medwireNews
Commentary on Twitter
In our newest paper we investigated biomarkers that aid the diagnosis of Giant Cell Arteritis versus PMR or other mimicing conditions. This time, we worked together with our colleagues in Aarhus, Denmark to measure the biomarkers in 2 independent cohortshttps://t.co/d6PWsGSl2H
— Yannick van Sleen (@SleenYannick) March 11, 2022