Daily Archives: March 15, 2022 | LinksMedicus Free Medical News & Perspectives

[Preprint] High vaccine effectiveness against severe Covid-19 in the elderly in Finland before and after the emergence of Omicron.

15 Mar, 2022 | 09:59h | UTC

High vaccine effectiveness against severe Covid-19 in the elderly in Finland before and after the emergence of Omicron – medRxiv

Commentary on Twitter

The acid test for Covid vaccines are protection of the elderly. New data from ~900,000 Finns age 70+ show how 3 shots achieved 96% effectiveness vs hospitalization, before and after Omicron, and even higher vs ICU need https://t.co/TQOQV4SL9a Spikevax=Moderna; Comirnaty=Pfizer pic.twitter.com/mtUCqne1dT

— Eric Topol (@EricTopol) March 14, 2022

COVID-19 and resilience of healthcare systems in ten countries.

15 Mar, 2022 | 10:02h | UTC

COVID-19 and resilience of healthcare systems in ten countries – Nature

M-A: Evaluating the association between LDL Cholesterol reduction and relative and absolute effects of statin treatment.

15 Mar, 2022 | 10:04h | UTC

Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)

Commentary from the author: Benefits of statins may have been overstated – new study – The Conversation

Commentary on Twitter

Our study in @JAMAInternalMed asked 2 questions 1. Is reducing one’s ‘bad’ cholesterol was associated with a proportional reduction in death, heart attack and stroke? 2. What's the absolute reduction in risk from taking statins? https://t.co/Zwh7LmUD0e

— Dr Paula Byrne (@pbyrne82) March 14, 2022

Review | Resistance exercise as a treatment for sarcopenia: prescription and delivery.

15 Mar, 2022 | 09:55h | UTC

Resistance exercise as a treatment for sarcopenia: prescription and delivery – Age and Ageing

Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists.

15 Mar, 2022 | 09:51h | UTC

Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists – La Radiologia Medica

Caring for older adults during the COVID-19 pandemic.

15 Mar, 2022 | 09:48h | UTC

Caring for older adults during the COVID-19 pandemic – Clinical Microbiology and Infection

Retrospective Cohort: Asthma in children and adolescents is not associated with increased risk of SARS-CoV-2 infection.

15 Mar, 2022 | 08:55h | UTC

Asthma and the Risk of SARS-CoV-2 Infection Among Children and Adolescents – Pediatrics

Commentary: Kids with asthma not at higher risk of COVID-19, study finds – CIDRAP

We expected people with asthma to fare worse during COVID. Turns out they’ve had a break.

M-A: Asthma does not increase the risk of infection, hospitalization, ICU admission, and mortality from COVID-19

Systematic review: No evidence that patients with asthma are at increased risk of COVID-19 diagnosis, hospitalization or death

Asthma in COVID-19 hospitalizations: An overestimated risk factor?

Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease.

15 Mar, 2022 | 08:49h | UTC

Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis – The Lancet Respiratory Medicine

Commentary on Twitter

NEW Research—LMICs account for more than 3/4 of global #COPD cases. W/ increased life expectancy in the majority of LMICs, prevalence of COPD in these countries is set to increase.

Study from NIHR @RESPIREGlobal Respiratory Health Unit https://t.co/KD1OSHuMAr pic.twitter.com/Mfm1uJ2tBm

— The Lancet Respiratory Medicine (@LancetRespirMed) March 11, 2022

Two years later, coronavirus evolution still surprises experts. Here’s why.

15 Mar, 2022 | 08:52h | UTC

Two years later, coronavirus evolution still surprises experts. Here’s why. – National Geographic

Clinical practice guidelines for pain, agitation, delirium, immobility, and sleep disturbance in the intensive care unit.

15 Mar, 2022 | 08:45h | UTC

2021 KSCCM clinical practice guidelines for pain, agitation, delirium, immobility, and sleep disturbance in the intensive care unit – Acute and Critical Care

‘We suppressed our scientific imagination’: four experts examine the big successes and failures of the COVID response so far.

15 Mar, 2022 | 08:47h | UTC

‘We suppressed our scientific imagination’: four experts examine the big successes and failures of the COVID response so far – The Conversation

Open Label RCT: Azithromycin for poorly controlled asthma in children.

15 Mar, 2022 | 08:39h | UTC

Azithromycin for Poorly Controlled Asthma in Children: A randomized controlled trial – CHEST (link to abstract – $ for full-text)

Commentary: Adding azithromycin to standard care improves asthma control, exacerbations in children – Healio

NCCN Guideline: T-Cell Lymphomas.

15 Mar, 2022 | 08:41h | UTC

T-Cell Lymphomas, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

RCT: A preconception lifestyle intervention for weight loss did not improve fertility rates among women with obesity and infertility.

15 Mar, 2022 | 08:34h | UTC

Effects of preconception lifestyle intervention in infertile women with obesity: The FIT-PLESE randomized controlled trial – PLOS Medicine

Commentary: Weight loss doesn’t help pregnancy chances, study finds – University of Virginia Health System

Guideline: The use of antenatal corticosteroids for fetal maturation.

15 Mar, 2022 | 08:43h | UTC

The use of antenatal corticosteroids for fetal maturation: clinical practice guideline by the WAPM-World Association of Perinatal Medicine and the PMF-Perinatal Medicine foundation – Journal of Perinatal Medicine

Guide to statistics and methods: collider bias.

15 Mar, 2022 | 08:30h | UTC

Collider Bias – JAMA (free for a limited period)

Single-center RCT: Accessible Hepatitis C care for people who inject drugs.

15 Mar, 2022 | 08:36h | UTC

Accessible Hepatitis C Care for People Who Inject Drugs: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentary on Twitter

This randomized clinical trial found that the accessible care model provides a framework for developing treatment programs geared toward engaging, treating, and curing hepatitis C virus infection in people who inject drugs. https://t.co/zauS1gtPgO

— JAMA Internal Medicine (@JAMAInternalMed) March 14, 2022

Cohort Study: Evaluating rates of recurrent ischemic stroke among young adults with embolic stroke of undetermined source.

15 Mar, 2022 | 08:33h | UTC

Evaluating Rates of Recurrent Ischemic Stroke Among Young Adults With Embolic Stroke of Undetermined Source: The Young ESUS Longitudinal Cohort Study – JAMA Neurology (free for a limited period)

Commentary: Embolic Stroke of Undetermined Source in the Young: Low Recurrence, but Few Answers — Growing evidence that role of atrial fibrillation is less important than originally believed – MedPage Today (free registration required)

Commentary on Twitter

Study found relatively low rate of subsequent ischemic stroke and new onset #AF in young patients with ESUS compared to older patients. History of stroke/TIA, diabetes, and coronary artery disease were predictive of recurrence. https://t.co/mzTgMkVFGN @PereraKanjana

— JAMA Neurology (@JAMANeuro) March 14, 2022