Daily Archives: March 7, 2022
RCT: In patients with stable chest pain with intermediate pretest probability of obstructive coronary artery disease, an initial diagnostic imaging strategy based on CT angiography resulted in similar risks of major adverse cardiovascular events compared to invasive coronary angiography.
7 Mar, 2022 | 00:55h | UTCCT or Invasive Coronary Angiography in Stable Chest Pain – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: DISCHARGE Hailed as a Big Step Forward for CTA in Stable Chest Pain – TCTMD
Commentary on Twitter
Among patients referred for invasive coronary angiography because of stable chest pain and intermediate pretest probability of CAD, the risk of major adverse CV events was similar in the CT group and the ICA group. #ECR22 https://t.co/KnuQo0juxE pic.twitter.com/Sf70dqfgKP
— NEJM (@NEJM) March 4, 2022
RCT: Anterior–lateral electrode position is more effective compared to anterior–posterior electrode position for cardioverting atrial fibrillation.
7 Mar, 2022 | 00:45h | UTCCommentary: Anterior-Lateral or Anterior-Posterior Pads for A-fib Cardioversion? – JournalFeed
Commentary on Twitter
#OriginalResearch In this multicenter RCT of 468 patients, anterior-lateral electrode position was more effective than anterior-posterior electrode position for ⚡cardioversion of #Afib #AHAJournalshttps://t.co/XJlxe7e7Ed pic.twitter.com/hA4wGb6Pak
— Circulation (@CircAHA) November 24, 2021
Systematic Review: Anticoagulants for people hospitalized with COVID‐19.
7 Mar, 2022 | 00:48h | UTCAnticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Related: Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.
COVID-19: How Omicron overtook Delta in three charts.
7 Mar, 2022 | 00:46h | UTCCOVID-19: How Omicron overtook Delta in three charts – Nature
Systematic Review: Prediction of good neurological outcome in comatose survivors of cardiac arrest.
7 Mar, 2022 | 00:40h | UTC
Commentary on Twitter
Predicting good neuro outcome in comatose cardiac arrest survivors? Look at
? GCS motor 4/5
? normal NSE
? SSEP N20 wave amplitude > 4 μV or continuous EEG background without discharges
? no diffusion restriction in cortex or deep grey matter on MRI
SR https://t.co/ixkMvErdux pic.twitter.com/GjeuTLgDlb— Intensive Care Medicine (@yourICM) March 4, 2022
Ten myths about albumin.
7 Mar, 2022 | 00:44h | UTCTen myths about albumin – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
Albumin, 10 myths
1️⃣leaks into interstitium
2️⃣ ⬇️volume expansion vs artificial colloids
3️⃣ ⬇️AKI
4️⃣ sepsis: ⬆️survival
5️⃣ ⬆️diuretics effects
6️⃣RRT: ⬆️ fluid removal
7️⃣cirrhosis: ⬇️mortality
8️⃣TBI: ⬆️mortality
9️⃣correcting hypoalb ⬇️mortality
? ⬆️NaCl
? https://t.co/nGOHOLYRqY pic.twitter.com/YroygQNNUk— Intensive Care Medicine (@yourICM) March 5, 2022
Review articles: Cutaneous manifestations of SARS-CoV-2 infection.
7 Mar, 2022 | 00:38h | UTCCutaneous Manifestations of SARS-CoV-2 Infection – American Journal of Clinical Dermatology
Common skin signs of COVID-19 in adults: An update – Cleveland Clinic Journal of Medicine
The Lancet Series: Ageing with HIV.
7 Mar, 2022 | 00:35h | UTCHomepage: Ageing with HIV
Editorials:
Series:
Delayed presentation of HIV among older individuals: a growing problem
How health systems can adapt to a population ageing with HIV and comorbid disease
Biological ageing with HIV infection: evaluating the geroscience hypothesis
New research finds breast cancer overdiagnosis not as common as previously thought.
7 Mar, 2022 | 00:36h | UTCEstimation of Breast Cancer Overdiagnosis in a U.S. Breast Screening Cohort – Annals of Internal Medicine (link to abstract – $ for full-text)
Breast cancer overdiagnosis may not happen as frequently as previously thought – ACP Internist
RCT: Efficacy and safety of switching to the 2-drug regimen Dolutegravir/Lamivudine vs. continuing a 3- or 4-Drug regimen for maintaining virologic suppression in adults living with HIV-1.
7 Mar, 2022 | 00:32h | UTC
Over 1 billion people projected to live with obesity by 2030, warns new World Obesity Atlas.
7 Mar, 2022 | 00:12h | UTCReport: Obesity Atlas 2022 – Global Obesity Observatory
WHO global standard for safe listening venues and events.
7 Mar, 2022 | 00:17h | UTCWHO global standard for safe listening venues and events – World Health Organization
Q&A: Deafness and hearing loss: Safe listening – World Health Organization
Commentaries:
WHO Releases New Noise Standard for Public Venues to Tackle Hearing Loss – Health Polity Watch
Obesity rates likely to double by 2030 with highest rises in lower-income countries – The Guardian
Commentary on Twitter (thread – click for more)
Today is #WorldHearingDay!
1 in 2 young people are is at risk of hearing loss from prolonged and excessive exposure to loud music and other recreational sounds.
Find out how you can protect your hearing https://t.co/0bvXNbYgFw#SafeListening
— World Health Organization (WHO) (@WHO) March 2, 2022
WSES/GAIS/WSIS/SIS-E/AAST global clinical pathways for patients with skin and soft tissue infections.
7 Mar, 2022 | 00:09h | UTC
WSES guidelines on blunt and penetrating bowel injury: diagnosis, investigations, and treatment.
7 Mar, 2022 | 00:11h | UTC
M-A: Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma.
7 Mar, 2022 | 00:07h | UTC
Commentary from the author on Twitter (thread – click for more)
In this global study of NAFLD-related HCC, we determine:
1.Prevalence
2.Clinical characteristics
3.% cirrhosis
4.Surveillance
5.Treatment allocation
6.Outcomes#LiverCancerSIG #LivertwitterFree to read @TheLancetOncol https://t.co/vwAeicpWxq
1/n pic.twitter.com/gM1BHVSwXl
— Daniel Huang (@DrHuangDQ) March 4, 2022
Multiparametric ultrasound vs. multiparametric MRI to diagnose prostate cancer (CADMUS): a prospective, multicentre, paired-cohort, confirmatory study.
7 Mar, 2022 | 00:04h | UTCMultiparametric ultrasound versus multiparametric MRI to diagnose prostate cancer (CADMUS): a prospective, multicentre, paired-cohort, confirmatory study – The Lancet Oncology (link to abstract – $ for full-text)
News Release: Ultrasound scan can diagnose prostate cancer – Imperial College London
Commentary on Twitter
In a prospective confirmatory study comparing multiparametric US vs MRI for prostate cancer detection in 306 men with an abnormal PSA or DRE findings, US detected 4.3% fewer clinically significant cancers despite 11.1% more pts being referred for a biopsy: https://t.co/ZFkiUTFJ5Y
— NatureRevClinOncol (@NatRevClinOncol) March 3, 2022
Lab study tested an extensive range of possibly effective drug combinations in breast, colon, and pancreatic cancer cells.
7 Mar, 2022 | 00:03h | UTCEffective drug combinations in breast, colon and pancreatic cancer cells – Nature
Commentaries:
New drug combinations found for resistant cancers – Wellcome Trust Sanger Institute
Study predicts treatment combinations for resistant cancers – Frontline Genomics
Arterial blood gas analysis: as safe as we think? A multicentre historical cohort study.
7 Mar, 2022 | 00:00h | UTCArterial blood gas analysis: as safe as we think? A multicentre historical cohort study – ERJ Open