Daily Archives: March 4, 2022
[Preprint] RECOVERY trial shows Baricitinib reduces deaths in patients hospitalized with COVID-19.
4 Mar, 2022 | 10:09h | UTCNews Release: RECOVERY trial shows Baricitinib reduces deaths in patients hospitalised with COVID-19 – University of Oxford
Commentaries:
Arthritis drug reduces mortality in severe COVID-19, huge clinical trial finds – Science
Another life-saving Covid drug identified – BBC
Related:
WHO recommends two new drugs (Baricitinib and Sotrovimab) to treat COVID-19.
RCT: Baricitinib reduced mortality in hospitalized adults with COVID-19.
Randomized trial: Baricitinib plus remdesivir reduce recovery time in patients with COVID-19
Commentary from the author on Twitter (thread – click for more)
RECOVERY pre-print: Baricitinib
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis https://t.co/g0cNjaBzEL
— Martin Landray (@MartinLandray) March 3, 2022
Variation in the COVID-19 infection–fatality ratio by age, time, and geography during the pre-vaccine era: a systematic analysis.
4 Mar, 2022 | 10:07h | UTCInvited Commentary: Understanding of COVID-19 from infection–fatality ratio – The Lancet
Quantifying the effects of the COVID-19 pandemic on gender equality on health, social, and economic indicators.
4 Mar, 2022 | 10:04h | UTCCommentaries:
Gender equality and COVID-19: act now before it is too late – The Lancet
Commentary on Twitter (thread – click for more)
NEW—The social & economic effects of the #COVID19 pandemic threaten to reverse progress in #GenderEquality by widening gender gaps that already existed in employment, education & gender-based violence, according to our new study in @TheLancet
?https://t.co/TCXStNPgRV pic.twitter.com/RAuDBRaNS7— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) March 3, 2022
Updated WHO guidance conditionally recommends Molnupiravir for patients with non-severe covid-19 at highest risk of hospitalization.
4 Mar, 2022 | 09:57h | UTCBMJ News Release: WHO recommends antiviral drug for patients with non-severe covid-19 at highest risk of hospital admission – BMJ
WHO News Release: WHO updates its treatment guidelines to include molnupiravir
See updated guidance: A living WHO guideline on drugs for covid-19 – BMJ
Related:
Editorial (just published): Molnupiravir’s authorisation was premature – The BMJ
FDA panel narrowly recommends authorization of first antiviral pill to treat COVID.
8 lingering questions about the new Covid pills from Merck and Pfizer.
The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.
Merck to allow other nations to produce new COVID-19 antiviral.
Video: Merck’s Covid pill could transform treatment. Here’s how it works.
How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.
What we know — and don’t know — about Merck’s new Covid-19 pill.
Merck’s Covid-19 pill is great news but may not be a game-changer.
Video | A Pill For COVID? A Doctor Explains Molnupiravir.
M-A: Efficacy of covid-19 vaccines in immunocompromised patients.
4 Mar, 2022 | 10:01h | UTCNews Release: Study suggests additional covid-19 vaccine doses for immunocompromised patients – BMJ Newsroom
Related: Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review.
Commentary on Twitter
NEW RESEARCH: Additional doses of covid-19 vaccine are recommended for immunocompromised patients, especially for organ transplant recipients who are least able to make antibodies to fight off coronavirus, suggests new research https://t.co/l2IWfSb0zd @sundar__raghav
— The BMJ (@bmj_latest) March 3, 2022
Viewpoint: Understanding and communicating uncertainty in achieving diagnostic excellence.
4 Mar, 2022 | 09:56h | UTCUnderstanding and Communicating Uncertainty in Achieving Diagnostic Excellence – JAMA (free for a limited period)
Cohort Study: Association between screen time exposure in children at 1 year of age and autism spectrum disorder at 3 years of age.
4 Mar, 2022 | 09:54h | UTCCommentary: Screen Time Linked to Autism Spectrum Disorder in Boys – HealthDay
Related:
M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.
Media and Young Minds – American Academy of Pediatrics
Systematic Review: Arthroscopic surgery provides little or no clinically important benefit for patients with degenerative knee disease.
4 Mar, 2022 | 09:53h | UTCSummary: Arthroscopic surgery for degenerative knee disease – Cochrane Library
Related:
Guideline: Arthroscopic Meniscal Surgery
Study: Adverse Outcomes After Arthroscopic Partial Meniscectomy
Pre-post study: The introduction of a text-message alert system to alert volunteers close to a cardiac arrest patient at home was associated with increased survival to hospital discharge.
4 Mar, 2022 | 09:44h | UTC
Commentary on Twitter
For patients with a cardiac arrest at home, an alert system that includes nearby volunteers activated by the ambulance dispatch centre and many easily accessible AEDs saves lives https://t.co/0jfD9LsKip @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/pjPk3NJDla
— European Society of Cardiology Journals (@ESC_Journals) December 20, 2021
A guideline for the outpatient management of glycemic control in people with cancer.
4 Mar, 2022 | 08:56h | UTC
Randomized Diagnostic Study: home blood pressure measurements correlate better with 24-h ambulatory monitoring measurements compared to clinic, and kiosk measurements.
4 Mar, 2022 | 09:41h | UTC
ACR Guidelines for the Treatment of Juvenile Idiopathic Arthritis.
4 Mar, 2022 | 08:58h | UTC
AAP Clinical Report: Recognition and management of cardiovascular insufficiency in the very low birth weight newborn.
4 Mar, 2022 | 08:54h | UTC
Risk of cancer with angiotensin-receptor blockers increases with cumulative exposure: Meta-regression analysis of randomized trials.
4 Mar, 2022 | 08:49h | UTCCommentary: ARBs and Cancer Risk: New Meta-Analysis Raises Questions Again – Medscape (free registration required)
JCS/JHRS guideline focused update on non-pharmacotherapy of cardiac arrhythmias.
4 Mar, 2022 | 08:51h | UTC
Systematic Review: Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis.
4 Mar, 2022 | 08:46h | UTC
Nudging within learning health systems: next generation decision support to improve cardiovascular care.
4 Mar, 2022 | 08:50h | UTC
Commentary on Twitter
Nudging within learning health systems: next generation decision support to improve cardiovascular care https://t.co/TbPSqBDZVR @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/6yJB9Rcu92
— European Society of Cardiology Journals (@ESC_Journals) March 3, 2022
Systematic Review: Interventions for minimal change disease in adults with nephrotic syndrome.
4 Mar, 2022 | 08:47h | UTCInterventions for minimal change disease in adults with nephrotic syndrome – Cochrane Library
Commentary: Interventions for minimal change disease in adults with nephrotic syndrome – Cochrane Library
Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts.
4 Mar, 2022 | 08:45h | UTCCommentaries:
Living a long life is a multi-step process – The Lancet Public Health
Cohort Study: Mental health outcomes in transgender and nonbinary youths receiving gender-affirming care.
4 Mar, 2022 | 08:43h | UTCInvited Commentary: A Multipronged, Evidence-Based Approach to Improving Mental Health Among Transgender and Gender-Diverse Youth – JAMA Network Open
Podcast: Obesity medicine pearls.
4 Mar, 2022 | 08:43h | UTC#324: Obesity Medicine FAQ with Dr. Fatima Cody Stanford – The Curbsiders
JAMA Guide to Statistics and Methods: Causal Directed Acyclic Graphs.
4 Mar, 2022 | 08:40h | UTCCausal Directed Acyclic Graphs – JAMA (free for a limited period)
Review: Implementing machine learning in medicine.
4 Mar, 2022 | 08:42h | UTCImplementing machine learning in medicine – Canadian Medical Association Journal
Related:
Primer for artificial intelligence in primary care.
A Clinician’s Guide to Artificial Intelligence: How to Critically Appraise Machine Learning Studies
Review | AI and the cardiologist: when mind, heart and machine unite.
Review: Artificial intelligence in health and medicine.
Opinion | AI-facilitated health care requires education of clinicians
Welcoming new guidelines for AI clinical research
Diagnosis, management and therapeutic strategies for congenital long QT syndrome.
4 Mar, 2022 | 08:39h | UTCDiagnosis, management and therapeutic strategies for congenital long QT syndrome – Heart
Commentary on Twitter
Excellent review on congential long QT syndrome:
Diagnosis, management and therapeutic strategies for congenital long QT syndromehttps://t.co/FECINw9k7g pic.twitter.com/O4s5GwKK3O
— Heart_BMJ (@Heart_BMJ) June 19, 2021
Renal compression in heart failure: the renal tamponade hypothesis.
4 Mar, 2022 | 08:36h | UTCRenal Compression in Heart Failure: The Renal Tamponade Hypothesis – JACC: Heart Failure
Summary: Review of Renal Compression in Heart Failure: Key Points – American College of Cardiology