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Daily Archives: January 20, 2022

Booster longevity: Data reveals how long a third shot protects.

20 Jan, 2022 | 09:33h | UTC

Booster longevity: Data reveals how long a third shot protects – NPR

Original Report: SARS-CoV-2 variants of concern and variants under investigation in England – U.K. Health Security Agency

 


A populational-based retrospective cohort study in Qatar showed a reduced risk of Covid-19 breakthrough infections with the Moderna vs. the Pfizer–BioNTech vaccine.

20 Jan, 2022 | 09:30h | UTC

Effectiveness of mRNA-1273 and BNT162b2 Vaccines in Qatar – New England Journal of Medicine

 

Commentary on Twitter

 


Heart function recovered quickly in children with COVID-19-related multisystem inflammatory syndrome (MIS-C).

20 Jan, 2022 | 09:26h | UTC

News Release: Heart function recovered quickly in children with COVID-19-related MIS-C condition – American Heart Association

Original Study: Longitudinal Assessment of Cardiac Outcomes of Multisystem Inflammatory Syndrome in Children Associated With COVID‐19 Infections – Journal of the American Heart Association

 


Short Review: Fluvoxamine for symptomatic outpatients with COVID-19.

20 Jan, 2022 | 09:25h | UTC

Fluvoxamine for symptomatic outpatients with COVID-19 – Canadian Medical Association Journal

Related:

Fluvoxamine for Covid-19: What Prescribers and Pharmacists Need to Know.

Fluvoxamine for the early treatment of SARS-CoV-2 Infection: a review of current evidence.

RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19.

[Preprint] RCT: Fluvoxamine reduced the risk for ER visits and hospitalization among patients with Covid-19.

Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine).

Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19

 


Milder disease with Omicron: is it the virus or the pre-existing immunity?

20 Jan, 2022 | 09:28h | UTC

Milder disease with Omicron: is it the virus or the pre-existing immunity? – Nature Reviews Immunology

 


How does Omicron spread so fast? A high viral load isn’t the answer – “Data on viral levels point to immune evasion as a cause of the variant’s transmissibility”.

20 Jan, 2022 | 09:27h | UTC

How does Omicron spread so fast? A high viral load isn’t the answer – Nature

 


A large observational study showed people with immune disfunction (HIV, solid organ transplant, rheumatoid arthritis) were at increased risk of breakthrough Covid-19 infection after vaccination.

20 Jan, 2022 | 09:24h | UTC

Association Between Immune Dysfunction and COVID-19 Breakthrough Infection After SARS-CoV-2 Vaccination in the US – JAMA Internal Medicine

 


Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.

20 Jan, 2022 | 09:17h | UTC

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis – The Lancet

News Release: An estimated 1.2 million people died in 2019 from antibiotic-resistant bacterial infections, more deaths than HIV/AIDS or malaria – The Lancet

Editorial: Antimicrobial resistance: time to repurpose the Global Fund – The Lancet

Commentary: Antimicrobial resistance now a leading cause of death worldwide, study finds – The Guardian

 

Commentary on Twitter

 


10 lessons I’ve learned from the Covid–19 pandemic.

20 Jan, 2022 | 09:21h | UTC

10 lessons I’ve learned from the Covid–19 pandemic – STAT

 


Covid pandemic ‘nowhere near over,’ WHO says.

20 Jan, 2022 | 09:18h | UTC

Covid pandemic ‘nowhere near over,’ WHO says – CNN

 


After Omicron, we could use a break. We may just get it.

20 Jan, 2022 | 09:21h | UTC

After Omicron, we could use a break. We may just get it – STAT

 


RCT: Among patients with recurrent Clostridioides difficile infection, the use of SER-109, an oral microbiome therapy, reduced recurrence rate compared to placebo (12% vs. 40%).

20 Jan, 2022 | 09:11h | UTC

SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection – New England Journal of Medicine (link to abstract – $ for full-text)

 


1.8 million excess deaths attributable to urban air pollution in 2019, modelling study suggests.

20 Jan, 2022 | 09:13h | UTC

News Release: The Lancet Planetary Health: 1.8 million excess deaths attributable to urban air pollution in 2019, modelling study suggests

Original Study: Global urban temporal trends in fine particulate matter (PM2·5) and attributable health burdens: estimates from global datasets – The Lancet Planetary Health

Related Studies:

Internalising health-economic impacts of air pollution into climate policy: a global modelling study – The Lancet Planetary Health

Long-term trends in urban NO2 concentrations and associated paediatric asthma incidence: estimates from global datasets – The Lancet Planetary Health

 

Commentary on Twitter (thread – click for more)

 


RCT: In very young children with Type 1 Diabetes, a hybrid closed-loop therapy (“artificial pancreas”) resulted in better glycemic control without increased risk of hypoglycemia vs. sensor-augmented pump therapy.

20 Jan, 2022 | 09:07h | UTC

Randomized Trial of Closed-Loop Control in Very Young Children with Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Artificial pancreas proves ‘life-changing’ for very young children with type 1 diabetes and their families – University of Cambridge

 


M-A: the accuracy of serological tests to support the diagnosis of celiac disease.

20 Jan, 2022 | 09:02h | UTC

Systematic review with meta-analysis: the accuracy of serological tests to support the diagnosis of coeliac disease – Alimentary Pharmacology & Therapeutics

 


Meta-analysis of randomized controlled trials: Drug treatment for panic disorder with or without agoraphobia.

20 Jan, 2022 | 09:06h | UTC

Drug treatment for panic disorder with or without agoraphobia: systematic review and network meta-analysis of randomised controlled trials – The BMJ

 


Study shows that the retinal age gap might be a potential biomarker of aging linked to increased mortality risk.

20 Jan, 2022 | 09:04h | UTC

Retinal age gap as a predictive biomarker for mortality risk – British Journal of Ophthalmology (link to abstract – $ for full-text)

News Release: Difference between retina’s biological age and person’s real age linked to heightened death risk – BMJ

 

Commentary on Twitter

 


Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: ASCO-OH (CCO) Guideline Update.

20 Jan, 2022 | 08:57h | UTC

Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: ASCO-OH (CCO) Guideline Update – Journal of Clinical Oncology

 

Commentary on Twitter

 


Systematic Review: Prevalence, incidence and survival of heart failure.

20 Jan, 2022 | 09:00h | UTC

Prevalence, incidence and survival of heart failure: a systematic review – Heart

 


O-RADS MRI Risk Stratification System: Guide for Assessing Adnexal Lesions from the ACR O-RADS Committee.

20 Jan, 2022 | 08:59h | UTC

O-RADS MRI Risk Stratification System: Guide for Assessing Adnexal Lesions from the ACR O-RADS Committee – Radiology

 


Consensus recommendations on managing the selected comorbidities including cardiovascular disease, osteoporosis, and interstitial lung disease in rheumatoid arthritis.

20 Jan, 2022 | 08:52h | UTC

Consensus recommendations on managing the selected comorbidities including cardiovascular disease, osteoporosis, and interstitial lung disease in rheumatoid arthritis – Medicine

 


Review: Evaluating the patient with a pulmonary nodule.

20 Jan, 2022 | 08:56h | UTC

Evaluating the Patient With a Pulmonary Nodule: A Review – JAMA (free for a limited period)

Author Interview: Evaluation and Management of Patients With Pulmonary Nodules

 


Consensus Statement: Exercise/physical activity in individuals with Type 2 Diabetes.

20 Jan, 2022 | 08:51h | UTC

Exercise/Physical Activity in Individuals with Type 2 Diabetes: A Consensus Statement from the American College of Sports Medicine – Medicine & Science in Sports & Exercise

 

Commentary from the author on Twitter

 


Review: Diagnosis and treatment of polycystic ovary syndrome.

20 Jan, 2022 | 08:54h | UTC

Diagnosis and Treatment of Polycystic Ovary Syndrome – JAMA (free for a limited period)

 


How do we make decisions for the most immature babies, with their families?

20 Jan, 2022 | 08:49h | UTC

How do we make decisions for the most immature babies, with their families? – Neonatal Research

 


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