Daily Archives: December 16, 2021 | LinksMedicus Free Medical News & Perspectives

Review uncovers weak COVID clinical practice guidelines.

16 Dec, 2021 | 10:31h | UTC

Review uncovers weak COVID clinical practice guidelines – CIDRAP

Original Study: Adherence of Clinical Practice Guidelines for Pharmacologic Treatments of Hospitalized Patients With COVID-19 to Trustworthy Standards: A Systematic Review – JAMA Network Open

Commentary on Twitter

This systematic review found that few clinical practice guidelines for pharmacologic treatment of hospitalized patients with #COVID19 met the National Academy of Medicine standards for trustworthy guidelines. https://t.co/nOCDp4pJWx

— JAMA Network Open (@JAMANetworkOpen) December 10, 2021

Modeling COVID-19 mortality across 44 Countries: Face covering may reduce deaths.

16 Dec, 2021 | 10:33h | UTC

Modeling COVID-19 Mortality Across 44 Countries: Face Covering May Reduce Deaths – American Journal of Preventive Medicine

Commentary: Mask laws could prevent unnecessary COVID-19 deaths, study shows – News Medical

Autoimmune encephalitis after SARS-CoV-2 infection: case frequency, findings, and outcomes.

16 Dec, 2021 | 09:47h | UTC

Autoimmune Encephalitis After SARS-CoV-2 Infection: Case Frequency, Findings, and Outcomes – Neurology

Commentary on Twitter

Autoimmune Encephalitis After SARS-CoV-2 Infection: Case Frequency, Findings, and Outcomes https://t.co/KIKzlf3hev #COVID #Neurology pic.twitter.com/q2Qf7NeJHo

— Neurology Journal (@GreenJournal) December 11, 2021

Merck’s COVID pill loses its luster: what that means for the pandemic – “Molnupiravir was initially heralded by public-health officials as a game-changer for COVID-19, but full clinical-trial data showed lower-than-expected efficacy”.

16 Dec, 2021 | 09:52h | UTC

Merck’s COVID pill loses its lustre: what that means for the pandemic – Nature

FDA panel narrowly recommends authorization of first antiviral pill to treat COVID.

[Press release – not published yet] Merck’s new Covid-19 pill Molnupiravir updated data shows reduced efficacy (30%) for preventing hospitalization and death compared to initial results (50%). Absolute risk reduction of hospitalization and death fell from 7% to 3%.

8 lingering questions about the new Covid pills from Merck and Pfizer.

COVID antiviral pills: what scientists still want to know – “Drugs like Molnupiravir and Paxlovid could change the course of the pandemic if clinical trial results hold up in the real world”.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

A prominent virologist warns new COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm.

The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.

Merck to allow other nations to produce new COVID-19 antiviral.

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.

Opinion: Unequal global vaccine coverage is at the heart of the current covid-19 crisis.

16 Dec, 2021 | 09:50h | UTC

Unequal global vaccine coverage is at the heart of the current covid-19 crisis – The BMJ

Management of Hip Fractures in Older Adults: Evidence-Based Clinical Practice Guideline.

16 Dec, 2021 | 09:42h | UTC

Management of Hip Fractures in Older Adults Evidence-Based Clinical Practice Guideline – American Academy of Orthopaedic Surgeons

Summary: Management of Hip Fractures in Older Adults – American Academy of Orthopaedic Surgeons

News Release: AAOS Updates Clinical Practice Guideline for Management of Hip Fractures in Older Adults

Recommendations for antibiotic selection for severe nosocomial infections.

16 Dec, 2021 | 09:40h | UTC

Recommendations for antibiotic selection for severe nosocomial infections – Revista Espanola de Quimioterapia

T Cells might be our bodies’ best shot against Omicron.

16 Dec, 2021 | 09:45h | UTC

T Cells Might Be Our Bodies’ Best Shot Against Omicron – The Atlantic

Sepsis in children: state-of-the-art treatment.

16 Dec, 2021 | 08:56h | UTC

Sepsis in children: state-of-the-art treatment – Therapeutic Advances in Infectious Disease

Abortion safety and use with normally prescribed Mifepristone in Canada.

16 Dec, 2021 | 08:51h | UTC

Abortion Safety and Use with Normally Prescribed Mifepristone in Canada – New England Journal of Medicine

News Release: Prescribing the abortion pill without restrictions is safe and effective, study finds – University of British Columbia

Antibiotics in critically ill children—a narrative review on different aspects of a rational approach.

16 Dec, 2021 | 08:53h | UTC

Antibiotics in critically ill children—a narrative review on different aspects of a rational approach – Pediatric Research

Phase 3 trials of Tapinarof cream for plaque psoriasis.

16 Dec, 2021 | 08:49h | UTC

Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis – New England Journal of Medicine

Commentary: Topical tapinarof reduces severity of plaque psoriasis – HealthDay

Commentary on Twitter

In two trials of treatment for psoriasis with the topical aryl hydrocarbon receptor–modulating agent tapinarof, clearance of lesions occurred in a larger proportion of patients who used tapinarof cream than of those who used placebo. https://t.co/I4zgVFELhz pic.twitter.com/qT6lbaJK0U

— NEJM (@NEJM) December 10, 2021