Daily Archives: December 9, 2021
Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech vaccine had 90% effectiveness at preventing death due to Covid-19 compared to a two-dose regimen.
9 Dec, 2021 | 10:35h | UTCBNT162b2 Vaccine Booster and Mortality Due to Covid-19 – New England Journal of Medicine
Editorial: Booster Doses and Prioritizing Lives Saved
[Press release – not published yet] Lab study suggests a third dose (booster) of the Pfizer–BioNTech vaccine may be necessary to provide an adequate immune response to the Omicron variant.
9 Dec, 2021 | 10:29h | UTCPress release: Pfizer and Biontech provide update on Omicron variant
Commentaries:
Omicron likely to weaken COVID vaccine protection – Nature
Pfizer-BioNTech says COVID booster should protect against Omicron – CIDRAP
Covid: Pfizer says booster shot promising against Omicron – BBC
Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech vaccine reduced the rates of confirmed Covid-19 and severe illness compared to a two-dose regimen.
9 Dec, 2021 | 10:32h | UTCProtection against Covid-19 by BNT162b2 Booster across Age Groups – New England Journal of Medicine
Editorial: Booster Doses and Prioritizing Lives Saved
As 57 countries report Omicron cases, Pfizer says its boosters offer protection – but WHO cautions more research is needed.
9 Dec, 2021 | 10:28h | UTCSee also: Covid: Vaccines should work against Omicron variant, WHO says – BBC
Multiple early studies find notable Omicron vaccine evasion.
9 Dec, 2021 | 10:26h | UTCMultiple early studies find notable Omicron vaccine evasion – CIDRAP
Related: A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants.
RCT: Among children between the ages of 6 and 11 years with uncontrolled moderate-to-severe asthma, add-on Dupilumab reduced exacerbations and improved lung function.
9 Dec, 2021 | 10:21h | UTCDupilumab in Children with Uncontrolled Moderate-to-Severe Asthma – New England Journal of Medicine
RCT: In critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful first attempt intubation vs. with use of an endotracheal tube with stylet.
9 Dec, 2021 | 10:22h | UTCEffect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial – JAMA (free for a limited period)
Related: Randomized Trial: Comparison of Intubation Techniques in Patients with Difficult Airways
Opinion: Why are we still isolating vaccinated people for 10 days?
9 Dec, 2021 | 10:24h | UTCWhy Are We Still Isolating Vaccinated People for 10 Days? – The Atlantic
Outcomes associated with caustic ingestion among 1198 adults in a national prospective database in France.
9 Dec, 2021 | 10:19h | UTCOutcomes Associated With Caustic Ingestion Among Adults in a National Prospective Database in France – JAMA Surgery (free for a limited period)
Invited commentary: Caustic Ingestion—The Haves and the Have Nots (free for a limited period)
Commentary on Twitter
Study provides nation-wide data regarding in-hospital patients' outcomes after caustic ingestion. Severity of ingestion and hospital volume are associated with mortality. If feasible, low volume hospitals should transfer patients to larger centers https://t.co/VbX1jhGbjJ
— JAMA Surgery (@JAMASurgery) December 8, 2021
M-A: Effects of immediate or early oral feeding on acute pancreatitis.
9 Dec, 2021 | 10:14h | UTC
Review: Current issues in the use of opioids for the management of postoperative pain.
9 Dec, 2021 | 10:18h | UTCCurrent Issues in the Use of Opioids for the Management of Postoperative Pain: A Review – JAMA Surgery (free for a limited period)
Recommended standards for the performance of transesophageal echocardiographic screening for structural heart intervention.
9 Dec, 2021 | 10:11h | UTC
Commentary on Twitter
New TEE in Structural Heart Intervention Guideline Now Available Online: https://t.co/BtqTHmSNHY
Lead author @hahn_rt will present 2 webinars on this guideline Dec. 15 & 17. Save the date. Registration will open soon! pic.twitter.com/GL9ndSini6— ASE (@ASE360) November 18, 2021
New Zealand to ban smoking for next generation in bid to outlaw habit by 2025 – “New legislation means the legal smoking age will increase every year, to create a smoke-free generation of New Zealanders”.
9 Dec, 2021 | 10:12h | UTCNew Zealand to ban smoking for next generation in bid to outlaw habit by 2025 – The Guardian
Systematic Review: Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer.
9 Dec, 2021 | 10:08h | UTC
Commentary on Twitter (thread – click for more)
Our comprehensive #systematicreview for the #ECIBC on intervals (every 1, 2, 3 years) of #breastcancer #screening is available.
We included RCT, observational, and mathematical modeling studies to assess benefits and harms and applied the #GRADE approachhttps://t.co/IfplsWfKuA pic.twitter.com/7niEbnaWKR— Carlos Canelo-Aybar (@ccaneloa) November 27, 2021
Update in the diagnosis and management of acute pulmonary embolism for the non-respiratory physician.
9 Dec, 2021 | 10:00h | UTC
Modern day management of a unilateral pleural effusion.
9 Dec, 2021 | 09:58h | UTCModern day management of a unilateral pleural effusion – Clinical Medicine Journal
Blood sugar targets in surgical intensive care: management and special considerations in patients with diabetes.
9 Dec, 2021 | 10:06h | UTCBlood Sugar Targets in Surgical Intensive Care – Deutsches Ärzteblatt International
Interstitial lung disease on the acute take for the non-respiratory physician.
9 Dec, 2021 | 09:57h | UTC
Review: Diagnosis and management of non-cystic fibrosis bronchiectasis.
9 Dec, 2021 | 09:53h | UTCDiagnosis and management of non-cystic fibrosis bronchiectasis – Clinical Medicine Journal
Review: Lung cancer for the non-respiratory physician.
9 Dec, 2021 | 09:54h | UTCLung cancer for the non-respiratory physician – Clinical Medicine Journal