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Daily Archives: December 1, 2021

Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic.

1 Dec, 2021 | 09:52h | UTC

Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic – Critical Care

 


WHO advice for international traffic in relation to the SARS-CoV-2 Omicron variant (B.1.1.529).

1 Dec, 2021 | 10:02h | UTC

WHO advice for international traffic in relation to the SARS-CoV-2 Omicron variant (B.1.1.529) – World Health Organization

Commentary: Over-60s, vulnerable should postpone travel due to Omicron: WHO – MedicalXpress

See also the latest articles on the subject:

Will omicron – the new coronavirus variant of concern – be more contagious than delta? A virus evolution expert explains what researchers know and what they don’t – The Conversation

WHO pleads for ‘rational’ Omicron response – MedicalXpress

Omicron: WHO warns of ‘high infection risk’ around globe – BBC

Video: Why Omicron is the most worrying Covid variant yet – video explainer – The Guardian

Doctors hope Omicron causes milder cases of Covid — but it’s still too early to say – STAT

Doctor: Many South Africans ill in surge have mild symptoms – Associated Press

New Findings Show the Omicron Variant Spread Widely At a Faster Pace Than Initially Thought – TIME

Why some researchers think the omicron variant could be the most infectious one yet – NPR

Omicron Covid variant ‘present in Europe at least 10 days ago’ – The Guardian

Netherlands says Omicron variant was already in country earlier than previously thought – CNN

Netherlands detections hint at earlier Omicron spread – CIDRAP

Epidemiologist awaits clearer picture on omicron – Harvard University

Pfizer research head envisions a sprint to develop Omicron vaccine, if it’s needed – STAT

Omicron COVID variant was in Europe before South African scientists detected and flagged it to the world – CBS News

Moderna boss predicts current vaccines may be less effective against Omicron – The Guardian

Wealthy nations starved the developing world of vaccines. Omicron shows the cost of this greed – The Conversation

Travel restrictions by country following the Omicron variant outbreak – CNN

 


FDA panel narrowly recommends authorization of first antiviral pill to treat COVID.

1 Dec, 2021 | 09:56h | UTC

FDA panel narrowly recommends authorization of first antiviral pill to treat COVID – STAT

See also: An FDA panel supports Merck COVID drug in mixed vote – NPR

Related:

[Press release – not published yet] Merck’s new Covid-19 pill Molnupiravir updated data shows reduced efficacy (30%) for preventing hospitalization and death compared to initial results (50%). Absolute risk reduction of hospitalization and death fell from 7% to 3%.

8 lingering questions about the new Covid pills from Merck and Pfizer.

COVID antiviral pills: what scientists still want to know – “Drugs like Molnupiravir and Paxlovid could change the course of the pandemic if clinical trial results hold up in the real world”.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

A prominent virologist warns new COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm.

The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.

Merck to allow other nations to produce new COVID-19 antiviral.

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.

 


Ending the COVID-19 Pandemic Hinges on Trust: Science alone won’t pull us out of the pandemic.

1 Dec, 2021 | 09:47h | UTC

Ending the COVID-19 Pandemic Hinges on Trust – Think Global Health

 

Commentary on Twitter

 


Using wearable data, a real-time alerting system can be used for the early detection of Covid-19 and other stress events.

1 Dec, 2021 | 09:59h | UTC

Real-time alerting system for COVID-19 and other stress events using wearable data – Nature Medicine

Commentary: Scientists develop a smartwatch-based device for early detection of COVID-19 – News Medical

 

Commentary on Twitter

 


Another randomized trial showed convalescent plasma does not benefit patients hospitalized with Covid-19.

1 Dec, 2021 | 09:49h | UTC

Effect of High-Titer Convalescent Plasma on Progression to Severe Respiratory Failure or Death in Hospitalized Patients With COVID-19 Pneumonia: A Randomized Clinical Trial – JAMA Network Open

Related:

M-A: Convalescent plasma does not reduce mortality in COVID-19.

RCT: Another study shows convalescent plasma does not improve outcomes in critically ill patients with Covid-19.

RCT: Convalescent plasma does not improve outcomes and may be harmful to hospitalized patients with COVID-19.

NIH study shows no significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms.

M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.

RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.

 

Commentary on Twitter

 


Guidelines developed under pressure. The case of the COVID-19 low-quality “rapid” guidelines and potential solutions.

1 Dec, 2021 | 08:54h | UTC

Guidelines developed under pressure. The case of the COVID-19 low-quality “rapid” guidelines and potential solutions – Journal of Clinical Epidemiology

 


Cohort study: Allergic conditions linked to lower COVID-19 infection risk.

1 Dec, 2021 | 08:52h | UTC

News Release: Allergic conditions linked to lower COVID-19 infection risk – BMJ

Original Study: Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) – Thorax

 


NICE Guideline | Tobacco: preventing uptake, promoting quitting, and treating dependence.

1 Dec, 2021 | 08:50h | UTC

Tobacco: preventing uptake, promoting quitting and treating dependence – National Institute for Health and Care Excellence

 


RCT: Intravenous or intraosseous calcium does not improve the return of spontaneous circulation in adults with out-of-hospital cardiac arrest.

1 Dec, 2021 | 08:46h | UTC

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial – JAMA

 

Commentary on Twitter

 


AAP Clinical Report: Promoting the participation of children and adolescents with disabilities in sports, recreation, and physical activity.

1 Dec, 2021 | 08:48h | UTC

Promoting the Participation of Children and Adolescents With Disabilities in Sports, Recreation, and Physical Activity – Pediatrics

 

Commentary on Twitter

 


M-A: Efficacy of non-invasive and invasive respiratory management strategies in adult patients with acute hypoxemic respiratory failure.

1 Dec, 2021 | 08:44h | UTC

Efficacy of non-invasive and invasive respiratory management strategies in adult patients with acute hypoxaemic respiratory failure: a systematic review and network meta-analysis – Critical Care

 


Global estimates of viral suppression in 31 countries shows too many people with HIV fail to achieve durable viral suppression.

1 Dec, 2021 | 08:41h | UTC

News Release: Too many people with HIV fail to achieve durable viral suppression – NIH News Releases

Original Study: Global estimates of viral suppression in children and adolescents and adults on antiretroviral therapy adjusted for missing viral load measurements: a multiregional, retrospective cohort study in 31 countries – The Lancet HIV (link to abstract – $ for full-text)

 


Review: Ethical advice in pediatric care.

1 Dec, 2021 | 08:42h | UTC

Ethical advice in paediatric care – Archives of Disease in Childhood

 


Integrative oncology: Addressing the global challenges of cancer prevention and treatment.

1 Dec, 2021 | 08:34h | UTC

Integrative oncology: Addressing the global challenges of cancer prevention and treatment – Ca: A Cancer Journal for Clinicians

Commentary: Addressing the Global Challenges of Cancer Prevention and Treatment – The ASCO Post

 


Review: Current treatment and future directions in the management of anal cancer.

1 Dec, 2021 | 08:38h | UTC

Current treatment and future directions in the management of anal cancer – CA: A Cancer Journal for Clinicians

 


Systematic Review: Late (after 6 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.

1 Dec, 2021 | 08:32h | UTC

Late (≥ 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants – Cochrane Library

 


CT imaging of peritoneal carcinomatosis with surgical correlation: a pictorial review.

1 Dec, 2021 | 08:30h | UTC

CT imaging of peritoneal carcinomatosis with surgical correlation: a pictorial review – Insights into Imaging

 


Systematic Review: Early (started within six days) systemic postnatal corticosteroids for preventing bronchopulmonary dysplasia in preterm infants.

1 Dec, 2021 | 08:33h | UTC

Summary: Early (started within six days) systemic postnatal corticosteroids for preventing bronchopulmonary dysplasia in preterm infants – Cochrane Library

Original Study: Early (< 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants – Cochrane Library

 

Commentary on Twitter

 


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