Daily Archives: November 18, 2021
M-A: Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality.
18 Nov, 2021 | 08:59h | UTC
Commentary on Twitter
Experts call for continued use of personal protective and social measures alongside covid-19 vaccination in @bmj_latest today https://t.co/MOT4O2R6Ui pic.twitter.com/dAxhStSxpJ
— BMJ (@bmj_company) November 18, 2021
Review: Should children under 12 years of age be vaccinated against COVID-19?
18 Nov, 2021 | 08:56h | UTCShould children be vaccinated against COVID-19? – Archives of Disease in Childhood
Commentary from the author on Twitter (thread – click for more)
Should #children be vaccinated against #COVID19?
Our review outlines the points to consider in weighing up whether all healthy children under 12y should be vaccinated against COVID-19.https://t.co/JtoOr2TZoq#medpeds #IDTwitter #PaedsID #tweetiatrician #paediatrics
?1/n pic.twitter.com/g4UGu3pMsE
— Nigel Curtis (@nigeltwitt) November 6, 2021
Covid: Children in UK told to delay jab for 12 weeks after infection.
18 Nov, 2021 | 08:54h | UTCCovid: Children told to delay jab for 12 weeks after infection – BBC
Original Report: Joint Committee on Vaccination and Immunisation (JCVI) advice on COVID-19 vaccination in people aged 16 to 17 years: 15 November 2021
Observational study finds mRNA vaccination is associated with an effectiveness of 85% against Covid-19 hospitalization.
18 Nov, 2021 | 08:49h | UTCAssociation Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity – JAMA
Editorial: Understanding Breakthrough Infections Following mRNA SARS-CoV-2 Vaccination – JAMA
Commentary: COVID-19 vaccines 85% effective against hospital cases but weaken over time – TCTMD
Related Study: Study compares the decline in effectiveness for Moderna, Pfizer, and Janssen vaccines and consequences for mortality.
[Preprint] M-A: Inhaled corticosteroids in COVID-19 outpatients.
18 Nov, 2021 | 08:48h | UTCInhaled Corticosteroids for Outpatients with Covid-19: A Meta-Analysis – medRxiv
Commentary: Favourable meta-analysis of inhaled corticosteroids in COVID-19 outpatients – News Medical
Related:
Position Paper: Recommendations for the use of topical inhalant budesonide in COVID-19.
RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19
Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19
Commentary on Twitter
The first meta-analysis of the 4 completed & reported trials of outpatient inhaled corticosteroid #COVID19 treatment
The results support the use of inhaled corticosteroids (ciclesonide or budesonide) for the resolution of symptoms at day 14 of treatmenthttps://t.co/KnBDKhfYmi pic.twitter.com/WSd9htXwe4— Antibiotic Stewa®️x? Bassam Ghanem (@ABsteward) November 5, 2021
Observational study finds the effectiveness of mRNA vaccination against Covid-19 hospitalization was lower (77%) among immunocompromised adults than among immunocompetent adults (90%).
18 Nov, 2021 | 08:52h | UTCRelated:
CDC Guidance: Immunocompromised may need a fourth Covid-19 shot.
Commentary on Twitter (thread – click for more)
New CDC study of mRNA #vaccination & disease in 89,000 ppl hospitalized w/#COVID19
– 69K had normal immune systems; 1/2 of them were 2-dose vaxed
– 20K had systs weakened by cancer or other illnesses, 25% of whom were unvaxed
– Vax was 90% effective in preventing severe…
MORE pic.twitter.com/w3RFCrQnLB— Laurie Garrett (@Laurie_Garrett) November 2, 2021
8 lingering questions about the new Covid pills from Merck and Pfizer.
18 Nov, 2021 | 08:46h | UTC8 lingering questions about the new Covid pills from Merck and Pfizer – STAT
Related:
The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.
Merck to allow other nations to produce new COVID-19 antiviral.
Video: Merck’s Covid pill could transform treatment. Here’s how it works.
How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.
What we know — and don’t know — about Merck’s new Covid-19 pill.
Merck’s Covid-19 pill is great news but may not be a game-changer.
Video | A Pill For COVID? A Doctor Explains Molnupiravir.
Observational study in patients with stroke with large-vessel occlusion presenting in the extended window suggests non-contrast CT is as good as CT perfusion or MRI to select patients for thrombectomy.
18 Nov, 2021 | 08:41h | UTCCommentary: Noncontrast CT a cost-friendly alternative to select late-stroke patients for thrombectomy – Health Imaging
Commentary on Twitter
Don’t have CTP worry not! No MRI/MRP worry not! Good old non-contrast CTH performs just as well for pt selection! But I do like those colored CBF, CBV, MTT maps & don’t like the errors in image processing! This will inc access to late thrombectomy #NoELVOleftbehind @almuftifawaz https://t.co/vBv5y2IDjT
— Neha Dangayach MD MSCR FNCS (@drdangayach) November 11, 2021
NICE Guideline | Heart valve disease presenting in adults: investigation and management.
18 Nov, 2021 | 08:44h | UTCRelated Guidelines:
2020 ACC/AHA Guideline for the management of patients with valvular heart disease
RCT: An exercise program reduced upper limb disability one year after non-reconstructive breast cancer surgery.
18 Nov, 2021 | 08:39h | UTCCommentaries:
Exercise reduces upper limb disability after breast cancer surgery – BMJ / News Medical
Exercise Helps Ease Arm, Shoulder Pain After Breast Cancer Surgery- HealthDay
Structured Exercise Improves Upper Limb Function After Breast Ca Surgery – Physician’s Weekly
Commentary on Twitter
Women who exercise shortly after having non-reconstructive breast cancer surgery appear to regain better shoulder and arm mobility and experience less pain than those who receive standard care, finds this study @jxbruce https://t.co/BhIKb8RRjV
— The BMJ (@bmj_latest) November 11, 2021
M-A: In patients with anterior circulation acute stroke and evidence of reversible cerebral ischemia across the 6–24 h time window, thrombectomy was associated with higher rates of independence in activities of daily living at 90 days than best medical therapy alone.
18 Nov, 2021 | 08:43h | UTCThrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis – The Lancet (link to abstract – $ for full-text)
Editorial: Twenty recommendations to individualize interventions in the early resuscitation of patients with sepsis.
18 Nov, 2021 | 08:38h | UTCRelated: Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.
Review: A fresh look at coronary microembolization.
18 Nov, 2021 | 08:35h | UTCA fresh look at coronary microembolization – Nature Reviews Cardiology (if this link is paywalled, try this one)
Commentary on Twitter
In our latest Review, @PKleinbongard and Gerd Heusch take a fresh look at coronary microembolization and how it can be prevented and treated https://t.co/OLlcfGO6Ui pic.twitter.com/U5Qlg6Blqd
— Nature Reviews Cardiology (@NatRevCardiol) November 17, 2021
Demystifying the EEG report for intensivists.
18 Nov, 2021 | 08:36h | UTCDemystifying the EEG Report – NeuroEMCrit
Podcast | Liver emergencies: acute liver failure, hepatic encephalopathy, hepatorenal syndrome, liver test interpretation & drugs to avoid.
18 Nov, 2021 | 08:32h | UTCLiver Emergencies: Acute Liver Failure, Hepatic Encephalopathy, Hepatorenal Syndrome, Liver Test Interpretation & Drugs to Avoid – Emergency Medicines Cases (text summary and podcast)
What Is the best maintenance therapy for ANCA vasculitis?
18 Nov, 2021 | 08:34h | UTC
RCT: In Infants with infantile hemangioma, nadolol is noninferior to propranolol and may be an efficacious and safe alternative in cases of propranolol unresponsiveness or adverse events.
18 Nov, 2021 | 08:29h | UTCCommentary: Oral Nadolol Feasible for the Treatment of Infantile Hemangiomas – HealthDay
Commentary on Twitter
A randomized clinical trial found #nadolol is non-inferior to #propranolol in patients with infantile hemangioma—a safe and efficacious alternative when fast response is needed https://t.co/ECVFfFPBJ2
— JAMA Pediatrics (@JAMAPediatrics) November 9, 2021
New ACR radiation diagnostic reference levels for top 10 pediatric CT exams.
18 Nov, 2021 | 08:31h | UTCNews Release: New Radiation Diagnostic Reference Levels for Top 10 Pediatric CT Exams – American College of Radiology
Original Guideline: U.S. Diagnostic Reference Levels and Achievable Doses for 10 Pediatric CT Examinations – Radiology
Commentary: ACR releases new benchmarks to help radiology departments optimize radiation dose levels – Health Imaging
Systematic Review: Multidisciplinary rehabilitation for older people with hip fractures.
18 Nov, 2021 | 08:28h | UTCOriginal Study: Multidisciplinary rehabilitation for older people with hip fractures – Cochrane Library
Commentary on Twitter
JUST PUBLISHED – Multidisciplinary #rehabilitation for older people with hip fractures ➡️ https://t.co/kjhycTCjE8 Updated @CochraneBJMT systematic review looks at the evidence from 28 trials involving 5,351. @CochraneRehab @CCGlobalAgeing #rehab pic.twitter.com/ZamV4xHObh
— The Cochrane Library (@CochraneLibrary) November 12, 2021