Daily Archives: October 27, 2021
Breakthrough infections occur in those with lower antibody levels.
27 Oct, 2021 | 01:45h | UTCOriginal study: Covid-19 Breakthrough Infections in Vaccinated Health Care Workers – New England Journal of Medicine
FDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children ages 5 to 11.
27 Oct, 2021 | 01:48h | UTCFDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children – STAT
See also:
Tracking the FDA advisory panel meeting on Covid-19 vaccines for kids – STAT
FDA advisory panel recommends Pfizer vaccine for kids ages 5 to 11 – NPR
Mix-and-match COVID vaccines ace the effectiveness test – “No need for brand loyalty”.
27 Oct, 2021 | 01:42h | UTCMix-and-match COVID vaccines ace the effectiveness test – Nature
Related:
Should You Mix and Match Your Booster Shot?
A primer on what we know about mixing and matching Covid vaccines.
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.
RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.
Heterologous AstraZeneca/Pfizer vaccination seems to be associated with increased effectiveness against Covid-19 compared to homologous Pfizer/Pfizer vaccination.
27 Oct, 2021 | 01:44h | UTCImmunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination – Nature
Related:
Should You Mix and Match Your Booster Shot?
A primer on what we know about mixing and matching Covid vaccines.
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.
RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.
Commentary on Twitter
A dose of the AstraZeneca COVID-19 vaccine followed by a dose of the Pfizer/BioNTech vaccine confers better protection against SARS-CoV-2 infection than two doses of the Pfizer vaccine, according to a study in healthcare workers published in @Nature. https://t.co/6hIVkiOLQ1 pic.twitter.com/AmsyVUMpoj
— Nature Portfolio (@NaturePortfolio) October 26, 2021
What game theory can teach us about controlling pandemics.
27 Oct, 2021 | 01:39h | UTCWhat game theory can teach us about controlling pandemics – The BMJ Opinion
Commentary on Twitter
Sorry but panvax is just covax with money and better/early contracts – What game theory can teach us about controlling pandemics – The BMJ https://t.co/bZyhfxCkP3
— Amanda Glassman (@glassmanamanda) October 22, 2021
COVID super-immunity: one of the pandemic’s great puzzles – “People who have previously recovered from COVID-19 have a stronger immune response after being vaccinated than those who have never been infected. Scientists are trying to find out why”.
27 Oct, 2021 | 01:41h | UTCCOVID super-immunity: one of the pandemic’s great puzzles – Nature
AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract.
27 Oct, 2021 | 01:35h | UTC
Bioethics | The suggestion Covid deniers should stay out of Australian public hospitals is appalling.
27 Oct, 2021 | 01:37h | UTC
UEG Consensus on Functional Dyspepsia.
27 Oct, 2021 | 01:32h | UTC
RCT: Elective internal mammary node irradiation does not increase disease-free survival or overall survival in most women with node-positive breast cancer.
27 Oct, 2021 | 01:28h | UTCEffect of Elective Internal Mammary Node Irradiation on Disease-Free Survival in Women With Node-Positive Breast Cancer: A Randomized Phase 3 Clinical Trial – JAMA Oncology (free for a limited period)
Commentary: No Survival Benefit for Internal Mammary Node Irradiation in Breast Cancer — Women with medially or centrally located tumors may be candidates, however, says researcher – MedPage Today (free registration required)
Commentary on Twitter
Phase III randomized study evaluated the role of internal mammary node irradiation (IMNI) in node-positive #breastcancer. IMNI did not improve the DFS in unselected patients, but did improve DFS in patients with medially or centrally located tumors https://t.co/tw4ZrHn5wn pic.twitter.com/34ye3TR9MA
— JAMA Oncology (@JAMAOnc) October 25, 2021
Opinion | We Need to Ground Truth Assumptions about Gene Therapy – “Researchers, practitioners and patients must balance the discipline’s promise with its reality”.
27 Oct, 2021 | 01:21h | UTCWe Need to Ground Truth Assumptions about Gene Therapy – Nature
RCT: Platelet-rich intra-articular plasma injections do not improve symptoms and function in patients with ankle osteoarthritis.
27 Oct, 2021 | 01:26h | UTCEffect of Platelet-Rich Plasma Injections vs Placebo on Ankle Symptoms and Function in Patients With Ankle Osteoarthritis: A Randomized Clinical Trial – JAMA (free for a limited period)
Related:
RCT: In critically ill patients, an individualized glucose control targeting an ICU patient’s pre-admission usual glycemia did not demonstrate a survival benefit compared to conventional glucose control (targeting glycemia below 180 mg/dL).
27 Oct, 2021 | 01:17h | UTC
Anticoagulants and diabetes agents are among the most frequent causes of emergency department visits attributed to medication harms.
27 Oct, 2021 | 01:15h | UTCUS Emergency Department Visits Attributed to Medication Harms, 2017-2019 – JAMA (link to abstract – $ for full-text)
Commentaries:
Number of emergency room visits for medication harms increases with age – MedicalResearch.com
Blood thinners, diabetes meds among top causes of drug-related ER visits – UPI
RCT: Ozanimod as induction and maintenance therapy for ulcerative colitis.
27 Oct, 2021 | 01:19h | UTC
Commentary on Twitter
Visual Abstract: Ozanimod Therapy for Ulcerative Colitis https://t.co/P3XpOvV49P pic.twitter.com/ubqgQX94uW
— NEJM (@NEJM) October 6, 2021
M-A: The efficacy of pharmacotherapies for the treatment of borderline personality disorder is limited.
27 Oct, 2021 | 01:11h | UTC
Podcast: Atopic Dermatitis Pearls.
27 Oct, 2021 | 01:01h | UTCAtopic Dermatitis Pearls – The Cribsiders
Systematic Review: Virtual care in patients with cancer.
27 Oct, 2021 | 01:04h | UTCVirtual Care in Patients with Cancer: A Systematic Review – Current Oncology