Daily Archives: October 21, 2021
An analysis of Scotland’s mortality in 114,000 SARS-CoV2–infected people revealed that the vaccine effectiveness against death from the Delta variant was 90% for the Pfizer vaccine and 91% for AstraZeneca.
21 Oct, 2021 | 10:15h | UTC
Pfizer vaccine showed estimated effectiveness of 93% against symptomatic SARS-CoV-2 Delta variant infection in adolescents.
21 Oct, 2021 | 10:17h | UTC
Commentary on Twitter
The remarkably high effectiveness (VE) of vaccination for teens vs the Delta variant in over 94,000 vaccinees and 94,000 matched controls: 93% VE vs symptomatic infection (95% CI 88,97) https://t.co/wwoXlw7PH9@NEJM pic.twitter.com/8m3fJ7avc5
— Eric Topol (@EricTopol) October 20, 2021
A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.
21 Oct, 2021 | 10:14h | UTCRelated:
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
FDA authorizes booster doses of Moderna and Johnson & Johnson vaccines, says mix and match OK.
21 Oct, 2021 | 10:09h | UTCFDA authorizes booster doses of Moderna and Johnson & Johnson vaccines, says mix and match OK – CNN
See also:
FDA OKs mixing COVID vaccines; backs Moderna, J&J boosters – Associated Press
FDA OKs Moderna, J&J boosters, along with ‘mix and match’ approach – NBC News
NCCN Guideline: Cancer-Associated Venous Thromboembolic Disease.
21 Oct, 2021 | 10:06h | UTCRelated:
ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer
Review: venous and arterial thromboembolism in patients with cancer.
COVID-19 pneumonia: pathophysiology and management.
21 Oct, 2021 | 10:12h | UTCCOVID-19 pneumonia: pathophysiology and management – European Respiratory Review
Instead of quarantine for Covid-exposed students, some schools are trying test-to-stay.
21 Oct, 2021 | 10:08h | UTCInstead of quarantine for Covid-exposed students, some schools are trying test-to-stay – CNN
Related:
Opinion | Data from routine Covid testing can help schools stay open this year.
Guideline: Erectile Dysfunction.
21 Oct, 2021 | 10:01h | UTC
State of the Art Review: Diagnosis and management of bronchopulmonary dysplasia.
21 Oct, 2021 | 09:56h | UTCDiagnosis and management of bronchopulmonary dysplasia – The BMJ
Commentary on Twitter
This new clinical review evaluates the various clinical definitions, imaging modalities, and biomarker data that are helpful in making an early diagnosis of bronchopulmonary dysplasia (BPD), as well as the evidence on the prevention and treatment of BPD https://t.co/ITqe8WMkNl
— The BMJ (@bmj_latest) October 20, 2021
Opinion | Understanding of research results, evidence summaries and their applicability—not critical appraisal—are core skills of medical curriculum.
21 Oct, 2021 | 09:57h | UTC
Commentary on Twitter
Is the critical appraisal of individual studies a core skill for clinicians? @KariTikkinen and @EBCPMcMaster argue that there are more important things for them to learn in order to apply #EBM in real life.
A thought-provoking piece in @BMJ_EBM ?https://t.co/f6KvsRpHOw pic.twitter.com/FOf5ywT1bf
— Lucas Morin (@lucasmorin_eolc) October 20, 2021
Five-year follow-up of RCT: Arthroscopic subacromial decompression provided no benefit over diagnostic arthroscopy or exercise therapy on return to work in patients with shoulder impingement syndrome.
21 Oct, 2021 | 09:54h | UTCRelated:
Randomized Trial: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement
Research: Arthroscopic subacromial decompression for subacromial shoulder pain
Systematic Review: Subacromial Decompression Surgery for Rotator Cuff Disease
Systematic Review: Surgery for Rotator Cuff Tears
The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.
21 Oct, 2021 | 09:48h | UTC
In a major scientific advance, a pig kidney is successfully transplanted into a human.
21 Oct, 2021 | 09:52h | UTCIn a major scientific advance, a pig kidney is successfully transplanted into a human – NPR
Opinion | Is it time for Evidence-Based Medicine 2.0?
21 Oct, 2021 | 09:59h | UTCIs it time for Evidence-Based Medicine 2.0? – Centre for Evidence-Based Medicine
ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer.
21 Oct, 2021 | 09:48h | UTCPress release: metastatic breast cancer: new ESMO guideline with evidence-based recommendations – European Society of Medical Oncology
Cohort Study: Hypertensive disorders of pregnancy are associated with a 6-fold or higher increased risk of chronic hypertension in the first years following delivery.
21 Oct, 2021 | 09:51h | UTCEditorial: Impact of hypertensive disorders of pregnancy: lessons from CONCEPTION
Commentary on Twitter
Hypertensive disorders of pregnancy and onset of chronic hypertension in France: the nationwide CONCEPTION study@escardio #EHJ #cardiotwitterhttps://t.co/OnJRP94W6v pic.twitter.com/N3dLNTD5XU
— EHJ Editor-in-Chief (@ehj_ed) October 17, 2021
RCT: Nivolumab vs. placebo in patients with relapsed malignant mesothelioma.
21 Oct, 2021 | 09:46h | UTC
Commentary on Twitter
CONFIRM Trial: a phase III study demonstrated longer PFS and OS with Nivolumab compared with Placebo in patients with Pleural or Peritoneal Malignant Mesothelioma who have progressed following platinum-based chemotherapy @OncoAlert #LCSM https://t.co/jKoKXEXgpB
— Dipesh Uprety MD FACP (@dipeshuprety4) October 15, 2021