Daily Archives: October 7, 2021
Observational study in Qatar showed the effectiveness of Pfizer vaccine against any SARS-CoV-2 infection dropped to 20% in months 5 through 7 after the second dose, but effectiveness against severe Covid-19 remained high.
7 Oct, 2021 | 10:55h | UTC
Commentary on Twitter
In this 900,000-participant study in Qatar, vaccine effectiveness peaked at 77.5% in the first month after the second dose. The effectiveness fell to as low as 20% in months 5 through 7 after vaccination. #Covid19vaccine #IDTwttier https://t.co/TeDcLLftIH pic.twitter.com/pEBoxs6Hmr
— NEJM (@NEJM) October 6, 2021
Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.
7 Oct, 2021 | 10:51h | UTCCommentary: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD
Related Study: Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine
Commentaries on Twitter
Among 2.5 million patients who received the BNT162b2 mRNA vaccine in a large Israeli health care system, the incidence of myocarditis at 42 days was 2.13 cases per 100,000 persons. #Covid19vaccine #IDTwitter https://t.co/EzmsaW2u4Y pic.twitter.com/P95eUm8xo9
— NEJM (@NEJM) October 6, 2021
Just out in @NEJM: Two studies on myocarditis after vaccination with Pfizer
Among 2.5 million vaccinated:
– 54 cases of myocarditis
– 94% men, median 27 y.o.
– Most cases mild, only one fulminanthttps://t.co/xGf7rtwGfr— David Juurlink (@DavidJuurlink) October 6, 2021
Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.
7 Oct, 2021 | 10:49h | UTCMyocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine
Commentary: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD
Related study: Myocarditis after Covid-19 Vaccination in a Large Health Care Organization – New England Journal of Medicine
Commentaries on Twitter
In an Israeli Ministry of Health database, 136 cases of myocarditis were detected among 5 million vaccinated persons. #Covid19vaccine #IDTwitter https://t.co/c1wLBCq8UN pic.twitter.com/D2DAGrIuXe
— NEJM (@NEJM) October 6, 2021
Two new @NEJM reports on Pfizer vaccine related myocarditis: very rare (~2 per 100,000) and usually mild; in-depth review of 190 cases, most cases were in males 16-29 years, 2nd dosehttps://t.co/nHgxXTgQ6ohttps://t.co/pchL0VDi4b pic.twitter.com/7pUxNy36Zo
— Eric Topol (@EricTopol) October 6, 2021
Systematic Review: Administration of antimalarial drugs to whole populations for reducing malaria.
7 Oct, 2021 | 10:36h | UTCAdministration of antimalarial drugs to whole populations for reducing malaria – Cochrane Library
Original study: Mass drug administration for malaria – Cochrane Library
Commentary on Twitter
Administration of #antimalarial drugs to whole populations for reducing #malaria – https://t.co/4Q4vGKwmgU – Updated #OpenAccess @Cochrane_IDG review includes 13 studies and gives implications for practice & future research. pic.twitter.com/EMB2Tihs81
— Cochrane UK (@CochraneUK) October 3, 2021
Perspective | No one is safe until we are all safe.
7 Oct, 2021 | 10:47h | UTCNo one is safe until we are all safe – Science Translational Medicine
Commentary: Covid ‘still running rampant’ worldwide, warns creator of Oxford vaccine – The Guardian
Related: Opinion: Vaccine Nationalism Harms Everyone and Protects No One
Commentary on Twitter
No one is safe until we all are safe, by Sarah Gilbert @JennerInstitute @NDMOxford @UniofOxford and @DrRHatchett @CEPIVaccines
With a forecast of global vaccine supply for 2021https://t.co/iUgC6euvz6 @ScienceTM a large proportion are Sinopharm and Sinovac from China pic.twitter.com/w4KfUAsU45— Eric Topol (@EricTopol) October 6, 2021
WHO approves first ever malaria vaccine for children at risk.
7 Oct, 2021 | 10:40h | UTCWHO recommends groundbreaking malaria vaccine for children at risk – World Health Organization
Commentaries:
WHO Approves First Ever Malaria Vaccine – Health Policy Watch
In major decision, WHO recommends broad rollout of world’s first malaria vaccine – STAT
Why the WHO approval of the first malaria vaccine is a big deal – Vox
WHO greenlights the world’s first malaria vaccine — but it’s not a perfect shot – NPR
The World Health Organization Just Endorsed The World’s First Malaria Vaccine – TIME
WHO Backs Widespread Use Of First Malaria Vaccine – Forbes
World’s 1st malaria vaccine recommended by WHO – LiveScience
Commentaries on Twitter
I started my career as a #malaria researcher, and I longed for the day that we would have an effective vaccine against this ancient and terrible disease. Today is that day: @WHO is recommending the broad use of the world’s first malaria vaccine. #EndMalaria https://t.co/Oh1O155tYj
— Tedros Adhanom Ghebreyesus (@DrTedros) October 6, 2021
(thread – click for more)
A child dies from #malaria every two minutes.
One death is one too many.? Today, WHO recommends RTS,S, a groundbreaking malaria vaccine, to reduce child illness & deaths in areas with moderate and high malaria transmission https://t.co/xSk58nTIV1#VaccinesWork pic.twitter.com/mSECLtRhQs
— World Health Organization (WHO) (@WHO) October 6, 2021
RCT: Immediate drainage did not improve outcomes compared to postponed intervention in patients with infected necrotizing pancreatitis.
7 Oct, 2021 | 10:35h | UTC
Choosing Wisely: Seven things physicians and residents/patients should question in long term care.
7 Oct, 2021 | 10:31h | UTCSee complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Sweden, Denmark pause Moderna COVID-19 vaccine for younger age groups.
7 Oct, 2021 | 10:45h | UTCSweden, Denmark pause Moderna COVID-19 vaccine for younger age groups – Reuters
The Lancet Commission: transforming access to diagnostics.
7 Oct, 2021 | 10:33h | UTCNews release: The Lancet: Half of the global population lack access to basic diagnostics for many common diseases
Video: Transforming access to diagnostics | The Lancet Commission on diagnostics
Homepage: The Lancet Commission on diagnostics: transforming access to diagnostics
The Lancet Commission on diagnostics: transforming access to diagnostics (free registration required)
Transforming access to diagnostics: how to turn good intentions into action? (free registration required)
Can COVID-19 help accelerate and transform the diagnostics agenda?
Commentary: A Grim Diagnosis – Half The World’s Population Has Limited Access To Diagnostics – Forbes
Related:
WHO Updates Global Guidance on Medicines and Diagnostic Tests
The WHO Essential Diagnostic List: A Tool for the Future
Perspective: Health Care is an Essential Human Right – And So Is a Proper Diagnosis
Report: First-ever WHO List of Essential Diagnostic Tests
Commentary on Twitter
The #DiagnosticsCommission is now LIVE on @TheLancet. Visit our website to read the report and to register for our Launch event tomorrow. @FINDdx https://t.co/V3M6IRI7cG pic.twitter.com/hqoJlIwwh5
— Diagnostics Commission (@DiagnosticsCom) October 6, 2021
Large observational study suggests sleeve gastrectomy may be safer compared to gastric bypass in patients with severe obesity.
7 Oct, 2021 | 10:26h | UTCComparative Safety of Sleeve Gastrectomy and Gastric Bypass Up to 5 Years After Surgery in Patients With Severe Obesity – JAMA Surgery (free for a limited period)
Commentaries:
Compared to What?—Novel Methods to Approach Randomization for Long-term Bariatric Surgery Outcomes – JAMA Surgery (free for a limited period)
Of two common weight loss surgeries, one is safer but less effective – Michigan Medicine
Related:
Cohort study: comparing the 5-year diabetes outcomes of sleeve gastrectomy and gastric bypass
Cohort study: interventions and operations 5 years after bariatric surgery
Randomized trial: gastric bypass superior to sleeve gastrectomy for remission of type 2 diabetes
Research: laparoscopic sleeve gastrectomy vs laparoscopic roux-en-y gastric bypass
Commentary on Twitter
Study suggests that the safety benefits of sleeve gastrectomy persist up to 5 years after surgery; this information may help patients and surgeons make informed treatment decisions https://t.co/JuRQGh3byz
— JAMA Surgery (@JAMASurgery) October 6, 2021
RCT: Transanal drainage tube use does not prevent anastomotic leakage after laparoscopic low anterior resection in patients with rectal cancer.
7 Oct, 2021 | 10:27h | UTCTransanal Drainage Tube Use for Preventing Anastomotic Leakage After Laparoscopic Low Anterior Resection in Patients With Rectal Cancer: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited commentary: Transanal Drainage Tubes—Prevention of Leaks or Unnecessary Sump? – JAMA Surgery (free for a limited period)
The Dutch Multidisciplinary Occupational Health Guideline to Enhance Work Participation Among Low Back Pain and Lumbosacral Radicular Syndrome Patients.
7 Oct, 2021 | 10:18h | UTC
Position Paper: Medical management of chronic pancreatitis in children.
7 Oct, 2021 | 10:25h | UTC
Commentary on Twitter
In this position paper on the management of chronic #pancreatitis by the @NASPGHAN #Pancreas Committee:
?? Dietary and endocrinology considerations
?? PERT
?? Medical management of pain
?? Lifestyle modification
?? Sequelae of chronic pancreatitishttps://t.co/7e7NxNAZ80 pic.twitter.com/TGP6Nwd873— JPGN (@JPGNonline) February 1, 2021
Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice.
7 Oct, 2021 | 10:17h | UTC
Commentary on Twitter
The diagnostic yield of genome sequencing in patients with chronic kidney disease is about 30% in children and 15-20% in adults. Should it be performed in clinical practice? @knoers and coauthors provide an informative review and recommendations. https://t.co/Pzwl0ztTLU pic.twitter.com/tWbko9mOyK
— Muin J. Khoury (@MuinJKhoury) July 23, 2021
Evidence and consensus-based recommendations for non-pharmacological treatment of fatigue, hand function loss, Raynaud’s phenomenon, and digital ulcers in patients with systemic sclerosis.
7 Oct, 2021 | 10:19h | UTC
Long-Term Immunosuppression Management: Opportunities and Uncertainties.
7 Oct, 2021 | 10:15h | UTC
Commentary on Twitter
Long-Term Immunosuppression Management: Opportunities and Uncertainties. A Review evaluates the current state of maintenance immunosuppression in kidney transplant recipients and discusses areas of opportunity and uncertainty in their long-term use. https://t.co/8yWp4PVD7t
— CJASN (@CJASN) August 16, 2021
Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents.
7 Oct, 2021 | 10:14h | UTC
Varied extent of mitral annular disjunction among cases with different phenotypes of mitral valve prolapse.
7 Oct, 2021 | 10:12h | UTC
Commentary on Twitter
Varied Extent of #MAD Among Cases With Different Phenotypes of #Mitral Valve #Prolapse ➡️ 3D #YesCCT ➡️ https://t.co/7q4GqIAZQd @JACCJournals @UCLA @argulian @purviparwani @MinnowWalsh @BakhshiHooman @MrinShettyMD @mividovich #JACCCaseReports @gina_lundberg @chiarabd @EstefaniaOS pic.twitter.com/6gVnaBg3cb
— Julia Grapsa (@JGrapsa) August 18, 2021
Key concepts in clinical epidemiology: Stepped wedge trials.
7 Oct, 2021 | 10:10h | UTCKey concepts in clinical epidemiology: Stepped wedge trials – Journal of Clinical Epidemiology
GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings.
7 Oct, 2021 | 10:11h | UTC