Daily Archives: October 5, 2021
Cohort study: Acute myocarditis following COVID-19 mRNA vaccination in adults aged 18 years or older is rare, and most cases are not severe.
5 Oct, 2021 | 10:07h | UTCEditorial: COVID-19 Messenger RNA Vaccination and Myocarditis—A Rare and Mostly Mild Adverse Effect
Commentary on Twitter
New report on very rare acute myocarditis after mRNA vaccination in age 18+
5.8 cases/million after 2nd dose, 0.8/million 1st dose, all cases fully resolved with conservative managementhttps://t.co/Mfh5ImiSpW @KPSCALnews @KPSCalResearch @JAMAInternalMed— Eric Topol (@EricTopol) October 4, 2021
Cohort study: Pfizer vaccine effectiveness against any infections declined from 88% during the first month after full vaccination to 47% after 5 months. Vaccine effectiveness against hospital admissions remained high; 87% within 1 month, and 88% at 5 months after full vaccination, with no significant waning.
5 Oct, 2021 | 10:09h | UTCCommentary: Expert reaction to study on Pfizer-BioNTech vaccine effectiveness up to 6 months – Science Media Centre
Commentary on Twitter
Study of 3.4 million people @aboutKP @TheLancet
Vaccine efficacy against infections:
– First month post: 88%
– 5 months post: 47%But vaccine efficacy against hospitalization (Figure):
– First month post: 87%
– 5 months post: 88 %https://t.co/1Gse0FKpoI pic.twitter.com/p9wyiaWGeg— Vincent Rajkumar (@VincentRK) October 4, 2021
RCT: Another study shows convalescent plasma does not improve outcomes in critically ill patients with Covid-19.
5 Oct, 2021 | 10:06h | UTCRelated:
M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.
RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.
New Zealand acknowledges it can no longer completely get rid of the coronavirus.
5 Oct, 2021 | 10:02h | UTCNew Zealand acknowledges it can no longer completely get rid of the coronavirus – NPR
See also:
New Zealand admits it can no longer get rid of coronavirus – Associated Press
Battling Delta, New Zealand Abandons Its Zero-Covid Ambitions – The New York Times
Video | A Pill For COVID? A Doctor Explains Molnupiravir.
5 Oct, 2021 | 09:57h | UTCA Pill For COVID? | A Doctor Explains Molnupiravir – ZDoggMD
COVID-19 and metabolic disease: mechanisms and clinical management.
5 Oct, 2021 | 10:03h | UTCRelated: Review | Interplay between endocrinology, metabolism, and COVID-19 infection.
Merck’s Covid-19 pill is great news but may not be a game-changer.
5 Oct, 2021 | 09:59h | UTCMerck’s Covid-19 pill is great news but may not be a game-changer – CNN
AAN Position Statement: Ethical perspectives on costly drugs and health care.
5 Oct, 2021 | 08:57h | UTCEthical Perspectives on Costly Drugs and Health Care: AAN Position Statement – Neurology
News release: AAN Issues Ethics Position Statement on Costly Drugs and Health Care – American Academy of Neurology
AHA Scientific Statement: Diagnosis and management of patients with myocardial injury after noncardiac surgery.
5 Oct, 2021 | 09:01h | UTCNews Release: 1 in 5 adults has high levels of heart enzymes after any surgery, monitoring advised – American Heart Association
Commentary: AHA: More Screening Needed to Catch Myocardial Injury After Noncardiac Surgery – TCTMD
Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking.
5 Oct, 2021 | 08:59h | UTC
M-A: Beta-blockers do not reduce the risk of major adverse cardiovascular events in patients with stable coronary artery disease without prior myocardial infarction or left ventricular dysfunction.
5 Oct, 2021 | 08:53h | UTCMeta-Analysis of the Usefulness of Beta-Blockers to Reduce the Risk of Major Adverse Cardiovascular Events in Patients With Stable Coronary Artery Disease Without Prior Myocardial Infarction or Left Ventricular Dysfunction – The American Journal of Medicine (link to abstract – $ for full-text)
Intra-abdominal hypertension and abdominal compartment syndrome in critically ill patients: A narrative review of past, present, and future steps.
5 Oct, 2021 | 08:52h | UTC
Cohort study: Statin therapy initiation linked to increased risk of diabetes progression.
5 Oct, 2021 | 08:56h | UTCCommentaries:
Statin Therapy Initiation and Diabetes Progression – American College of Cardiology
Statin Initiation Linked to Greater Progression of Diabetes – HealthDay
Diabetes progression with initiation of statins – MedicalRessearch.com
Related:
Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes
Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins
Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes
Commentary on Twitter
Large retrospective matched-cohort study found that #statin use was associated with a higher risk of #diabetes treatment escalation and an increased risk of #hyperglycemic complications https://t.co/lFLz7rVfpd
— JAMA Internal Medicine (@JAMAInternalMed) October 4, 2021
Review: Optimizing care for critically ill older adults.
5 Oct, 2021 | 08:51h | UTCOptimizing care for critically ill older adults – Canadian Medical Association Journal
Addressing Biased Patient Behavior: A Teachable Moment.
5 Oct, 2021 | 08:54h | UTCAddressing Biased Patient Behavior: A Teachable Moment – JAMA Internal Medicine
Podcast: Urinary Stone Disease.
5 Oct, 2021 | 08:50h | UTC#298 Urinary Stone Disease Will Rock Your World – The Curbsiders
Evaluating agreement between bodies of evidence from randomized controlled trials and cohort studies in nutrition research: meta-epidemiological study.
5 Oct, 2021 | 08:48h | UTC
Commentary on Twitter
The difference in results between RCTs and cohort studies in nutrition research was small, finds study.
However, with some substantial statistical heterogeneity in cohort studies, differences or potential bias cannot be excluded, say @LSchwingshackl et alhttps://t.co/dyUqhn87V0
— The BMJ (@bmj_latest) September 17, 2021
RCT: Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players.
5 Oct, 2021 | 08:47h | UTC