Daily Archives: September 6, 2021
More data showing increased risk of hospitalization with SARS-CoV-2 delta variant.
6 Sep, 2021 | 11:12h | UTCHospitalisation associated with SARS-CoV-2 delta variant in Denmark – The Lancet Infectious Diseases
The resurgence of SARS-CoV-2 infection in a highly vaccinated health system workforce; vaccine effectiveness against infection was reduced from above 90% from March through June to 65% in July.
6 Sep, 2021 | 11:09h | UTCRelated:
Another study shows Pfizer mRNA vaccine immunity is reduced over time.
Commentary on Twitter (thread – click for more)
? NEW DATA?
1/ "Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce" published today in @NEJM details ↓ in vaccine effectiveness against INFECTION among @UCSDHealth employees – from 95%+ in the spring to 65% in July
?? https://t.co/wMgjoLgJzS pic.twitter.com/lgOwlEqUQG
— Christopher A. Longhurst (@calonghurst) September 1, 2021
RCT: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels.
6 Sep, 2021 | 11:11h | UTC
Commentary on Twitter
The SAVE-MORE phase 3 study demonstrates the efficacy of anakinra, an IL-1α/β inhibitor, in patients with COVID-19 and high serum levels of soluble plasminogen activator receptor, according to a @NatureMedicine paper. https://t.co/aM5teLMipK pic.twitter.com/bTVNqbBOcv
— Nature Portfolio (@NaturePortfolio) September 3, 2021
Large surveillance study finds severe adverse events after COVID-19 mRNA vaccination are rare.
6 Sep, 2021 | 11:02h | UTCSurveillance for Adverse Events After COVID-19 mRNA Vaccination – JAMA
Editorial: Safety Surveillance of COVID-19 mRNA Vaccines Through the Vaccine Safety Datalink – JAMA
Commentaries:
mRNA COVID vaccines not tied to serious side effects – CIDRAP
Researchers find no serious health effects linked to mRNA COVID-19 vaccines – News Medical
Commentary on Twitter
Concerned about the safety of mRNA vaccines? This study of 6.2 million people who got 11.8 million doses is immensely reassuring. https://t.co/nUIqTacl0g pic.twitter.com/JBvenRVrRc
— David Juurlink (@DavidJuurlink) September 4, 2021
Systematic review: evaluation of dietary patterns and all-cause mortality.
6 Sep, 2021 | 10:43h | UTCEvaluation of Dietary Patterns and All-Cause Mortality: A Systematic Review – JAMA Network Open
Commentary on Twitter (thread – click for more)
Great to see work focused on diet patterns (rather than single nutrient/foods)
Nutrient-dense diet patterns, regardless of pattern label/name (Med Diet, DASH, HEI, "plant-based"), were associated with significantly lower risk of death
Commonalities??https://t.co/yQxo4lNJNQ
— Stephan van Vliet (@vanvlietphd) September 1, 2021
Viewpoint | Strengthening global health security and reforming the international health regulations: making the world safer from future pandemics.
6 Sep, 2021 | 11:00h | UTC
Interactive infographic showing the effects of Delta: How coronavirus spreads through a population and how we can beat it.
6 Sep, 2021 | 10:59h | UTCHow coronavirus spreads through a population and how we can beat it – The Guardian
Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.
6 Sep, 2021 | 10:45h | UTCInvited commentary: Integrated approach to stroke burden: are we doing enough? (free registration required)
Commentaries on Twitter
Released today! The analysis within @IHME_UW (@GBD) on #stroke #prevalence and the RFs of stroke has just been published in @TheLancetNeuro! The annual number of strokes (12,2 mln) and #deaths (6,5 mln) due to stroke increased substantially in lat 30 yrs. https://t.co/DUi7SYGyjt pic.twitter.com/7rVcrxZzNF
— Maciej Banach (@maciejbanach) September 3, 2021
? This new #GBDstudy released on @TheLancet examines the #global, regional, and national burden of #stroke and its risk factors
Findings:
▫️The annual number of strokes ⬆️ from 1990-2019
▫️2nd cause of death globally
▫️High Risk factor = high body-mass https://t.co/jnZauEH79M— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) September 3, 2021
Joint editorial: Call for emergency action to limit global temperature increases, restore biodiversity, and protect health.
6 Sep, 2021 | 10:58h | UTC
Commentary on Twitter
A joint editorial published in biomedical journals across the globe calls for swift and decisive action on climate crisis. #HealthyClimate https://t.co/5BMVoUUpNr pic.twitter.com/P3avUzSrvK
— NEJM (@NEJM) September 6, 2021
Study shows cardiac troponin concentrations at presentation are insufficient to distinguish type 1 myocardial infarction from other causes of myocardial injury.
6 Sep, 2021 | 10:42h | UTC
Commentary on Twitter
Cardiac troponin release kinetics: levels at presentation cannot distinguish type 1 MI from other causes of injury or infarction. Results now online @CircAHA https://t.co/8cjyl6SGai@HighSTEACS @chapdoc1 @djlmed @DorienKimenai @EdinUniCVS pic.twitter.com/v0RoD532Jx
— Ryan Wereski (@RyanWereski) June 25, 2021
M-A: Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia.
6 Sep, 2021 | 10:40h | UTCLong-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre–post studies – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
"Taken together, the results suggest increased use of long-acting injectable antipsychotics in clinical practice should be considered."
New Researchhttps://t.co/l2Ow9BzCUu
— The Lancet Psychiatry (@TheLancetPsych) April 14, 2021
AHA Scientific Statement: Genetic testing for heritable cardiovascular diseases in pediatric patients.
6 Sep, 2021 | 10:33h | UTCNews release: Genetic testing in children for heart disorders should be family-centered, include counseling – American Heart Association
Commentary on Twitter
Just out @Circ_Gen Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement: American Heart Association! Fantastic leadership @APLandstrom Honored to be part of it @GenPrecisionMed @AHA_Research #CardioTwitter https://t.co/zEc9tDYAeC pic.twitter.com/49RAkuYCZG
— Prof Chris Semsarian (@CSHeartResearch) August 20, 2021
Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study.
6 Sep, 2021 | 10:36h | UTCDifferentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentary: Can We Detect Central Vertigo on Exam? – Journal Feed
M-A: Effect of monthly injections of naltrexone on alcohol consumption.
6 Sep, 2021 | 10:39h | UTCEffect of extended-release naltrexone on alcohol consumption: a systematic review and meta-analysis – Addiction (link to abstract – $ for full-text)
Position paper on the diagnosis and management of pediatric acute liver failure.
6 Sep, 2021 | 10:31h | UTC